JADE2 and PACSIN1

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		JADE2	PACSIN1
Gene Name		jade family PHD finger 2	protein kinase C and casein kinase substrate in neurons 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Extracellular Vesicular Exosome	Cytoplasm Endosome Cytosol Plasma Membrane Membrane Cell Junction COPI-coated Vesicle Cytoplasmic Vesicle Membrane Membrane-bounded Vesicle Ruffle Membrane Neuron Projection Axon Terminus Synapse Perinuclear Region Of Cytoplasm
	Molecular Function	Zinc Ion Binding	Protein Binding Phospholipid Binding Cytoskeletal Protein Binding
	Biological Process	Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation SMAD Protein Signal Transduction	Cytoskeleton Organization Actin Filament Organization Regulation Of Endocytosis Negative Regulation Of Endocytosis Synaptic Vesicle Endocytosis Neuron Projection Morphogenesis Protein Localization To Membrane Establishment Of Protein Localization To Plasma Membrane Membrane Tubulation Positive Regulation Of Dendrite Development
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: GORASP2 HIST3H3 ING4 ING5 PACSIN1 ZBTB3 ZBTB5 ZNF496	24 interactors: ANKRD24 ARHGAP17 ATP8 COBL COBLL1 DNM1 EHBP1 FTH1 GAS7 HTT JADE2 KAT7 KHDRBS1 PACSIN2 PACSIN3 POT1 RTKN2 SOS1 SPTBN1 SYNJ1 TPM4 TRPV4 WASF2 WASL
Entrez ID		23338	29993
HPRD ID		15124	05936
Ensembl ID		ENSG00000043143	ENSG00000124507
Uniprot IDs		B3KPL2 D3DQA3 G3XAA4 Q9NQC1	Q5TZC3 Q9BY11
PDB IDs			3HAH 3HAI 3Q84 3QNI
Enriched GO Terms of Interacting Partners?		Histone H3 Acetylation Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Organelle Organization Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Growth Cellular Macromolecule Biosynthetic Process Peptidyl-lysine Modification Macromolecule Biosynthetic Process Histone H4-K12 Acetylation DNA Replication Chromosome Organization DNA Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Transcription, DNA-templated DNA Damage Response, Signal Transduction Resulting In Transcription Histone H4-K5 Acetylation Histone H4-K8 Acetylation RNA Biosynthetic Process Membrane Tubulation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Histone Modification Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Gene Expression Synaptic Vesicle Endocytosis Regulation Of Nitrogen Compound Metabolic Process Synaptic Vesicle Recycling	Cell Projection Morphogenesis Cell Part Morphogenesis Actin Filament-based Process Endocytosis Cellular Component Assembly Vesicle-mediated Transport Cell Morphogenesis Regulation Of Cellular Component Organization Organelle Organization Cytoskeleton Organization Cell Projection Organization Actin Cytoskeleton Organization Neuron Development Neuron Projection Morphogenesis Regulation Of Endocytosis Actin Filament-based Movement Endomembrane System Organization Generation Of Neurons Neuron Differentiation Histone H4-K12 Acetylation Membrane Tubulation Neurogenesis Neuron Projection Development Actin Polymerization Or Depolymerization Histone H4-K5 Acetylation Histone H4-K8 Acetylation Membrane Organization Axonogenesis Cell Development Enzyme Linked Receptor Protein Signaling Pathway Protein Polymerization Anatomical Structure Morphogenesis Axon Development Regulation Of Cellular Process Regulation Of Protein Depolymerization Positive Regulation Of Protein Depolymerization Actin Filament Organization Cell Morphogenesis Involved In Neuron Differentiation Membrane Assembly Regulation Of Cell Projection Assembly Regulation Of Protein Complex Disassembly Protein Complex Assembly Movement Of Cell Or Subcellular Component Cellular Protein Complex Assembly Membrane Biogenesis Cell Differentiation Regulation Of Vesicle-mediated Transport Positive Regulation Of Protein Complex Disassembly Cell Morphogenesis Involved In Differentiation Axon Guidance
Tagcloud ?			10a autophagic autophagosome autophagosomes bub1 catabolic cdkl3 csnk1a1 dapk2 endolysosomal flux functioned immortalized kinome macroautophagy maintains manipulation mcf mtorc1 nek4 pklr possibilities protects scyl1 shed sirnas starvation stresses wnk2
Tagcloud (Difference) ?			10a autophagic autophagosome autophagosomes bub1 catabolic cdkl3 csnk1a1 dapk2 endolysosomal flux functioned immortalized kinome macroautophagy maintains manipulation mcf mtorc1 nek4 pklr possibilities protects scyl1 shed sirnas starvation stresses wnk2
Tagcloud (Intersection) ?