Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
SIN3B and IKZF4
Number of citations of the paper that reports this interaction (PMID
12015313
)
17
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo)
SIN3B
IKZF4
Gene Name
SIN3 transcription regulator family member B
IKAROS family zinc finger 4 (Eos)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
X Chromosome
Y Chromosome
XY Body
Nucleus
Nucleoplasm
Cytoplasm
Sin3 Complex
Autosome
Nucleus
Molecular Function
RNA Polymerase II Transcription Corepressor Activity
Chromatin Binding
Histone Deacetylase Activity
Protein Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Homodimerization Activity
BHLH Transcription Factor Binding
Sequence-specific DNA Binding
Metal Ion Binding
Protein Heterodimerization Activity
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Skeletal Muscle Tissue Development
Histone Deacetylation
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Cardiac Muscle Tissue Development
Transcription, DNA-templated
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
NoRC negatively regulates rRNA expression
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Alopecia areata (
20596022
)
Asthma (
21804548
)
Type 1 diabetes (
18198356
)
Type 1 diabetes autoantibodies (
21829393
)
Vitiligo (
22561518
)
Protein-Protein Interactions
19 interactors:
COPS2
HDAC1
HDAC9
HIST3H3
IKZF1
IKZF4
MAD1L1
MXD1
MXI1
NR1D2
REST
RNF220
SETDB1
SMARCA2
SMARCA4
SMARCB1
SMARCE1
TP53
ZBTB16
12 interactors:
CHD4
FHL2
FOXP3
HDAC2
IKZF1
IKZF2
IKZF3
IKZF5
NFKBIA
NRG1
SIN3A
SIN3B
Entrez ID
23309
64375
HPRD ID
09691
05874
Ensembl ID
ENSG00000127511
ENSG00000123411
Uniprot IDs
O75182
G5E9S4
Q9H2S9
PDB IDs
2MA7
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Biosynthetic Process
Chromatin Organization
Chromosome Organization
RNA Metabolic Process
Chromatin Modification
Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Transcription From RNA Polymerase II Promoter
Cellular Nitrogen Compound Metabolic Process
Interaction With Symbiont
Positive Regulation Of Transcription, DNA-templated
Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
ATP-dependent Chromatin Remodeling
Chromatin Remodeling
Nucleosome Disassembly
Regulation Of Metabolic Process
Regulation Of Viral Transcription
Organelle Organization
Aortic Smooth Muscle Cell Differentiation
Histone H4 Deacetylation
Histone H3-K9 Modification
Positive Regulation Of NK T Cell Differentiation
Chromatin Assembly Or Disassembly
Multicellular Organismal Development
Hemopoiesis
Regulation Of Viral Process
Positive Regulation Of Cellular Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
RNA Metabolic Process
Chromatin Modification
Gene Expression
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Macromolecule Biosynthetic Process
Chromatin Organization
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Regulation Of Metabolic Process
Negative Regulation Of Biosynthetic Process
Cardiac Muscle Tissue Development
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Histone Deacetylation
Nucleobase-containing Compound Metabolic Process
Protein Deacetylation
Positive Regulation Of Cellular Biosynthetic Process
Chromosome Organization
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Striated Muscle Tissue Development
Muscle Tissue Development
Regulation Of Immune System Process
Cardiac Muscle Cell Differentiation
Nitrogen Compound Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cardiocyte Differentiation
Regulation Of Apoptotic Process
Regulation Of Cell Death
Negative Regulation Of Histone Acetylation
Negative Regulation Of Apoptotic Process
Positive Regulation Of Metabolic Process
Tagcloud
?
ablated
bcl6
conducive
cor
corepressors
deacteylases
erbaalpha
erbbeta
interactiondomains
laz3
locks
mad
mxi
physicalassociation
rev
rid
rids
rip13a
rip13delta1
rpd3
rvr
sin3a
tafii32
tafii70
tafs
terminalrepression
tfiib
zip
Tagcloud (Difference)
?
ablated
bcl6
conducive
cor
corepressors
deacteylases
erbaalpha
erbbeta
interactiondomains
laz3
locks
mad
mxi
physicalassociation
rev
rid
rids
rip13a
rip13delta1
rpd3
rvr
sin3a
tafii32
tafii70
tafs
terminalrepression
tfiib
zip
Tagcloud (Intersection)
?