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JADE2 and ING4
Number of citations of the paper that reports this interaction (PMID
20211142
)
148
Data Source:
BioGRID
(affinity chromatography technology, two hybrid)
JADE2
ING4
Gene Name
jade family PHD finger 2
inhibitor of growth family, member 4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Histone Acetyltransferase Complex
Nucleoplasm
Extracellular Vesicular Exosome
Histone Acetyltransferase Complex
Nucleus
Nucleoplasm
Molecular Function
Zinc Ion Binding
Transcription Coactivator Activity
Protein Binding
Zinc Ion Binding
Methylated Histone Binding
Biological Process
Histone H3 Acetylation
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Histone H4-K12 Acetylation
Histone H4-K16 Acetylation
SMAD Protein Signal Transduction
DNA Replication
Chromatin Organization
Protein Acetylation
Apoptotic Process
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Cell Cycle Arrest
Negative Regulation Of Cell Proliferation
Positive Regulation Of Apoptotic Process
Histone H3 Acetylation
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Histone H4-K12 Acetylation
Histone H4-K16 Acetylation
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Growth
Pathways
Chromatin modifying enzymes
Chromatin organization
HATs acetylate histones
Chromatin modifying enzymes
Chromatin organization
HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions
8 interactors:
GORASP2
HIST3H3
ING4
ING5
PACSIN1
ZBTB3
ZBTB5
ZNF496
17 interactors:
CDC34
EGLN1
EP300
HIST1H3A
HIST3H3
HNRNPD
HOXB9
JADE1
JADE2
KAT7
MSX1
MYC
NAV2
RELA
SUV39H1
TLX3
TP53
Entrez ID
23338
51147
HPRD ID
15124
09774
Ensembl ID
ENSG00000043143
ENSG00000111653
Uniprot IDs
B3KPL2
D3DQA3
G3XAA4
Q9NQC1
Q9UNL4
PDB IDs
2K1J
2M1R
2PNX
2VNF
4AFL
Enriched GO Terms of Interacting Partners
?
Histone H3 Acetylation
Histone Acetylation
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Protein Acetylation
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Organelle Organization
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Negative Regulation Of Growth
Cellular Macromolecule Biosynthetic Process
Peptidyl-lysine Modification
Macromolecule Biosynthetic Process
Histone H4-K12 Acetylation
DNA Replication
Chromosome Organization
DNA Metabolic Process
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Transcription, DNA-templated
DNA Damage Response, Signal Transduction Resulting In Transcription
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
RNA Biosynthetic Process
Membrane Tubulation
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Histone Modification
Regulation Of RNA Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Synaptic Vesicle Endocytosis
Regulation Of Nitrogen Compound Metabolic Process
Synaptic Vesicle Recycling
Chromosome Organization
Chromatin Organization
Histone H4-K12 Acetylation
Histone H4 Acetylation
Heterocycle Metabolic Process
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Hypoxia
Transcription, DNA-templated
Cellular Response To Decreased Oxygen Levels
Peptidyl-lysine Modification
Cellular Aromatic Compound Metabolic Process
RNA Biosynthetic Process
Cellular Response To Oxygen Levels
Histone Acetylation
Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Cellular Nitrogen Compound Metabolic Process
Protein Acetylation
Chromatin Modification
Gene Expression
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Gene Expression
Histone H3 Acetylation
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Biosynthetic Process
Macromolecule Biosynthetic Process
Histone Modification
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
RNA Metabolic Process
Cellular Response To Nicotine
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Anterior/posterior Pattern Specification
Tagcloud
?
aad
adenovirus
adopted
apparently
arrested
bax
bcl
blot
caspase
cleaved
cne
differential
efect
g2
measure
mtt
nasopharyngeal
obviously
overexpressed
p21
pe
probable
regulating
rgd
rt
survivin
synergies
vector
western
Tagcloud (Difference)
?
aad
adenovirus
adopted
apparently
arrested
bax
bcl
blot
caspase
cleaved
cne
differential
efect
g2
measure
mtt
nasopharyngeal
obviously
overexpressed
p21
pe
probable
regulating
rgd
rt
survivin
synergies
vector
western
Tagcloud (Intersection)
?