PACSIN1 and ATP8

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		PACSIN1	ATP8
Gene Name		protein kinase C and casein kinase substrate in neurons 1	ATP synthase F0 subunit 8
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endosome Cytosol Plasma Membrane Membrane Cell Junction COPI-coated Vesicle Cytoplasmic Vesicle Membrane Membrane-bounded Vesicle Ruffle Membrane Neuron Projection Axon Terminus Synapse Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Phospholipid Binding Cytoskeletal Protein Binding
	Biological Process	Cytoskeleton Organization Actin Filament Organization Regulation Of Endocytosis Negative Regulation Of Endocytosis Synaptic Vesicle Endocytosis Neuron Projection Morphogenesis Protein Localization To Membrane Establishment Of Protein Localization To Plasma Membrane Membrane Tubulation Positive Regulation Of Dendrite Development
Pathways			Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. The citric acid (TCA) cycle and respiratory electron transport Formation of ATP by chemiosmotic coupling
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: ANKRD24 ARHGAP17 ATP8 COBL COBLL1 DNM1 EHBP1 FTH1 GAS7 HTT JADE2 KAT7 KHDRBS1 PACSIN2 PACSIN3 POT1 RTKN2 SOS1 SPTBN1 SYNJ1 TPM4 TRPV4 WASF2 WASL	4 interactors: GRB2 PACSIN1 RAPGEF2 WNK1
Entrez ID		29993	4509
HPRD ID		05936
Ensembl ID		ENSG00000124507
Uniprot IDs		Q5TZC3 Q9BY11	P03928 Q85BD0
PDB IDs		3HAH 3HAI 3Q84 3QNI
Enriched GO Terms of Interacting Partners?		Cell Projection Morphogenesis Cell Part Morphogenesis Actin Filament-based Process Endocytosis Cellular Component Assembly Vesicle-mediated Transport Cell Morphogenesis Regulation Of Cellular Component Organization Organelle Organization Cytoskeleton Organization Cell Projection Organization Actin Cytoskeleton Organization Neuron Development Neuron Projection Morphogenesis Regulation Of Endocytosis Actin Filament-based Movement Endomembrane System Organization Generation Of Neurons Neuron Differentiation Histone H4-K12 Acetylation Membrane Tubulation Neurogenesis Neuron Projection Development Actin Polymerization Or Depolymerization Histone H4-K5 Acetylation Histone H4-K8 Acetylation Membrane Organization Axonogenesis Cell Development Enzyme Linked Receptor Protein Signaling Pathway Protein Polymerization Anatomical Structure Morphogenesis Axon Development Regulation Of Cellular Process Regulation Of Protein Depolymerization Positive Regulation Of Protein Depolymerization Actin Filament Organization Cell Morphogenesis Involved In Neuron Differentiation Membrane Assembly Regulation Of Cell Projection Assembly Regulation Of Protein Complex Disassembly Protein Complex Assembly Movement Of Cell Or Subcellular Component Cellular Protein Complex Assembly Membrane Biogenesis Cell Differentiation Regulation Of Vesicle-mediated Transport Positive Regulation Of Protein Complex Disassembly Cell Morphogenesis Involved In Differentiation Axon Guidance	Neuron Development Neuron Differentiation Generation Of Neurons Neurogenesis Cell Development Nervous System Development Regulation Of Dendrite Development Neuron Projection Development Protein Localization To Plasma Membrane Negative Regulation Of Melanin Biosynthetic Process Cell Differentiation Cell Projection Organization Brain-derived Neurotrophic Factor Receptor Signaling Pathway Ras Protein Signal Transduction Plasma Membrane Organization Positive Regulation Of Neuron Projection Development Neurotrophin Signaling Pathway Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Positive Regulation Of Dendritic Cell Apoptotic Process Regulation Of Phosphorylation Negative Regulation Of Pancreatic Juice Secretion Positive Regulation Of CAMP-dependent Protein Kinase Activity Positive Regulation Of Cell Projection Organization Regulation Of Phosphorus Metabolic Process System Development Establishment Of Endothelial Intestinal Barrier Cellular Response To CGMP Positive Regulation Of Neuron Differentiation Response To CGMP Negative Regulation Of Dendrite Morphogenesis Protein Localization To Membrane Rap Protein Signal Transduction Regulation Of Neuron Projection Development Negative Regulation Of Transport Branching Involved In Labyrinthine Layer Morphogenesis Multicellular Organismal Development Positive Regulation Of Neurogenesis Intracellular Signal Transduction Anatomical Structure Development Endomembrane System Organization Regulation Of Cellular Component Organization Positive Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Vasculogenesis Nerve Growth Factor Signaling Pathway Regulation Of CAMP-dependent Protein Kinase Activity Cellular Response To Organonitrogen Compound Positive Regulation Of CAMP-mediated Signaling Positive Regulation Of Neuron Migration Regulation Of Cell Projection Organization Microvillus Assembly
Tagcloud ?		10a autophagic autophagosome autophagosomes bub1 catabolic cdkl3 csnk1a1 dapk2 endolysosomal flux functioned immortalized kinome macroautophagy maintains manipulation mcf mtorc1 nek4 pklr possibilities protects scyl1 shed sirnas starvation stresses wnk2	abolishing activators belongs chloroplasts coimmunoprecipitation cooperativity cox1 cytochrome deletion demonstrates disrupted entire entirely largest mitochondria motifs mrna mss51 oxidase pentatricopeptide pet309 polycistronic portion ppr predicts selectively translational undetectable utr
Tagcloud (Difference) ?		10a autophagic autophagosome autophagosomes bub1 catabolic cdkl3 csnk1a1 dapk2 endolysosomal flux functioned immortalized kinome macroautophagy maintains manipulation mcf mtorc1 nek4 pklr possibilities protects scyl1 shed sirnas starvation stresses wnk2	abolishing activators belongs chloroplasts coimmunoprecipitation cooperativity cox1 cytochrome deletion demonstrates disrupted entire entirely largest mitochondria motifs mrna mss51 oxidase pentatricopeptide pet309 polycistronic portion ppr predicts selectively translational undetectable utr
Tagcloud (Intersection) ?