PUM2 and MED23

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		PUM2	MED23
Gene Name		pumilio RNA-binding family member 2	mediator complex subunit 23
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoplasmic Stress Granule Nuclear Membrane Perinuclear Region Of Cytoplasm	Nucleoplasm Transcription Factor Complex Mediator Complex
	Molecular Function	Protein Binding Poly(A) RNA Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Regulation Of Translation Stress Granule Assembly	Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AURKA DAZ1 DAZ3 DAZ4 DAZL MED23 MED4 NANOS1	14 interactors: CEBPB CTDP1 ELF3 ESR1 ESR2 ETS1 FOXJ3 MED13 MED9 NCOA6 PUM2 RELA SREBF1 WDTC1
Entrez ID		23369	9439
HPRD ID		09527	05436
Ensembl ID		ENSG00000055917	ENSG00000112282
Uniprot IDs		B7ZL34 Q8TB72	Q05DL5 Q9ULK4
PDB IDs		3Q0Q 3Q0R 3Q0S
Enriched GO Terms of Interacting Partners?		Reproduction Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Translational Initiation Spermatogenesis Male Gamete Generation Gamete Generation Female Meiotic Division Sexual Reproduction Regulation Of Translation Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Regulation Of Translational Initiation Positive Regulation Of Translation Female Meiosis II Negative Regulation Of Spindle Checkpoint Single Organism Reproductive Process Reproductive Process Positive Regulation Of Cellular Metabolic Process Spindle Assembly Involved In Female Meiosis I Positive Regulation Of Cell Division Spindle Assembly Involved In Meiosis Spindle Stabilization Meiotic Nuclear Division Transcription Initiation From RNA Polymerase II Promoter Regulation Of Gene Expression Meiotic Cell Cycle Cell Differentiation Positive Regulation Of Metabolic Process Positive Regulation Of Cell Cycle Process DNA-templated Transcription, Initiation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Oocyte Maturation Meiotic Spindle Organization Regulation Of Cell Division Mitotic Centrosome Separation Protein Localization To Centrosome Female Meiosis I Regulation Of Protein Metabolic Process Positive Regulation Of Oocyte Development Centrosome Separation Positive Regulation Of Cell Cycle Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Protein Localization To Cytoskeleton Histone-serine Phosphorylation Positive Regulation Of Meiotic Nuclear Division Positive Regulation Of Protein Metabolic Process Regulation Of Spindle Checkpoint Positive Regulation Of MRNA Catabolic Process Positive Regulation Of Organelle Organization	Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Intracellular Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Gland Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Response To Hormone Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Response To Lipid Response To Steroid Hormone DNA-templated Transcription, Initiation Cellular Response To Hormone Stimulus Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Response To Organic Substance Vagina Development Uterus Development Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Female Genitalia Development Mammary Gland Epithelial Cell Proliferation Cellular Response To Lipid
Tagcloud ?			acetyltransferases ad5 adenovirus capable cbp compete cr3 cr3s dramatic e1a expanded experimentally hsug1 largest mediator modeled modest pcaf prototype representative s8 squelching sug1 suggestive tata tbp transactivation unidentified v147l
Tagcloud (Difference) ?			acetyltransferases ad5 adenovirus capable cbp compete cr3 cr3s dramatic e1a expanded experimentally hsug1 largest mediator modeled modest pcaf prototype representative s8 squelching sug1 suggestive tata tbp transactivation unidentified v147l
Tagcloud (Intersection) ?