CARM1 and NUDT21

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		CARM1	NUDT21
Gene Name		coactivator-associated arginine methyltransferase 1	nudix (nucleoside diphosphate linked moiety X)-type motif 21
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm Centrosome MRNA Cleavage Factor Complex Paraspeckles
	Molecular Function	Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein Methyltransferase Activity Histone-arginine N-methyltransferase Activity Protein-arginine N-methyltransferase Activity Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity (H3-R17 Specific) Histone Methyltransferase Activity Protein Homodimerization Activity Transcription Regulatory Region DNA Binding Lysine-acetylated Histone Binding	RNA Binding MRNA Binding Protein Binding Hydrolase Activity AU-rich Element Binding Protein Homodimerization Activity Histone Deacetylase Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Growth Plate Cartilage Chondrocyte Proliferation Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Proliferation Pathogenesis Viral Process Histone Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Protein Binding Regulation Of Intracellular Estrogen Receptor Signaling Pathway Histone H3-R2 Methylation Histone H3-R17 Methylation Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Fat Cell Differentiation Response To CAMP Endochondral Bone Morphogenesis	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Processing RNA Splicing Gene Expression MRNA 3'-end Processing Protein Tetramerization
Pathways		PPARA activates gene expression Organelle biogenesis and maintenance Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Chromatin organization REV-ERBA represses gene expression RORA activates circadian gene expression Mitochondrial biogenesis RMTs methylate histone arginines Regulation of cholesterol biosynthesis by SREBP (SREBF) Chromatin modifying enzymes Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation YAP1- and WWTR1 (TAZ)-stimulated gene expression Activation of gene expression by SREBF (SREBP) Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Transcriptional activation of mitochondrial biogenesis BMAL1:CLOCK,NPAS2 activates circadian gene expression Orphan transporters	mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Processing of Capped Intronless Pre-mRNA mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		33 interactors: AXIN1 CREBBP CTNNB1 DAXX DNAJA3 ELAVL1 EP300 FLII FOS GRIP1 H3F3A H3F3B HIST1H3A MALT1 MEF2D MYOD1 MYOG NCOA1 NCOA2 NUDT21 PABPC1 PABPN1 PIAS1 PYGO1 QKI RABGAP1 RELA SMARCA4 SPAG8 SRC SRCAP TP53 UBE2I	51 interactors: A2M ATXN1 CARM1 CLP1 CPSF6 CPSF7 CTNND2 DBN1 DNMT3L DYNC1I1 EED EEF1G EXOSC6 F13A1 FBN3 FLAD1 FUNDC2 GOLGA2 HSF4 IKZF1 ITCH JMJD1C KIAA1377 KIFAP3 MASP1 MYL6 NEDD4 NGEF NIF3L1 POLR2C PSMF1 PTN PYCR1 RBM48 RCC1 RNF19A RPLP1 SEMA5B SF3B1 SHC1 SHFM1 SLC44A1 SNCAIP SNRNP70 SRPK1 TCERG1 TLE1 TRA2A TRIM27 WWOX ZBTB48
Entrez ID		10498	11051
HPRD ID		09158	05400
Ensembl ID		ENSG00000142453	ENSG00000167005
Uniprot IDs		Q86X55	O43809
PDB IDs		2Y1W 2Y1X 4IKP	2CL3 2J8Q 3BAP 3BHO 3MDG 3MDI 3N9U 3P5T 3P6Y 3Q2S 3Q2T
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Peptidyl-lysine Modification Chromatin Organization Transcription, DNA-templated Histone Acetylation RNA Biosynthetic Process Nitrogen Compound Metabolic Process Internal Peptidyl-lysine Acetylation Intracellular Receptor Signaling Pathway Peptidyl-lysine Acetylation Negative Regulation Of Cellular Metabolic Process Internal Protein Amino Acid Acetylation RNA Metabolic Process Protein Acetylation Intracellular Steroid Hormone Receptor Signaling Pathway Organelle Organization Androgen Receptor Signaling Pathway Cellular Macromolecule Biosynthetic Process DNA Methylation On Cytosine Negative Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Regulation Of Cellular Process Chromosome Organization Transcription From RNA Polymerase II Promoter Muscle Structure Development DNA Methylation	Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Processing MRNA Processing RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Process Cellular Metabolic Process Viral Process Protein K63-linked Ubiquitination RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Protein Polyubiquitination Negative Regulation Of Complement Activation MRNA 3'-end Processing Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Gene Expression, Epigenetic Immune System Process Developmental Process RNA 3'-end Processing Cellular Macromolecule Biosynthetic Process Regulation Of Dendrite Development Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression By Genetic Imprinting Blood Coagulation Macromolecule Biosynthetic Process Hemostasis Protein Oligomerization MRNA Polyadenylation Anatomical Structure Development
Tagcloud ?		additionally arginine biological blocked candidates cardiovascular cofactor compound cyanine docking effectively guide methyltransferase micromolar occupying optimization pentamethine permeated prmt1 prmt5 prmt8 probes provided roadmap selectivity serve systematically transduction trimethine
Tagcloud (Difference) ?		additionally arginine biological blocked candidates cardiovascular cofactor compound cyanine docking effectively guide methyltransferase micromolar occupying optimization pentamethine permeated prmt1 prmt5 prmt8 probes provided roadmap selectivity serve systematically transduction trimethine
Tagcloud (Intersection) ?