PUM2 and DAZ1

Number of citations of the paper that reports this interaction (PMID 12511597)
43

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (in vitro, in vivo, two hybrid)

		PUM2	DAZ1
Gene Name		pumilio RNA-binding family member 2	deleted in azoospermia 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoplasmic Stress Granule Nuclear Membrane Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Protein Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding Protein Binding Translation Activator Activity
	Biological Process	Regulation Of Translation Stress Granule Assembly	Multicellular Organismal Development Spermatogenesis Cell Differentiation Positive Regulation Of Translational Initiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AURKA DAZ1 DAZ3 DAZ4 DAZL MED23 MED4 NANOS1	10 interactors: BOLL DAZAP1 DAZAP2 DAZL DYNLL1 DZIP1 DZIP1L DZIP3 PUM2 QKI
Entrez ID		23369	1617
HPRD ID		09527	15958
Ensembl ID		ENSG00000055917	ENSG00000188120
Uniprot IDs		B7ZL34 Q8TB72	Q1RMF9 Q86SG3 Q9NQZ3
PDB IDs		3Q0Q 3Q0R 3Q0S
Enriched GO Terms of Interacting Partners?		Reproduction Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Translational Initiation Spermatogenesis Male Gamete Generation Gamete Generation Female Meiotic Division Sexual Reproduction Regulation Of Translation Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Regulation Of Translational Initiation Positive Regulation Of Translation Female Meiosis II Negative Regulation Of Spindle Checkpoint Single Organism Reproductive Process Reproductive Process Positive Regulation Of Cellular Metabolic Process Spindle Assembly Involved In Female Meiosis I Positive Regulation Of Cell Division Spindle Assembly Involved In Meiosis Spindle Stabilization Meiotic Nuclear Division Transcription Initiation From RNA Polymerase II Promoter Regulation Of Gene Expression Meiotic Cell Cycle Cell Differentiation Positive Regulation Of Metabolic Process Positive Regulation Of Cell Cycle Process DNA-templated Transcription, Initiation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Oocyte Maturation Meiotic Spindle Organization Regulation Of Cell Division Mitotic Centrosome Separation Protein Localization To Centrosome Female Meiosis I Regulation Of Protein Metabolic Process Positive Regulation Of Oocyte Development Centrosome Separation Positive Regulation Of Cell Cycle Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Protein Localization To Cytoskeleton Histone-serine Phosphorylation Positive Regulation Of Meiotic Nuclear Division Positive Regulation Of Protein Metabolic Process Regulation Of Spindle Checkpoint Positive Regulation Of MRNA Catabolic Process Positive Regulation Of Organelle Organization	Gamete Generation Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Spermatogenesis Male Gamete Generation Reproduction Single Organism Reproductive Process Regulation Of Translation Reproductive Process Positive Regulation Of Translational Initiation Posttranscriptional Regulation Of Gene Expression Developmental Process Involved In Reproduction Germ Cell Development Organelle Organization Regulation Of Translational Initiation Positive Regulation Of Translation Female Meiosis II Organelle Assembly 3'-UTR-mediated MRNA Destabilization Female Gamete Generation Developmental Process Positive Regulation Of Gene Expression Meiotic Nuclear Division Cilium Assembly Cilium Organization MRNA Destabilization Meiotic Cell Cycle Cilium Morphogenesis Multicellular Organismal Development Regulation Of Gene Expression Anatomical Structure Development RNA Destabilization Regulation Of Cellular Protein Metabolic Process Cell Differentiation Cell Projection Assembly Stress Granule Assembly Long-chain Fatty Acid Biosynthetic Process Regulation Of Protein Metabolic Process Positive Regulation Of Meiotic Nuclear Division Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Anatomical Structure Morphogenesis Oocyte Maturation Positive Regulation Of Organelle Organization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome Cell Cycle Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of RNA Splicing Female Meiotic Division
Tagcloud ?			cfsdna clpb coincident detecting dnmt3l epididymis fragments gml hoxa5 medip methylated methylation morc1 msh4 normozoospermia nz obviously peg10 prame promoters pv qpcr quantitatively semen seminal snurf testis ultrasonication vasectomy
Tagcloud (Difference) ?			cfsdna clpb coincident detecting dnmt3l epididymis fragments gml hoxa5 medip methylated methylation morc1 msh4 normozoospermia nz obviously peg10 prame promoters pv qpcr quantitatively semen seminal snurf testis ultrasonication vasectomy
Tagcloud (Intersection) ?