PUM2 and DAZL

Number of citations of the paper that reports this interaction (PMID 12511597)
43

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		PUM2	DAZL
Gene Name		pumilio RNA-binding family member 2	deleted in azoospermia-like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoplasmic Stress Granule Nuclear Membrane Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Polysome
	Molecular Function	Protein Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Translation Activator Activity Identical Protein Binding
	Biological Process	Regulation Of Translation Stress Granule Assembly	Oocyte Maturation Female Meiosis II Multicellular Organismal Development Germ Cell Development Spermatogenesis Positive Regulation Of Meiotic Nuclear Division Positive Regulation Of Translational Initiation
Pathways
Drugs
Diseases
GWAS			Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		8 interactors: AURKA DAZ1 DAZ3 DAZ4 DAZL MED23 MED4 NANOS1	5 interactors: DAZ1 DAZ4 DAZAP1 DAZAP2 PUM2
Entrez ID		23369	1618
HPRD ID		09527	09029
Ensembl ID		ENSG00000055917	ENSG00000092345
Uniprot IDs		B7ZL34 Q8TB72	Q92904
PDB IDs		3Q0Q 3Q0R 3Q0S
Enriched GO Terms of Interacting Partners?		Reproduction Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Translational Initiation Spermatogenesis Male Gamete Generation Gamete Generation Female Meiotic Division Sexual Reproduction Regulation Of Translation Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Regulation Of Translational Initiation Positive Regulation Of Translation Female Meiosis II Negative Regulation Of Spindle Checkpoint Single Organism Reproductive Process Reproductive Process Positive Regulation Of Cellular Metabolic Process Spindle Assembly Involved In Female Meiosis I Positive Regulation Of Cell Division Spindle Assembly Involved In Meiosis Spindle Stabilization Meiotic Nuclear Division Transcription Initiation From RNA Polymerase II Promoter Regulation Of Gene Expression Meiotic Cell Cycle Cell Differentiation Positive Regulation Of Metabolic Process Positive Regulation Of Cell Cycle Process DNA-templated Transcription, Initiation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Oocyte Maturation Meiotic Spindle Organization Regulation Of Cell Division Mitotic Centrosome Separation Protein Localization To Centrosome Female Meiosis I Regulation Of Protein Metabolic Process Positive Regulation Of Oocyte Development Centrosome Separation Positive Regulation Of Cell Cycle Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Protein Localization To Cytoskeleton Histone-serine Phosphorylation Positive Regulation Of Meiotic Nuclear Division Positive Regulation Of Protein Metabolic Process Regulation Of Spindle Checkpoint Positive Regulation Of MRNA Catabolic Process Positive Regulation Of Organelle Organization	Spermatogenesis Male Gamete Generation Gamete Generation Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Reproduction Single Organism Reproductive Process Reproductive Process Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Translational Initiation Stress Granule Assembly Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Maternal Placenta Development Cell Differentiation Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Translational Initiation Positive Regulation Of Translation Maternal Process Involved In Female Pregnancy Regulation Of MRNA Processing Regulation Of RNA Splicing
Tagcloud ?			122c 2012cb944901 9qh azoospermia blimp1 ddx4 declare dppa3 envisioned fam122c funds grants hef ikbkg ipsc ipscs lin28 poi poi1 poi2 prdm1 q26 rbmx stella sublines talents vasa xq znf
Tagcloud (Difference) ?			122c 2012cb944901 9qh azoospermia blimp1 ddx4 declare dppa3 envisioned fam122c funds grants hef ikbkg ipsc ipscs lin28 poi poi1 poi2 prdm1 q26 rbmx stella sublines talents vasa xq znf
Tagcloud (Intersection) ?