PUM2 and NANOS1

Number of citations of the paper that reports this interaction (PMID 12690449)
16

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		PUM2	NANOS1
Gene Name		pumilio RNA-binding family member 2	nanos homolog 1 (Drosophila)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoplasmic Stress Granule Nuclear Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Poly(A) RNA Binding	RNA Binding Protein Binding Zinc Ion Binding Translation Repressor Activity
	Biological Process	Regulation Of Translation Stress Granule Assembly	Epithelial Cell Migration Cell Migration Negative Regulation Of Translation Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AURKA DAZ1 DAZ3 DAZ4 DAZL MED23 MED4 NANOS1	3 interactors: GRIN1 GRIN2D PUM2
Entrez ID		23369	340719
HPRD ID		09527	16302
Ensembl ID		ENSG00000055917	ENSG00000188613
Uniprot IDs		B7ZL34 Q8TB72	Q8WY41
PDB IDs		3Q0Q 3Q0R 3Q0S
Enriched GO Terms of Interacting Partners?		Reproduction Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Translational Initiation Spermatogenesis Male Gamete Generation Gamete Generation Female Meiotic Division Sexual Reproduction Regulation Of Translation Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Regulation Of Translational Initiation Positive Regulation Of Translation Female Meiosis II Negative Regulation Of Spindle Checkpoint Single Organism Reproductive Process Reproductive Process Positive Regulation Of Cellular Metabolic Process Spindle Assembly Involved In Female Meiosis I Positive Regulation Of Cell Division Spindle Assembly Involved In Meiosis Spindle Stabilization Meiotic Nuclear Division Transcription Initiation From RNA Polymerase II Promoter Regulation Of Gene Expression Meiotic Cell Cycle Cell Differentiation Positive Regulation Of Metabolic Process Positive Regulation Of Cell Cycle Process DNA-templated Transcription, Initiation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Oocyte Maturation Meiotic Spindle Organization Regulation Of Cell Division Mitotic Centrosome Separation Protein Localization To Centrosome Female Meiosis I Regulation Of Protein Metabolic Process Positive Regulation Of Oocyte Development Centrosome Separation Positive Regulation Of Cell Cycle Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Protein Localization To Cytoskeleton Histone-serine Phosphorylation Positive Regulation Of Meiotic Nuclear Division Positive Regulation Of Protein Metabolic Process Regulation Of Spindle Checkpoint Positive Regulation Of MRNA Catabolic Process Positive Regulation Of Organelle Organization	Startle Response Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Glutamate Receptor Signaling Pathway Neuron-neuron Synaptic Transmission Adult Locomotory Behavior Neuromuscular Process Propylene Metabolic Process Adult Behavior Olfactory Learning Locomotory Behavior Pons Maturation Cellular Response To Manganese Ion Conditioned Taste Aversion Male Mating Behavior Response To Fungicide Olfactory Behavior Single-organism Behavior Pons Development Stress Granule Assembly Synaptic Transmission Behavior Chemosensory Behavior Prepulse Inhibition Response To Manganese Ion Suckling Behavior Regulation Of Respiratory Gaseous Exchange Regulation Of Sensory Perception Of Pain Regulation Of Long-term Neuronal Synaptic Plasticity Mating Behavior Positive Regulation Of Excitatory Postsynaptic Membrane Potential Response To Amphetamine Cell-cell Signaling Response To Morphine Social Behavior Positive Regulation Of Membrane Potential Long-term Memory Response To Amine Mating Neurological System Process Respiratory Gaseous Exchange Regulation Of Neurological System Process Regulation Of Neuronal Synaptic Plasticity Regulation Of Synapse Assembly Visual Learning Visual Behavior Ion Transmembrane Transport Regulation Of Dendrite Morphogenesis Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential
Tagcloud ?			antagonistic capabilities cdk6 demethylase demethylases depleted dimethylated dysregulated ectopic fbxl11 h3k36 hdac3 invasion invasiveness jhdm1a kdm2a methyltransferases nsclc occupied overexpressing recovered releases removing represses rescued substantially transcriptionally tumorigenic tumorigenicity
Tagcloud (Difference) ?			antagonistic capabilities cdk6 demethylase demethylases depleted dimethylated dysregulated ectopic fbxl11 h3k36 hdac3 invasion invasiveness jhdm1a kdm2a methyltransferases nsclc occupied overexpressing recovered releases removing represses rescued substantially transcriptionally tumorigenic tumorigenicity
Tagcloud (Intersection) ?