PLEKHM2 and KLC1

Number of citations of the paper that reports this interaction (PMID 15905402)
57

Data Source:
HPRD (in vitro)

		PLEKHM2	KLC1
Gene Name		pleckstrin homology domain containing, family M (with RUN domain) member 2	kinesin light chain 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm	Cytosol Kinesin Complex Microtubule Membrane Cytoplasmic Membrane-bounded Vesicle Axon Growth Cone Ciliary Rootlet Neuronal Cell Body
	Molecular Function	Protein Binding Kinesin Binding	Motor Activity Microtubule Motor Activity Protein Binding Tubulin Binding
	Biological Process	Golgi Organization	Intracellular Protein Transport Microtubule-based Movement Blood Coagulation Axon Cargo Transport Metabolic Process Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Protein Localization To Synapse Stress Granule Disassembly
Pathways			MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: KLC1 SLC39A1	18 interactors: APP BNIP2 CCDC114 CLSTN1 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 ODF1 PLEKHM2 SNCA SPAG9 YWHAB
Entrez ID		23207	3831
HPRD ID		11440	02489
Ensembl ID		ENSG00000116786	ENSG00000126214
Uniprot IDs		Q5VVD7 Q8IWE5	F8W6L3 G3V2E7 G3V3H3 G3V5R9 Q07866 Q7RTQ2
PDB IDs		3CXB 3HW2 3ZFW	3NF1
Enriched GO Terms of Interacting Partners?		Stress Granule Disassembly Protein Localization To Synapse Zinc Ion Transmembrane Transport Zinc Ion Transport Organelle Disassembly Axon Cargo Transport	MAPK Cascade Signal Transduction By Phosphorylation JNK Cascade Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Regulation Of Phosphorylation Regulation Of MAPK Cascade Regulation Of Phosphorus Metabolic Process Regulation Of JNK Cascade Regulation Of Protein Phosphorylation Regulation Of Stress-activated MAPK Cascade Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Positive Regulation Of Phosphorylation Phosphorylation Regulation Of JUN Kinase Activity Positive Regulation Of Transferase Activity Cell Morphogenesis Involved In Neuron Differentiation Microtubule-based Movement Positive Regulation Of Catalytic Activity Generation Of Neurons Neuron Projection Morphogenesis Positive Regulation Of Cellular Protein Metabolic Process Neurogenesis Nervous System Development Positive Regulation Of Stress-activated MAPK Cascade Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Cell Morphogenesis Involved In Differentiation Positive Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Axon Guidance Positive Regulation Of Protein Metabolic Process Microtubule-based Process Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Neuron Projection Development Mating Behavior Cell Projection Morphogenesis Cell Differentiation Regulation Of Cellular Protein Metabolic Process Cell Part Morphogenesis Response To Stress Activation Of JUN Kinase Activity Positive Regulation Of Protein Modification Process Vesicle-mediated Transport Regulation Of Signal Transduction
Tagcloud ?		accounted attenuating effector enterica hydrolytic lysosomal lysosome lysosomes mannose mpr mprs noninfected pathogen potency rab9 replicates retrograde salmonella sequestration sifa skip subverted thereby trafficking translocated transported undergo vacuoles whose	amyloidogenesis amyloidogenic arise axonal cargos causal collectively concepts controversial defects dysregulation impairs implicate implicates inevitably kinesin klc1ve modifier morihara neurodegeneration perpetuates reciprocal secretory splice splicing transport triggers unbiased vicious
Tagcloud (Difference) ?		accounted attenuating effector enterica hydrolytic lysosomal lysosome lysosomes mannose mpr mprs noninfected pathogen potency rab9 replicates retrograde salmonella sequestration sifa skip subverted thereby trafficking translocated transported undergo vacuoles whose	amyloidogenesis amyloidogenic arise axonal cargos causal collectively concepts controversial defects dysregulation impairs implicate implicates inevitably kinesin klc1ve modifier morihara neurodegeneration perpetuates reciprocal secretory splice splicing transport triggers unbiased vicious
Tagcloud (Intersection) ?