JADE2 and GORASP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		JADE2	GORASP2
Gene Name		jade family PHD finger 2	golgi reassembly stacking protein 2, 55kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Extracellular Vesicular Exosome	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Zinc Ion Binding	Protein Binding
	Biological Process	Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation SMAD Protein Signal Transduction	Mitotic Cell Cycle Organelle Organization
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones	Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Cognitive performance ( 19734545)
Protein-Protein Interactions		8 interactors: GORASP2 HIST3H3 ING4 ING5 PACSIN1 ZBTB3 ZBTB5 ZNF496	69 interactors: AAMDC ACY3 AES APP ARL6IP1 ATXN1L BEND5 BLZF1 C1orf94 CBLB CCDC153 CDC23 CRYAA DCTD DMC1 DPYSL2 DUSP21 EIF2B1 ENOX1 GABPB2 GOLGA2 JADE2 KCTD5 KCTD9 KIFC3 LONRF1 LTBP3 MAP1LC3B MAPK1 MAPK14 MAPK8 MID2 MIF MORN2 NME1 NQO2 NUP62 ODC1 PCBD1 PDE9A PNMA5 PRDX3 PRPS1 PRRC2A PSMA3 RAB1A RAB2A RAD54B RGS3 RPIA SCAND1 SELENBP1 STOX1 TCF4 TEKT3 TGFA TMED10 TMED2 TMED3 TRAF1 TRAF2 TRAF4 TRAF5 TRIM38 TSC22D4 TXLNA ZBTB14 ZMAT1 ZNF148
Entrez ID		23338	26003
HPRD ID		15124	08303
Ensembl ID		ENSG00000043143	ENSG00000115806
Uniprot IDs		B3KPL2 D3DQA3 G3XAA4 Q9NQC1	B4DKT0 B4DNR1 Q9H8Y8
PDB IDs			3RLE 4EDJ
Enriched GO Terms of Interacting Partners?		Histone H3 Acetylation Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Organelle Organization Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Growth Cellular Macromolecule Biosynthetic Process Peptidyl-lysine Modification Macromolecule Biosynthetic Process Histone H4-K12 Acetylation DNA Replication Chromosome Organization DNA Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Transcription, DNA-templated DNA Damage Response, Signal Transduction Resulting In Transcription Histone H4-K5 Acetylation Histone H4-K8 Acetylation RNA Biosynthetic Process Membrane Tubulation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Histone Modification Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Gene Expression Synaptic Vesicle Endocytosis Regulation Of Nitrogen Compound Metabolic Process Synaptic Vesicle Recycling	Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Protein Binding Regulation Of Binding Positive Regulation Of NF-kappaB Transcription Factor Activity Golgi Organization Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Regulation Of MAP Kinase Activity Regulation Of Cell Death Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cargo Loading Into Vesicle Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Protein Transport Positive Regulation Of Signal Transduction Regulation Of Protein Kinase Activity Establishment Of Protein Localization Intracellular Protein Transport Regulation Of Protein Homodimerization Activity Regulation Of MAPK Cascade TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Metabolic Process MyD88-independent Toll-like Receptor Signaling Pathway COPII-coated Vesicle Budding Regulation Of Nitrogen Compound Metabolic Process Toll-like Receptor 3 Signaling Pathway Establishment Of Localization In Cell Regulation Of Signal Transduction Positive Regulation Of Cell Proliferation Negative Regulation Of Cellular Metabolic Process Protein Complex Assembly Positive Regulation Of Protein Metabolic Process Protein Homooligomerization Toll-like Receptor 4 Signaling Pathway Cell Death Death Positive Regulation Of Protein Serine/threonine Kinase Activity Protein Localization Positive Regulation Of Transferase Activity Cellular Localization Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Apoptotic Process Protein Ubiquitination Intracellular Transport Negative Regulation Of Programmed Cell Death Negative Regulation Of Transferase Activity Protein Oligomerization Endomembrane System Organization Cell Cycle Cellular Protein Localization
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