SCFD1 and DLST

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SCFD1	DLST
Gene Name		sec1 family domain containing 1	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Golgi-associated Vesicle Cis-Golgi Network Plasma Membrane Golgi Transport Complex SNARE Complex Golgi Cisterna Membrane	Nucleus Mitochondrial Matrix Membrane Oxoglutarate Dehydrogenase Complex Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Syntaxin Binding Protein N-terminus Binding	Dihydrolipoyllysine-residue Succinyltransferase Activity
	Biological Process	Cell Morphogenesis Response To Hypoxia Retrograde Vesicle-mediated Transport, Golgi To ER Post-Golgi Vesicle-mediated Transport Vesicle Docking Involved In Exocytosis Phagocytosis Response To Toxic Substance Protein Transport Regulation Of Protein Transport Regulation Of ER To Golgi Vesicle-mediated Transport Negative Regulation Of Autophagic Vacuole Assembly	Generation Of Precursor Metabolites And Energy Tricarboxylic Acid Cycle Lysine Catabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Small Molecule Metabolic Process
Pathways			Lysine catabolism Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Metabolism of amino acids and derivatives Citric acid cycle (TCA cycle)
Drugs
Diseases
GWAS			Non-small cell lung cancer ( 23144319)
Protein-Protein Interactions		5 interactors: DLST PPBP STX5 USO1 USP22	15 interactors: ARIH2 CCDC86 DLG5 FLII NAP1L1 NDRG1 OGDH PAK4 PFN2 RUSC2 SCFD1 TUBB4B UMPS ZBTB16 ZHX1
Entrez ID		23256	1743
HPRD ID		10210	00520
Ensembl ID		ENSG00000092108	ENSG00000119689
Uniprot IDs		Q8WVM8	B7Z6J1 P36957
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Fusion With Golgi Apparatus Vesicle Fusion Organelle Fusion Vesicle Docking Membrane Docking ER To Golgi Vesicle-mediated Transport Membrane Fusion Golgi Vesicle Docking Golgi Disassembly L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Vesicle Organization Golgi Vesicle Transport Golgi Inheritance Regulation Of Golgi Organization Lysine Catabolic Process Vesicle-mediated Transport Early Endosome To Golgi Transport Regulation Of Protein Catabolic Process Transcytosis Leukocyte Migration Involved In Inflammatory Response Histone Deubiquitination Acetyl-CoA Metabolic Process Establishment Of Localization In Cell Hexose Transmembrane Transport Histone Ubiquitination Cytoplasmic Transport Organelle Disassembly
Tagcloud ?			acneiform aphtha b51 began behcet believe chorioretinopathy deteriorate eruption erythema gradual granulomas granulomatous hypopyon infliximab interstitial nephritis nodosum november occasionally prednisolone psl reportedly sarcoidosis sometimes spasmodic stated transferred uveitis
Tagcloud (Difference) ?			acneiform aphtha b51 began behcet believe chorioretinopathy deteriorate eruption erythema gradual granulomas granulomatous hypopyon infliximab interstitial nephritis nodosum november occasionally prednisolone psl reportedly sarcoidosis sometimes spasmodic stated transferred uveitis
Tagcloud (Intersection) ?