SIN3B and RNF220

Number of citations of the paper that reports this interaction (PMID 20170641)
3

Data Source:
BioGRID (enzymatic study)

		SIN3B	RNF220
Gene Name		SIN3 transcription regulator family member B	ring finger protein 220
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	X Chromosome Y Chromosome XY Body Nucleus Nucleoplasm Cytoplasm Sin3 Complex Autosome	Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Corepressor Activity Chromatin Binding Histone Deacetylase Activity Protein Binding	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Skeletal Muscle Tissue Development Histone Deacetylation Cellular Lipid Metabolic Process Small Molecule Metabolic Process Cardiac Muscle Tissue Development	Protein Ubiquitination Protein Autoubiquitination
Pathways		NoRC negatively regulates rRNA expression Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: COPS2 HDAC1 HDAC9 HIST3H3 IKZF1 IKZF4 MAD1L1 MXD1 MXI1 NR1D2 REST RNF220 SETDB1 SMARCA2 SMARCA4 SMARCB1 SMARCE1 TP53 ZBTB16	4 interactors: GOPC SIN3B UBE2D3 USP7
Entrez ID		23309	55182
HPRD ID		09691	13336
Ensembl ID		ENSG00000127511	ENSG00000187147
Uniprot IDs		O75182	B4DLZ9 Q5VTB9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Chromatin Organization Chromosome Organization RNA Metabolic Process Chromatin Modification Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Interaction With Symbiont Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process ATP-dependent Chromatin Remodeling Chromatin Remodeling Nucleosome Disassembly Regulation Of Metabolic Process Regulation Of Viral Transcription Organelle Organization Aortic Smooth Muscle Cell Differentiation Histone H4 Deacetylation Histone H3-K9 Modification Positive Regulation Of NK T Cell Differentiation Chromatin Assembly Or Disassembly Multicellular Organismal Development Hemopoiesis Regulation Of Viral Process Positive Regulation Of Cellular Metabolic Process	Cytoplasmic Sequestering Of CFTR Protein Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Negative Regulation Of Golgi To Plasma Membrane Protein Transport Maintenance Of DNA Methylation Regulation Of Golgi To Plasma Membrane Protein Transport Histone Modification Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Apical Protein Localization Proteolysis Involved In Cellular Protein Catabolic Process Histone Deubiquitination Cellular Protein Catabolic Process Negative Regulation Of Protein Localization To Plasma Membrane DNA Repair Chromatin Modification Protein K11-linked Ubiquitination Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cytoplasmic Sequestering Of Protein Asymmetric Protein Localization Spermatid Nucleus Differentiation Chromatin Organization Golgi To Plasma Membrane Transport Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein K48-linked Ubiquitination Transcription-coupled Nucleotide-excision Repair Regulation Of Establishment Of Protein Localization To Plasma Membrane Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Cellular Macromolecule Catabolic Process Negative Regulation Of Type I Interferon Production Transcription From RNA Polymerase II Promoter Organelle Organization Regulation Of Protein Localization To Plasma Membrane Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cellular Protein Modification Process Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Metabolic Process Chromosome Organization TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Histone Deacetylation MyD88-independent Toll-like Receptor Signaling Pathway DNA Metabolic Process Toll-like Receptor 3 Signaling Pathway Protein Deacetylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription
Tagcloud ?		ablated bcl6 conducive cor corepressors deacteylases erbaalpha erbbeta interactiondomains laz3 locks mad mxi physicalassociation rev rid rids rip13a rip13delta1 rpd3 rvr sin3a tafii32 tafii70 tafs terminalrepression tfiib zip
Tagcloud (Difference) ?		ablated bcl6 conducive cor corepressors deacteylases erbaalpha erbbeta interactiondomains laz3 locks mad mxi physicalassociation rev rid rids rip13a rip13delta1 rpd3 rvr sin3a tafii32 tafii70 tafs terminalrepression tfiib zip
Tagcloud (Intersection) ?