PUM2 and DAZ4

Number of citations of the paper that reports this interaction (PMID 12511597)
43

Data Source:
HPRD (in vivo, two hybrid)

		PUM2	DAZ4
Gene Name		pumilio RNA-binding family member 2	deleted in azoospermia 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoplasmic Stress Granule Nuclear Membrane Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Protein Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding
	Biological Process	Regulation Of Translation Stress Granule Assembly	Multicellular Organismal Development Spermatogenesis Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AURKA DAZ1 DAZ3 DAZ4 DAZL MED23 MED4 NANOS1	5 interactors: BOLL DAZL DZIP1 PUM2 QKI
Entrez ID		23369	57135
HPRD ID		09527	13117
Ensembl ID		ENSG00000055917	ENSG00000205916
Uniprot IDs		B7ZL34 Q8TB72	Q658T2 Q86SG3
PDB IDs		3Q0Q 3Q0R 3Q0S
Enriched GO Terms of Interacting Partners?		Reproduction Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Translational Initiation Spermatogenesis Male Gamete Generation Gamete Generation Female Meiotic Division Sexual Reproduction Regulation Of Translation Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Regulation Of Translational Initiation Positive Regulation Of Translation Female Meiosis II Negative Regulation Of Spindle Checkpoint Single Organism Reproductive Process Reproductive Process Positive Regulation Of Cellular Metabolic Process Spindle Assembly Involved In Female Meiosis I Positive Regulation Of Cell Division Spindle Assembly Involved In Meiosis Spindle Stabilization Meiotic Nuclear Division Transcription Initiation From RNA Polymerase II Promoter Regulation Of Gene Expression Meiotic Cell Cycle Cell Differentiation Positive Regulation Of Metabolic Process Positive Regulation Of Cell Cycle Process DNA-templated Transcription, Initiation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Oocyte Maturation Meiotic Spindle Organization Regulation Of Cell Division Mitotic Centrosome Separation Protein Localization To Centrosome Female Meiosis I Regulation Of Protein Metabolic Process Positive Regulation Of Oocyte Development Centrosome Separation Positive Regulation Of Cell Cycle Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Protein Localization To Cytoskeleton Histone-serine Phosphorylation Positive Regulation Of Meiotic Nuclear Division Positive Regulation Of Protein Metabolic Process Regulation Of Spindle Checkpoint Positive Regulation Of MRNA Catabolic Process Positive Regulation Of Organelle Organization	Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Spermatogenesis Male Gamete Generation Gamete Generation Positive Regulation Of Translational Initiation Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Germ Cell Development Reproduction Single Organism Reproductive Process Reproductive Process Regulation Of Translational Initiation Positive Regulation Of Translation Female Meiosis II Regulation Of Cellular Protein Metabolic Process Developmental Process Involved In Reproduction Regulation Of Protein Metabolic Process 3'-UTR-mediated MRNA Destabilization Meiotic Nuclear Division Meiotic Cell Cycle MRNA Destabilization Organelle Organization Cell Differentiation RNA Destabilization Positive Regulation Of Gene Expression Stress Granule Assembly Long-chain Fatty Acid Biosynthetic Process Organelle Assembly Positive Regulation Of Meiotic Nuclear Division Cell Development Oocyte Maturation Multicellular Organismal Development Regulation Of Gene Expression Female Meiotic Division Regulation Of Meiosis Oocyte Development Oocyte Differentiation Regulation Of MRNA Stability Regulation Of Meiotic Cell Cycle Regulation Of RNA Stability Developmental Process Oogenesis Positive Regulation Of Cellular Protein Metabolic Process Vasculogenesis
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