PLEKHM2 and KLC1

Number of citations of the paper that reports this interaction (PubMedID 15905402)
0

Data Source:
HPRD (in vitro)

		PLEKHM2	KLC1
Description		pleckstrin homology and RUN domain containing M2	kinesin light chain 1
Image
GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Endosome Membrane Membrane	Cytoplasm Cytosol Cytoskeleton Kinesin Complex Microtubule Membrane Growth Cone Cytoplasmic Vesicle Cell Projection
	Molecular Function	Protein Binding Kinesin Binding	Cytoskeletal Motor Activity Protein Binding Kinesin Binding
	Biological Process	Golgi Organization Lysosome Localization Regulation Of Protein Localization Natural Killer Cell Mediated Cytotoxicity	Microtubule-based Movement Cell Adhesion Stress Granule Disassembly
Pathways			MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Signaling by ALK fusions and activated point mutants Kinesins
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Estimated glomerular filtration rate ( 31015462)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 25673413 28892062) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 25056061) Smoking behaviour (cigarette pack-years) ( 30679032) Urate levels ( 31578528)
Interacting Genes		2 interacting genes: KLC1 SLC39A1	29 interacting genes: ADRB2 AP1AR APP ATCAY BNIP2 CLSTN1 ERBB2 F2RL1 HSPB1 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 NIN ODAD1 ODF1 PCM1 PLEKHM2 PTGER4 SNCA SPAG9 TACC3 TSC1 YWHAB
Entrez ID		23207	3831
HPRD ID		11440	02489
Ensembl ID		ENSG00000116786	ENSG00000126214
Uniprot IDs		Q8IWE5	F8W6L3 G3V2E7 G3V3H3 G3V5R9 G5E9S8 Q07866 Q7RTQ2
PDB IDs		3CXB 3HW2 3ZFW 8JCA	3NF1 5OJ8 7AI4 7AIE
Enriched GO Terms of Interacting Partners?		Stress Granule Disassembly Inorganic Cation Transmembrane Transporter Activity Embryonic Cranial Skeleton Morphogenesis Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Metal Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Kinesin Complex Kinesin Binding Cytoskeletal Motor Activity Limb Development Organelle Disassembly Embryonic Skeletal System Morphogenesis	Kinesin Binding MAP-kinase Scaffold Activity JUN Kinase Binding Protein Localization To Synapse Positive Regulation Of MAPK Cascade Microtubule-based Process Perinuclear Region Of Cytoplasm Microtubule-based Movement Protein Localization To Cell Junction Anterograde Axonal Protein Transport Protein Transport Along Microtubule Organelle Localization Regulation Of MAPK Cascade MAPK Cascade Regulation Of JNK Cascade Cytoskeleton Positive Regulation Of Cell Communication Positive Regulation Of Signaling Cell Projection Axonal Growth Cone Axo-dendritic Transport Transport Along Microtubule Ciliary Basal Body Lysosome Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of JNK Cascade Microtubule-based Transport Regulation Of Supramolecular Fiber Organization Protein-containing Complex Leukocyte Activation Anterograde Axonal Transport Protein Kinase Inhibitor Activity Kinesin Complex Axon Modulation Of Excitatory Postsynaptic Potential Receptor Localization To Synapse Positive Regulation Of Signal Transduction Centriolar Subdistal Appendage Mitotic Spindle Growth Cone Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Cell Projection Organization Intracellular Signaling Cassette Lysosome Localization Microtubule Anchoring At Centrosome Regulation Of G Protein-coupled Receptor Signaling Pathway Cytoplasm Cell Activation JNK Cascade
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?