JADE2 and DDX46

		JADE2	DDX46
Description		jade family PHD finger 2	DEAD-box helicase 46
Image		No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Extracellular Exosome	Fibrillar Center Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP Cajal Body Nuclear Speck
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Histone H3K14 Acetyltransferase Activity Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Metal Ion Binding Histone H4K16 Acetyltransferase Activity Ubiquitin Protein Ligase Activity	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity
	Biological Process	Regulation Of Cell Growth Regulation Of DNA Replication Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination Regulation Of Cell Cycle Regulation Of DNA Biosynthetic Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing U2-type Prespliceosome Assembly
Pathways		HATs acetylate histones	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 34211149 27798627) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Coffee consumption ( 31046077) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Mental health study participation (completed survey) ( 31263887) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Platelet distribution width ( 27863252) Smoking cessation ( 33082346) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 28869590) White blood cell count ( 32888494)	Height ( 18391951)
Interacting Genes		15 interacting genes: CBX8 CDCA7L CSNK2A1 FBXO7 GAS2L2 GORASP2 H3-4 ING4 PACSIN1 SASH1 TTC3 ZBTB3 ZBTB5 ZNF417 ZNF496	4 interacting genes: APBB1 LINC01554 RNF10 SRPK2
Entrez ID		23338	9879
HPRD ID		15124	10862
Ensembl ID		ENSG00000043143	ENSG00000145833
Uniprot IDs		A0A087X085 A0A0C4DFT8 B3KPL2 B4DFY8 G3XAA4 Q9NQC1	A0A0C4DG89 Q7L014
PDB IDs			6Y50 6Y53 6Y5Q 7EVO 7Q3L 7VPX
Enriched GO Terms of Interacting Partners?
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