SIN3B and MXI1

Number of citations of the paper that reports this interaction (PMID 15467743)
5

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		SIN3B	MXI1
Gene Name		SIN3 transcription regulator family member B	MAX interactor 1, dimerization protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	X Chromosome Y Chromosome XY Body Nucleus Nucleoplasm Cytoplasm Sin3 Complex Autosome	Nucleus Nucleolus Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Corepressor Activity Chromatin Binding Histone Deacetylase Activity Protein Binding	DNA Binding Transcription Corepressor Activity Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Skeletal Muscle Tissue Development Histone Deacetylation Cellular Lipid Metabolic Process Small Molecule Metabolic Process Cardiac Muscle Tissue Development	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Negative Regulation Of Cell Proliferation Cytoplasmic Sequestering Of Transcription Factor
Pathways		NoRC negatively regulates rRNA expression Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS			Normalized brain volume ( 19010793)
Protein-Protein Interactions		19 interactors: COPS2 HDAC1 HDAC9 HIST3H3 IKZF1 IKZF4 MAD1L1 MXD1 MXI1 NR1D2 REST RNF220 SETDB1 SMARCA2 SMARCA4 SMARCB1 SMARCE1 TP53 ZBTB16	16 interactors: APP CALCOCO2 ENTPD5 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 MAX MYC NOTCH2NL RPL23AP32 SIN3A SIN3B SMC3
Entrez ID		23309	4601
HPRD ID		09691	02486
Ensembl ID		ENSG00000127511	ENSG00000119950
Uniprot IDs		O75182	B1ANN8 P50539
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Chromatin Organization Chromosome Organization RNA Metabolic Process Chromatin Modification Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Interaction With Symbiont Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process ATP-dependent Chromatin Remodeling Chromatin Remodeling Nucleosome Disassembly Regulation Of Metabolic Process Regulation Of Viral Transcription Organelle Organization Aortic Smooth Muscle Cell Differentiation Histone H4 Deacetylation Histone H3-K9 Modification Positive Regulation Of NK T Cell Differentiation Chromatin Assembly Or Disassembly Multicellular Organismal Development Hemopoiesis Regulation Of Viral Process Positive Regulation Of Cellular Metabolic Process	Notch Signaling Pathway Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Transcription From RNA Polymerase II Promoter Neuron Apoptotic Process Regulation Of Cell Cycle Nucleobase-containing Compound Metabolic Process Histone Deacetylation Neuron Death Protein Deacetylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Chromosome Organization Response To Methylglyoxal Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Negative Regulation Of Histone H3-K27 Acetylation Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Stress Regulation Of Cell Cycle Process Synaptic Growth At Neuromuscular Junction Fibroblast Apoptotic Process Positive Regulation Of Mitotic Cell Cycle Developmental Process Nitrogen Compound Metabolic Process Cellular Chemical Homeostasis Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Collateral Sprouting In Absence Of Injury Positive Regulation Of Chromatin Silencing Chromatin Modification Positive Regulation Of Peptidase Activity Cell Growth Transition Metal Ion Homeostasis Cellular Response To Stress Cellular Homeostasis Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of DNA Endoreduplication Response To Wounding Chromatin Organization Negative Regulation Of Cell Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Monocyte Differentiation Axon Choice Point Recognition Positive Regulation Of Cell Proliferation Involved In Kidney Development
Tagcloud ?		ablated bcl6 conducive cor corepressors deacteylases erbaalpha erbbeta interactiondomains laz3 locks mad mxi physicalassociation rev rid rids rip13a rip13delta1 rpd3 rvr sin3a tafii32 tafii70 tafs terminalrepression tfiib zip	acting antagonizes b1 believed cdc2 cdk2 classic declined dramatically g2 glomerulonephritis gradually interactor inversely ki67 max mentioned mesangial myc nephritis obvious opposite percentage plasmid proliferation proliferative sirna thy1 transfection
Tagcloud (Difference) ?		ablated bcl6 conducive cor corepressors deacteylases erbaalpha erbbeta interactiondomains laz3 locks mad mxi physicalassociation rev rid rids rip13a rip13delta1 rpd3 rvr sin3a tafii32 tafii70 tafs terminalrepression tfiib zip	acting antagonizes b1 believed cdc2 cdk2 classic declined dramatically g2 glomerulonephritis gradually interactor inversely ki67 max mentioned mesangial myc nephritis obvious opposite percentage plasmid proliferation proliferative sirna thy1 transfection
Tagcloud (Intersection) ?