PACSIN1 and EHBP1

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		PACSIN1	EHBP1
Gene Name		protein kinase C and casein kinase substrate in neurons 1	EH domain binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Endosome Cytosol Plasma Membrane Membrane Cell Junction COPI-coated Vesicle Cytoplasmic Vesicle Membrane Membrane-bounded Vesicle Ruffle Membrane Neuron Projection Axon Terminus Synapse Perinuclear Region Of Cytoplasm	Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding Phospholipid Binding Cytoskeletal Protein Binding
	Biological Process	Cytoskeleton Organization Actin Filament Organization Regulation Of Endocytosis Negative Regulation Of Endocytosis Synaptic Vesicle Endocytosis Neuron Projection Morphogenesis Protein Localization To Membrane Establishment Of Protein Localization To Plasma Membrane Membrane Tubulation Positive Regulation Of Dendrite Development
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 22412388) Prostate cancer ( 18264098 19767753)
Protein-Protein Interactions		24 interactors: ANKRD24 ARHGAP17 ATP8 COBL COBLL1 DNM1 EHBP1 FTH1 GAS7 HTT JADE2 KAT7 KHDRBS1 PACSIN2 PACSIN3 POT1 RTKN2 SOS1 SPTBN1 SYNJ1 TPM4 TRPV4 WASF2 WASL	3 interactors: EHD1 EHD2 PACSIN1
Entrez ID		29993	23301
HPRD ID		05936	10109
Ensembl ID		ENSG00000124507	ENSG00000115504
Uniprot IDs		Q5TZC3 Q9BY11	A8K930 Q8NDI1
PDB IDs		3HAH 3HAI 3Q84 3QNI	2D89
Enriched GO Terms of Interacting Partners?		Cell Projection Morphogenesis Cell Part Morphogenesis Actin Filament-based Process Endocytosis Cellular Component Assembly Vesicle-mediated Transport Cell Morphogenesis Regulation Of Cellular Component Organization Organelle Organization Cytoskeleton Organization Cell Projection Organization Actin Cytoskeleton Organization Neuron Development Neuron Projection Morphogenesis Regulation Of Endocytosis Actin Filament-based Movement Endomembrane System Organization Generation Of Neurons Neuron Differentiation Histone H4-K12 Acetylation Membrane Tubulation Neurogenesis Neuron Projection Development Actin Polymerization Or Depolymerization Histone H4-K5 Acetylation Histone H4-K8 Acetylation Membrane Organization Axonogenesis Cell Development Enzyme Linked Receptor Protein Signaling Pathway Protein Polymerization Anatomical Structure Morphogenesis Axon Development Regulation Of Cellular Process Regulation Of Protein Depolymerization Positive Regulation Of Protein Depolymerization Actin Filament Organization Cell Morphogenesis Involved In Neuron Differentiation Membrane Assembly Regulation Of Cell Projection Assembly Regulation Of Protein Complex Disassembly Protein Complex Assembly Movement Of Cell Or Subcellular Component Cellular Protein Complex Assembly Membrane Biogenesis Cell Differentiation Regulation Of Vesicle-mediated Transport Positive Regulation Of Protein Complex Disassembly Cell Morphogenesis Involved In Differentiation Axon Guidance	Positive Regulation Of Endocytic Recycling Regulation Of Endocytic Recycling Positive Regulation Of Myoblast Fusion Regulation Of Myoblast Fusion Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Endocytic Recycling Regulation Of Vesicle-mediated Transport Positive Regulation Of Myotube Differentiation Regulation Of Myotube Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Endocytosis Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Muscle Cell Differentiation Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Cell Differentiation Regulation Of Muscle Cell Differentiation Protein Localization To Plasma Membrane Cellular Protein Localization Endosomal Transport Vesicle-mediated Transport Establishment Of Protein Localization Plasma Membrane Organization Establishment Of Protein Localization To Membrane Positive Regulation Of Intracellular Transport Regulation Of Cell Differentiation Protein Homooligomerization Protein Localization Regulation Of Cellular Component Organization Establishment Of Localization In Cell Protein Localization To Membrane Blood Coagulation Hemostasis Protein Oligomerization Regulation Of Intracellular Transport Endomembrane System Organization Regulation Of Cardiac Muscle Cell Membrane Potential Cellular Localization Positive Regulation Of Cholesterol Storage Regulation Of Body Fluid Levels Wound Healing Actin Cytoskeleton Organization Actin Filament-based Process Membrane Tubulation Low-density Lipoprotein Particle Clearance Response To Wounding Cellular Response To Nerve Growth Factor Stimulus Positive Regulation Of Transport Cortical Actin Cytoskeleton Organization Neuron Projection Development Positive Regulation Of Lipid Storage
Tagcloud ?		10a autophagic autophagosome autophagosomes bub1 catabolic cdkl3 csnk1a1 dapk2 endolysosomal flux functioned immortalized kinome macroautophagy maintains manipulation mcf mtorc1 nek4 pklr possibilities protects scyl1 shed sirnas starvation stresses wnk2	bcrp c9orf3 cassette cdyl chemotherapeutics chemotherapies conferred ctrl devised dock farnesol farnesylation farnesyltransferase foxa2 functionalized ine1 isoprenoid lmo7 mdr1 mrp1 mrs2 neb numbl oils oncoproteins pharmacogenomic sesquiterpene stab2 urgently
Tagcloud (Difference) ?		10a autophagic autophagosome autophagosomes bub1 catabolic cdkl3 csnk1a1 dapk2 endolysosomal flux functioned immortalized kinome macroautophagy maintains manipulation mcf mtorc1 nek4 pklr possibilities protects scyl1 shed sirnas starvation stresses wnk2	bcrp c9orf3 cassette cdyl chemotherapeutics chemotherapies conferred ctrl devised dock farnesol farnesylation farnesyltransferase foxa2 functionalized ine1 isoprenoid lmo7 mdr1 mrp1 mrs2 neb numbl oils oncoproteins pharmacogenomic sesquiterpene stab2 urgently
Tagcloud (Intersection) ?