CABLES1 and CDK3

Number of citations of the paper that reports this interaction (PMID 11733001)
2

Data Source:
HPRD (in vitro, in vivo)

		CABLES1	CDK3
Gene Name		Cdk5 and Abl enzyme substrate 1	cyclin-dependent kinase 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol
	Molecular Function	Protein Binding	Cyclin-dependent Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Cell Cycle Nervous System Development Blood Coagulation Cell Division	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Mitotic Nuclear Division Cell Proliferation G0 To G1 Transition Cell Division Regulation Of Cell Cycle
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Height ( 20881960 23563607 18391951 20189936) Hypertriglyceridemia ( 23505323) Platelet counts ( 22139419) Smoking behavior ( 19247474) Tuberculosis ( 20694014)
Protein-Protein Interactions		8 interactors: ABL1 CCNA1 CCNE1 CDK3 CDK5 TDRD7 TP53 TP73	18 interactors: APP CABLES1 CABLES2 CCNA2 CCNC CCNE1 CCNE2 CDC37 CDKN1A CDKN1B CDKN3 E2F1 E2F2 E2F3 KIR3DL1 NEDD4L PPARA RB1
Entrez ID		91768	1018
HPRD ID		16461	00446
Ensembl ID		ENSG00000134508	ENSG00000250506
Uniprot IDs		A7K6Y5 Q8TDN4	Q00526
PDB IDs			1LFN
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Cycle Mitotic Cell Cycle Process Cell Cycle Mitotic Cell Cycle Cell Cycle Process Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Regulation Of Neuron Death Regulation Of Protein Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Neuron Death Regulation Of Kinase Activity Signal Transduction In Response To DNA Damage Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Mitotic Cell Cycle Cerebellum Development Cell Division DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Metencephalon Development Regulation Of Cellular Protein Metabolic Process DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Process Cell Cycle Arrest Regulation Of Protein Metabolic Process G1/S Transition Of Mitotic Cell Cycle Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Hindbrain Development Regulation Of Body Fluid Levels Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Apoptotic Process Regulation Of Catalytic Activity Positive Regulation Of Programmed Cell Death Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Cell Death Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To X-ray Release Of Cytochrome C From Mitochondria Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Positive Regulation Of Protein Phosphorylation Regulation Of Neuron Apoptotic Process Cell Proliferation Positive Regulation Of Intracellular Transport Negative Regulation Of Growth Mitotic Cell Cycle Phase Transition Brain Development Cell Cycle Phase Transition Regulation Of Actin Cytoskeleton Reorganization	Regulation Of Cell Cycle Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G1/S Transition Of Mitotic Cell Cycle Cell Cycle Regulation Of Protein Kinase Activity Mitotic Cell Cycle Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Process Cell Cycle Checkpoint Cell Division Regulation Of Phosphorus Metabolic Process Regulation Of Protein Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Cellular Protein Metabolic Process Cell Cycle Process Regulation Of Mitotic Cell Cycle DNA-templated Transcription, Initiation Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Signal Transduction By P53 Class Mediator Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Catalytic Activity Positive Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Lens Fiber Cell Apoptotic Process Notch Signaling Pathway Regulation Of Gene Expression Cell Cycle Arrest Positive Regulation Of Cellular Metabolic Process DNA Damage Checkpoint Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Macromolecule Biosynthetic Process Mitotic Cell Cycle Checkpoint Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Signal Transduction Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Fibroblast Proliferation Negative Regulation Of Cell Cycle Signaling Negative Regulation Of Mitotic Cell Cycle
Tagcloud ?			3h adenovirus augmented beta brdu cyclin d2 d3 dedifferentiation exit g0 g1 hypothesized incorporation inducing islets ki67 pancreatic prb quiescence quiescent rat recover regeneration replace staining thymidine transduced tunel
Tagcloud (Difference) ?			3h adenovirus augmented beta brdu cyclin d2 d3 dedifferentiation exit g0 g1 hypothesized incorporation inducing islets ki67 pancreatic prb quiescence quiescent rat recover regeneration replace staining thymidine transduced tunel
Tagcloud (Intersection) ?