CARM1 and SRCAP

Number of citations of the paper that reports this interaction (PMID 14500758)
11

Data Source:
HPRD (two hybrid, in vivo)

		CARM1	SRCAP
Gene Name		coactivator-associated arginine methyltransferase 1	Snf2-related CREBBP activator protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm Golgi Apparatus Protein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein Methyltransferase Activity Histone-arginine N-methyltransferase Activity Protein-arginine N-methyltransferase Activity Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity (H3-R17 Specific) Histone Methyltransferase Activity Protein Homodimerization Activity Transcription Regulatory Region DNA Binding Lysine-acetylated Histone Binding	DNA Binding Transcription Coactivator Activity Helicase Activity Histone Acetyltransferase Activity Protein Binding ATP Binding
	Biological Process	Regulation Of Growth Plate Cartilage Chondrocyte Proliferation Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Proliferation Pathogenesis Viral Process Histone Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Protein Binding Regulation Of Intracellular Estrogen Receptor Signaling Pathway Histone H3-R2 Methylation Histone H3-R17 Methylation Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Fat Cell Differentiation Response To CAMP Endochondral Bone Morphogenesis	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Histone Acetylation
Pathways		PPARA activates gene expression Organelle biogenesis and maintenance Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Chromatin organization REV-ERBA represses gene expression RORA activates circadian gene expression Mitochondrial biogenesis RMTs methylate histone arginines Regulation of cholesterol biosynthesis by SREBP (SREBF) Chromatin modifying enzymes Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation YAP1- and WWTR1 (TAZ)-stimulated gene expression Activation of gene expression by SREBF (SREBP) Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Transcriptional activation of mitochondrial biogenesis BMAL1:CLOCK,NPAS2 activates circadian gene expression Orphan transporters
Drugs
Diseases
GWAS
Protein-Protein Interactions		33 interactors: AXIN1 CREBBP CTNNB1 DAXX DNAJA3 ELAVL1 EP300 FLII FOS GRIP1 H3F3A H3F3B HIST1H3A MALT1 MEF2D MYOD1 MYOG NCOA1 NCOA2 NUDT21 PABPC1 PABPN1 PIAS1 PYGO1 QKI RABGAP1 RELA SMARCA4 SPAG8 SRC SRCAP TP53 UBE2I	5 interactors: ATG9A CARM1 CREBBP KAT2B NCOA2
Entrez ID		10498	10847
HPRD ID		09158	18103
Ensembl ID		ENSG00000142453	ENSG00000080603
Uniprot IDs		Q86X55	Q6ZRS2
PDB IDs		2Y1W 2Y1X 4IKP
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Peptidyl-lysine Modification Chromatin Organization Transcription, DNA-templated Histone Acetylation RNA Biosynthetic Process Nitrogen Compound Metabolic Process Internal Peptidyl-lysine Acetylation Intracellular Receptor Signaling Pathway Peptidyl-lysine Acetylation Negative Regulation Of Cellular Metabolic Process Internal Protein Amino Acid Acetylation RNA Metabolic Process Protein Acetylation Intracellular Steroid Hormone Receptor Signaling Pathway Organelle Organization Androgen Receptor Signaling Pathway Cellular Macromolecule Biosynthetic Process DNA Methylation On Cytosine Negative Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Regulation Of Cellular Process Chromosome Organization Transcription From RNA Polymerase II Promoter Muscle Structure Development DNA Methylation	N-terminal Peptidyl-lysine Acetylation Histone Modification Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Chromatin Modification N-terminal Protein Amino Acid Acetylation Chromatin Organization Peptidyl-lysine Modification N-terminal Protein Amino Acid Modification Peptidyl-amino Acid Modification Chromosome Organization Rhythmic Process Organelle Organization Viral Process Regulation Of Glucose Metabolic Process Histone H3-R17 Methylation Notch Signaling Pathway Histone H3-K9 Acetylation Regulation Of Protein ADP-ribosylation Late Nucleophagy Piecemeal Microautophagy Of Nucleus Histone H3-R2 Methylation Regulation Of Carbohydrate Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Lipid Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Growth Plate Cartilage Chondrocyte Proliferation Cell Communication DNA-templated Transcription, Initiation Germ-line Stem Cell Maintenance Positive Regulation Of Gluconeogenesis By Positive Regulation Of Transcription From RNA Polymerase II Promoter Lipid Metabolic Process RNA Metabolic Process Cellular Protein Modification Process Regulation Of Cellular Ketone Metabolic Process By Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Protein Localization To Pre-autophagosomal Structure Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Stimulus Gene Expression Regulation Of Protein Glycosylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Positive Regulation Of Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process
Tagcloud ?		additionally arginine biological blocked candidates cardiovascular cofactor compound cyanine docking effectively guide methyltransferase micromolar occupying optimization pentamethine permeated prmt1 prmt5 prmt8 probes provided roadmap selectivity serve systematically transduction trimethine	arid1a ash1l atlas broadly chd6 colorectal concordant copy ep300 ep400 exome gains hypermutation mismatch mll2 mll3 nonhypermutated prdm2 preexisting profiled proofreading resembled seq signatures silico tgfbeta trrap uncertain validating
Tagcloud (Difference) ?		additionally arginine biological blocked candidates cardiovascular cofactor compound cyanine docking effectively guide methyltransferase micromolar occupying optimization pentamethine permeated prmt1 prmt5 prmt8 probes provided roadmap selectivity serve systematically transduction trimethine	arid1a ash1l atlas broadly chd6 colorectal concordant copy ep300 ep400 exome gains hypermutation mismatch mll2 mll3 nonhypermutated prdm2 preexisting profiled proofreading resembled seq signatures silico tgfbeta trrap uncertain validating
Tagcloud (Intersection) ?