MXI1 and ENTPD5

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		MXI1	ENTPD5
Name		MAX interactor 1, dimerization protein	ectonucleoside triphosphate diphosphohydrolase 5 (inactive)
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol RNA Polymerase II Transcription Regulator Complex	Extracellular Region Extracellular Space Endoplasmic Reticulum
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity	GDP Phosphatase Activity Protein Binding Hydrolase Activity Nucleoside Diphosphate Phosphatase Activity CDP Phosphatase Activity ADP Phosphatase Activity UDP Phosphatase Activity IDP Phosphatase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Blastocyst Formation Regulation Of Transcription By RNA Polymerase II	UDP-alpha-D-glucose Metabolic Process UDP Catabolic Process Protein Glycosylation Protein N-linked Glycosylation 'de Novo' Post-translational Protein Folding
Pathways		None	Phosphate bond hydrolysis by NTPDase proteins Purinergic signaling in leishmaniasis infection
GWAS		Birth weight ( 31043758 ) Cutaneous malignant melanoma ( 32341527 ) Diastolic blood pressure ( 30224653 ) Neutrophil count ( 29403010 32888494 ) Normalized brain volume ( 19010793 ) Platelet count ( 29403010 ) Refractive error ( 32231278 ) White blood cell count ( 29403010 32888494 )	Blood protein levels ( 30072576 ) Refractive error ( 32231278 ) Serum uric acid levels ( 29559957 )
Interacting Genes		30 interacting genes: APP CALCOCO2 CYSRT1 EFEMP2 ENTPD5 KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP5-7 MAX MDFI MYC NBPF19 NOTCH2NLA PEAR1 PRMT5 RPL23AP32 SIN3A SIN3B SMARCB1 SMC3 UBE2O USHBP1 ZNF655	2 interacting genes: MXI1 PRKCA
Entrez ID		4601	957
HPRD ID		02486	16015
Ensembl ID		ENSG00000119950	ENSG00000187097
Uniprot IDs		A0A0S2Z3X5 P50539	G3V4I0 O75356
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Keratin Filament Intermediate Filament Myc-Max Complex Epigenetic Regulation Of Gene Expression Structural Constituent Of Skin Epidermis E-box Binding Regulation Of Stem Cell Population Maintenance Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation XY Body	Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Angiotensin-activated Signaling Pathway Histone H3T6 Kinase Activity Alphav-beta3 Integrin-PKCalpha Complex Protein Kinase C Signaling Regulation Of Angiotensin-activated Signaling Pathway Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Desmosome Assembly Mitotic Nuclear Membrane Disassembly Diacylglycerol Binding Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Desmosome Organization Positive Regulation Of Bone Resorption Positive Regulation Of Macrophage Differentiation Membrane Disassembly Nuclear Membrane Disassembly Response To Phorbol 13-acetate 12-myristate Negative Regulation Of Glial Cell Apoptotic Process Response To Corticosterone Diacylglycerol-dependent Serine/threonine Kinase Activity Anatomical Structure Formation Involved In Morphogenesis Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Renal Sodium Ion Absorption Blastocyst Formation Renal Sodium Ion Transport Regulation Of Macrophage Differentiation Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of Platelet Aggregation Signal Transduction Involved In Regulation Of Gene Expression Regulation Of Bone Resorption Central Nervous System Neuron Axonogenesis Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Cytokine Production Involved In Inflammatory Response Response To Mineralocorticoid Regulation Of Bone Remodeling Renal Absorption Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Cytokine Production Involved In Inflammatory Response Nuclear Membrane Organization Regulation Of Platelet Activation