MXI1 and KRTAP5-7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MXI1	KRTAP5-7
Description		MAX interactor 1, dimerization protein	keratin associated protein 5-7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol RNA Polymerase II Transcription Regulator Complex	Cytosol Intermediate Filament
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Blastocyst Formation Regulation Of Transcription By RNA Polymerase II
Pathways			Keratinization
Drugs
Diseases
GWAS		Birth weight ( 31043758) Cutaneous malignant melanoma ( 32341527) Diastolic blood pressure ( 30224653) Neutrophil count ( 29403010 32888494) Normalized brain volume ( 19010793) Platelet count ( 29403010) Refractive error ( 32231278) White blood cell count ( 29403010 32888494)
Interacting Genes		30 interacting genes: APP CALCOCO2 CYSRT1 EFEMP2 ENTPD5 KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP5-7 MAX MDFI MYC NBPF19 NOTCH2NLA PEAR1 PRMT5 RPL23AP32 SIN3A SIN3B SMARCB1 SMC3 UBE2O USHBP1 ZNF655	70 interacting genes: ADAMTSL3 ADAMTSL4 CARD9 CD300LG COL8A1 CRCT1 CREB5 CRY2 CYSRT1 DMRT3 DOCK2 FAM161A GUCD1 HHEX HOXB9 IGFBP6 IGSF8 IL2RG ITGB5 KPRP KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-4 KRTAP5-6 KRTAP9-2 LCE1A LCE1B LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3D LCE3E LCE4A MACO1 MAPKBP1 MRGBP MXI1 MYOM1 PHLDA1 PTPMT1 RAMP3 SAMD11 SCARF1 SDC3 SHFL SLC39A7 SMCP SPATA3 TRIM42 UXT WNT11 ZNF330 ZNF440 ZNF479 ZNF587 ZNF613
Entrez ID		4601	440050
HPRD ID		02486	17251
Ensembl ID		ENSG00000119950	ENSG00000244411
Uniprot IDs		A0A0S2Z3X5 P50539	Q6L8G8
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Myc-Max Complex Epigenetic Regulation Of Gene Expression Structural Constituent Of Skin Epidermis E-box Binding Regulation Of Stem Cell Population Maintenance Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation XY Body	Epidermis Development Keratinization Intermediate Filament Keratin Filament Tissue Development Hair Cycle Protein Binding
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