Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
FAF2 and NF1
Number of citations of the paper that reports this interaction (PMID
20160012
)
14
Data Source:
BioGRID
(enzymatic study)
FAF2
NF1
Gene Name
Fas associated factor family member 2
neurofibromin 1
Image
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum
Lipid Particle
Cdc48p-Npl4p-Ufd1p AAA ATPase Complex
Intracellular Membrane-bounded Organelle
Nucleus
Nucleolus
Cytoplasm
Membrane
Axon
Dendrite
Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane
Molecular Function
Protein Binding
Ubiquitin Protein Ligase Binding
Lipase Binding
Ubiquitin Binding
Lipase Inhibitor Activity
Ras GTPase Activator Activity
Protein Binding
Phosphatidylethanolamine Binding
Phosphatidylcholine Binding
Biological Process
Response To Unfolded Protein
Lipid Particle Organization
Negative Regulation Of Catalytic Activity
MAPK Cascade
Osteoblast Differentiation
Metanephros Development
Response To Hypoxia
Liver Development
Negative Regulation Of Endothelial Cell Proliferation
Positive Regulation Of Endothelial Cell Proliferation
Regulation Of Cell-matrix Adhesion
Negative Regulation Of Cell-matrix Adhesion
Negative Regulation Of Protein Kinase Activity
Cell Communication
Ras Protein Signal Transduction
Negative Regulation Of Neuroblast Proliferation
Brain Development
Peripheral Nervous System Development
Heart Development
Skeletal Muscle Tissue Development
Visual Learning
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Schwann Cell Development
Phosphatidylinositol 3-kinase Signaling
Negative Regulation Of Angiogenesis
Spinal Cord Development
Forebrain Astrocyte Development
Neural Tube Development
Cerebral Cortex Development
Myelination In Peripheral Nervous System
Actin Cytoskeleton Organization
Extracellular Matrix Organization
Collagen Fibril Organization
Adrenal Gland Development
Negative Regulation Of Cell Migration
Regulation Of Synaptic Transmission, GABAergic
Regulation Of Ras GTPase Activity
Positive Regulation Of Ras GTPase Activity
Negative Regulation Of Rac Protein Signal Transduction
Wound Healing
Negative Regulation Of Transcription Factor Import Into Nucleus
Positive Regulation Of Apoptotic Process
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of MAPK Cascade
Pigmentation
Positive Regulation Of Neuron Apoptotic Process
Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Bone Resorption
Negative Regulation Of Osteoclast Differentiation
Regulation Of Glial Cell Differentiation
Positive Regulation Of Adenylate Cyclase Activity
Regulation Of Angiogenesis
Negative Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Neurotransmitter Secretion
Negative Regulation Of Fibroblast Proliferation
Regulation Of Long-term Neuronal Synaptic Plasticity
Sympathetic Nervous System Development
Camera-type Eye Morphogenesis
Negative Regulation Of Astrocyte Differentiation
Negative Regulation Of Oligodendrocyte Differentiation
Smooth Muscle Tissue Development
Artery Morphogenesis
Forebrain Morphogenesis
Cognition
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
7 interactors:
FAF1
FAS
NF1
PNPLA2
PSMD2
UBE2D1
UBQLN2
13 interactors:
APP
DNAJC7
FAF2
GRIN1
GRIN2D
HRAS
MYOG
SDC2
SMAD2
SMAD3
SMAD4
TBPL1
VCP
Entrez ID
23197
4763
HPRD ID
16870
01203
Ensembl ID
ENSG00000113194
ENSG00000196712
Uniprot IDs
Q96CS3
P21359
PDB IDs
2DAM
1NF1
2D4Q
2E2X
3P7Z
3PEG
3PG7
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Cellular Protein Metabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Positive Regulation Of Proteolysis
Regulation Of Protein Metabolic Process
Negative Regulation Of Transferase Activity
Apoptotic Process
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Programmed Cell Death
Cell Death
Death
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Catalytic Activity
Negative Regulation Of Transcription Factor Import Into Nucleus
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Protein Catabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Signal Transduction
Negative Regulation Of Protein Import Into Nucleus
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Negative Regulation Of Protein Localization To Nucleus
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Regulation Of Apoptotic Process
Negative Regulation Of Intracellular Protein Transport
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Transcription Factor Import Into Nucleus
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Catalytic Activity
Triglyceride Metabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Regulation Of Cell Death
Forebrain Astrocyte Development
Cellular Protein Catabolic Process
Negative Regulation Of Protein Ubiquitination
Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
SMAD Protein Complex Assembly
Response To Abiotic Stimulus
Cell Development
Regulation Of Cell Development
Regulation Of Cell Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Epithelial To Mesenchymal Transition
Response To Organic Substance
Axon Guidance
Cellular Component Assembly
Regulation Of Cellular Component Organization
Ionotropic Glutamate Receptor Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Stem Cell Differentiation
SMAD Protein Signal Transduction
Regulation Of Epithelial To Mesenchymal Transition
Regulation Of Cell Morphogenesis
Enzyme Linked Receptor Protein Signaling Pathway
Primary MiRNA Processing
Positive Regulation Of Macromolecule Biosynthetic Process
Visual Learning
Glutamate Receptor Signaling Pathway
DNA-templated Transcription, Initiation
Positive Regulation Of Gene Expression
Axonogenesis
Visual Behavior
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Binding
Cellular Response To Growth Factor Stimulus
Protein Complex Assembly
Axon Development
Endoderm Development
Anatomical Structure Morphogenesis
Cell Morphogenesis Involved In Neuron Differentiation
Embryonic Pattern Specification
Response To Growth Factor
Cell Differentiation
Regulation Of Transforming Growth Factor Beta2 Production
Paraxial Mesoderm Morphogenesis
Chemotaxis
Developmental Growth
Associative Learning
Positive Regulation Of Cellular Metabolic Process
Neuron Projection Morphogenesis
Response To External Stimulus
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cell Proliferation
Ephrin Receptor Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Cell Morphogenesis Involved In Differentiation
Tagcloud
?
american
artiodactyla
assigned
block
blot
cattle
chr
conservative
conserved
cow
electrophoresis
erbb2
hybrid
hybridization
localization
localized
means
mink
pepa
pig
prkca
rara
representatives
sheep
southern
swine
synteny
tk1
umph2
Tagcloud (Difference)
?
american
artiodactyla
assigned
block
blot
cattle
chr
conservative
conserved
cow
electrophoresis
erbb2
hybrid
hybridization
localization
localized
means
mink
pepa
pig
prkca
rara
representatives
sheep
southern
swine
synteny
tk1
umph2
Tagcloud (Intersection)
?