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CABLES1 and CDK3
Number of citations of the paper that reports this interaction (PMID
11733001
)
2
Data Source:
HPRD
(in vitro, in vivo)
CABLES1
CDK3
Gene Name
Cdk5 and Abl enzyme substrate 1
cyclin-dependent kinase 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Molecular Function
Protein Binding
Cyclin-dependent Protein Serine/threonine Kinase Activity
ATP Binding
Biological Process
Cell Cycle
Nervous System Development
Blood Coagulation
Cell Division
G1/S Transition Of Mitotic Cell Cycle
Protein Phosphorylation
Mitotic Nuclear Division
Cell Proliferation
G0 To G1 Transition
Cell Division
Regulation Of Cell Cycle
Pathways
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Height (
20881960
23563607
18391951
20189936
)
Hypertriglyceridemia (
23505323
)
Platelet counts (
22139419
)
Smoking behavior (
19247474
)
Tuberculosis (
20694014
)
Protein-Protein Interactions
8 interactors:
ABL1
CCNA1
CCNE1
CDK3
CDK5
TDRD7
TP53
TP73
18 interactors:
APP
CABLES1
CABLES2
CCNA2
CCNC
CCNE1
CCNE2
CDC37
CDKN1A
CDKN1B
CDKN3
E2F1
E2F2
E2F3
KIR3DL1
NEDD4L
PPARA
RB1
Entrez ID
91768
1018
HPRD ID
16461
00446
Ensembl ID
ENSG00000134508
ENSG00000250506
Uniprot IDs
A7K6Y5
Q8TDN4
Q00526
PDB IDs
1LFN
Enriched GO Terms of Interacting Partners
?
Regulation Of Cell Cycle
Mitotic Cell Cycle Process
Cell Cycle
Mitotic Cell Cycle
Cell Cycle Process
Regulation Of Protein Phosphorylation
Regulation Of Phosphorylation
Regulation Of Neuron Death
Regulation Of Protein Kinase Activity
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Neuron Death
Regulation Of Kinase Activity
Signal Transduction In Response To DNA Damage
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Regulation Of Mitotic Cell Cycle
Cerebellum Development
Cell Division
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Metencephalon Development
Regulation Of Cellular Protein Metabolic Process
DNA Damage Response, Signal Transduction Resulting In Transcription
Negative Regulation Of Cell Cycle
Regulation Of Cell Cycle Process
Cell Cycle Arrest
Regulation Of Protein Metabolic Process
G1/S Transition Of Mitotic Cell Cycle
Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Hindbrain Development
Regulation Of Body Fluid Levels
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Apoptotic Process
Regulation Of Catalytic Activity
Positive Regulation Of Programmed Cell Death
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Cell Death
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Response To X-ray
Release Of Cytochrome C From Mitochondria
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Protein Phosphorylation
Regulation Of Neuron Apoptotic Process
Cell Proliferation
Positive Regulation Of Intracellular Transport
Negative Regulation Of Growth
Mitotic Cell Cycle Phase Transition
Brain Development
Cell Cycle Phase Transition
Regulation Of Actin Cytoskeleton Reorganization
Regulation Of Cell Cycle
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
G1/S Transition Of Mitotic Cell Cycle
Cell Cycle
Regulation Of Protein Kinase Activity
Mitotic Cell Cycle
Regulation Of Kinase Activity
Regulation Of Protein Phosphorylation
Regulation Of Phosphorylation
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle Phase Transition
Mitotic Cell Cycle Process
Cell Cycle Checkpoint
Cell Division
Regulation Of Phosphorus Metabolic Process
Regulation Of Protein Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Regulation Of Cellular Protein Metabolic Process
Cell Cycle Process
Regulation Of Mitotic Cell Cycle
DNA-templated Transcription, Initiation
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle Process
Signal Transduction By P53 Class Mediator
Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Regulation Of Catalytic Activity
Positive Regulation Of Transcription, DNA-templated
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Lens Fiber Cell Apoptotic Process
Notch Signaling Pathway
Regulation Of Gene Expression
Cell Cycle Arrest
Positive Regulation Of Cellular Metabolic Process
DNA Damage Checkpoint
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Positive Regulation Of Macromolecule Biosynthetic Process
Mitotic Cell Cycle Checkpoint
Positive Regulation Of Metabolic Process
Positive Regulation Of Gene Expression
Signal Transduction
Regulation Of Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Intracellular Receptor Signaling Pathway
Positive Regulation Of Fibroblast Proliferation
Negative Regulation Of Cell Cycle
Signaling
Negative Regulation Of Mitotic Cell Cycle
Tagcloud
?
3h
adenovirus
augmented
beta
brdu
cyclin
d2
d3
dedifferentiation
exit
g0
g1
hypothesized
incorporation
inducing
islets
ki67
pancreatic
prb
quiescence
quiescent
rat
recover
regeneration
replace
staining
thymidine
transduced
tunel
Tagcloud (Difference)
?
3h
adenovirus
augmented
beta
brdu
cyclin
d2
d3
dedifferentiation
exit
g0
g1
hypothesized
incorporation
inducing
islets
ki67
pancreatic
prb
quiescence
quiescent
rat
recover
regeneration
replace
staining
thymidine
transduced
tunel
Tagcloud (Intersection)
?