SCFD1 and PPBP

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		SCFD1	PPBP
Description		sec1 family domain containing 1	pro-platelet basic protein
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Golgi-associated Vesicle Cis-Golgi Network Cytosol Membrane Golgi Cisterna Membrane	Extracellular Region Extracellular Space Platelet Alpha Granule Platelet Alpha Granule Lumen Tertiary Granule Lumen
	Molecular Function	Protein Binding Syntaxin Binding Protein-containing Complex Binding	Cytokine Activity Protein Binding Chemokine Activity Growth Factor Activity CXCR Chemokine Receptor Binding D-glucose Transmembrane Transporter Activity
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Post-Golgi Vesicle-mediated Transport Response To Toxic Substance Protein Transport Vesicle-mediated Transport Regulation Of Protein Transport Regulation Of ER To Golgi Vesicle-mediated Transport Negative Regulation Of Autophagosome Assembly	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Neutrophil Chemotaxis Killing Of Cells Of Another Organism Defense Response To Bacterium Positive Regulation Of Cell Division Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide D-glucose Transmembrane Transport
Pathways		COPII-mediated vesicle transport RHOA GTPase cycle	Platelet degranulation Chemokine receptors bind chemokines G alpha (i) signalling events Neutrophil degranulation
Drugs			Ethanesulfonic acid Copper
Diseases
GWAS		Amyotrophic lateral sclerosis ( 27455348 29566793) Cognitive decline (age-related) ( 28078323) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)	Metabolite levels ( 22916037)
Interacting Genes		5 interacting genes: DLST PPBP STX5 USO1 USP22	32 interacting genes: CCL13 CCL21 CCL26 CCL28 CCL5 CCL8 CELF1 CMTM6 COPG1 COPS7A COX17 CTSG CXCL10 CXCL11 CXCL12 CXCL14 CXCL6 CXCL9 CXCR1 CXCR2 DMWD EFNA1 MAPK6 MOB3B NDUFB11 NR4A1 PLEKHJ1 PMAIP1 RAB10 RPS27 SCFD1 STRN4
Entrez ID		23256	5473
HPRD ID		10210	07171
Ensembl ID		ENSG00000092108	ENSG00000163736
Uniprot IDs		A0A7I2V590 B7Z5N7 B7Z738 H0YIZ7 Q8WVM8	P02775
PDB IDs			1F9P 1NAP 1TVX
Enriched GO Terms of Interacting Partners?		Dihydrolipoyllysine-residue Succinyltransferase Activity ER To Golgi Transport Vesicle Membrane Vesicle Docking Organelle Localization By Membrane Tethering Membrane Docking Golgi Vesicle Docking Vesicle Fusion Organelle Membrane Fusion Golgi Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Organelle Fusion L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Oxoadipate Dehydrogenase Complex L-lysine Catabolic Process Membrane Fusion Histone H2B Deubiquitinase Activity Lysine Catabolic Process Oxoglutarate Dehydrogenase Complex Golgi Disassembly Positive Regulation Of Protein Catabolic Process Vesicle Fusion With Golgi Apparatus Histone H2A Deubiquitinase Activity Succinyl-CoA Metabolic Process D-glucose Transmembrane Transporter Activity Golgi Vesicle Transport Histone H4 Acetyltransferase Activity Amide Catabolic Process CXCR Chemokine Receptor Binding Vesicle Organization Cadherin Binding 2-oxoglutarate Metabolic Process Platelet Alpha Granule Early Endosome To Golgi Transport Regulation Of Golgi Organization Bounding Membrane Of Organelle Regulation Of Protein Catabolic Process Transcytosis Transcription Factor TFTC Complex	Chemokine Activity Cell Chemotaxis Leukocyte Chemotaxis Chemokine-mediated Signaling Pathway Chemotaxis Locomotion Antimicrobial Humoral Response Granulocyte Chemotaxis Leukocyte Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Myeloid Leukocyte Migration Granulocyte Migration Humoral Immune Response Cytokine Activity Killing Of Cells Of Another Organism Cell Migration Cytokine-mediated Signaling Pathway Mononuclear Cell Migration Cell Motility Cell Killing CXCR Chemokine Receptor Binding Inflammatory Response Eosinophil Chemotaxis Defense Response To Symbiont Eosinophil Migration Defense Response Defense Response To Other Organism Immune System Process Neutrophil Chemotaxis Immune Response CCR Chemokine Receptor Binding Chemokine Receptor Binding Neutrophil Migration Response To External Biotic Stimulus Response To Other Organism Cell-cell Signaling G Protein-coupled Receptor Signaling Pathway Signaling Cell Communication T Cell Chemotaxis Dendritic Cell Chemotaxis Negative Regulation Of Leukocyte Tethering Or Rolling CXCR3 Chemokine Receptor Binding Dendritic Cell Migration Lymphocyte Chemotaxis Neutrophil Activation Negative Regulation Of Cellular Extravasation T Cell Migration Positive Regulation Of T Cell Migration Extracellular Space
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