STAB1 and GGA3

Number of citations of the paper that reports this interaction (PubMedID 15345724)
0

Data Source:
BioGRID (pull down)

		STAB1	GGA3
Description		stabilin 1	golgi associated, gamma adaptin ear containing, ARF binding protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Endocytic Vesicle Membrane	Lysosome Endosome Early Endosome Golgi Apparatus Trans-Golgi Network Endosome Membrane Membrane Early Endosome Membrane Protein-containing Complex Recycling Endosome Recycling Endosome Membrane
	Molecular Function	Low-density Lipoprotein Particle Receptor Activity Scavenger Receptor Activity Calcium Ion Binding Protein Binding Hyaluronic Acid Binding Protein-disulfide Reductase Activity Low-density Lipoprotein Particle Binding	Protein Binding Small GTPase Binding Phosphatidylinositol Binding Ubiquitin Binding Protein-containing Complex Binding Protein Transporter Activity
	Biological Process	Endocytosis Receptor-mediated Endocytosis Inflammatory Response Cell Adhesion Cell-cell Signaling Negative Regulation Of Angiogenesis Defense Response To Bacterium	Protein Targeting To Lysosome Intracellular Protein Transport Golgi To Plasma Membrane Transport Protein Transport Vesicle-mediated Transport Protein Catabolic Process Regulation Of Protein Stability Protein Destabilization Endocytic Recycling Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport Positive Regulation Of Protein Catabolic Process Protein Localization To Lysosome Negative Regulation Of Amyloid-beta Formation Positive Regulation Of Lysosomal Protein Catabolic Process
Pathways		Scavenging by Class H Receptors	TBC/RABGAPs MET receptor recycling Amyloid fiber formation
Drugs
Diseases
GWAS		A body shape index ( 34021172) Adiponectin levels ( 31178129) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Colon cancer ( 33632709) Cortical surface area (MOSTest) ( 32665545) Distal colorectal cancer ( 33632709) Diverticular disease ( 30177863) HDL cholesterol ( 24097068) HDL cholesterol levels ( 28334899) Height ( 31562340) Hematocrit ( 27863252) Hodgkin's lymphoma ( 34216518) Intelligence (MTAG) ( 29326435) Iron status biomarkers (ferritin levels) ( 33536631) Parkinson's disease ( 28892059) Schizophrenia ( 29483656 25056061 23974872) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary albumin-to-creatinine ratio ( 31511532) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-hip ratio ( 20935629) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		8 interacting genes: CHID1 DYRK1A GGA1 GGA2 GGA3 NUFIP2 ORC5 PIK3R2	45 interacting genes: ADRA2A ADRA2B AFTPH AP1G1 AP1S2 ARAP3 ARF1 ARF3 CDKN2A CLINT1 CLTC CYTH2 DAZAP2 EGFR ETS1 GGA1 GGA2 GTPBP4 IGF2R LITAF LRP10 M6PR NPM1 P4HA3 PACS1 PLEKHB2 PTGDR PTGDS RABEP1 RNF11 RNF214 RPS27A STAB1 SYNRG TBC1D3 TOLLIP TP53 TRAPPC6A TRIM23 TSG101 UBC UPRT VPS11 VPS18 ZNF497
Entrez ID		23166	23163
HPRD ID		09778	10443
Ensembl ID		ENSG00000010327	ENSG00000125447
Uniprot IDs		Q9NY15	A8K6M0 B7Z456 Q9NZ52
PDB IDs			1JPL 1JUQ 1LF8 1P4U 1WR6 1YD8
Enriched GO Terms of Interacting Partners?		Golgi To Plasma Membrane Protein Transport Protein Localization To Cell Surface Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Plasma Membrane Trans-Golgi Network Golgi To Plasma Membrane Transport Ubiquitin Binding Post-Golgi Vesicle-mediated Transport Phosphatidylinositol Binding Vesicle-mediated Transport To The Plasma Membrane Localization Within Membrane Intracellular Protein Transport Protein Localization To Plasma Membrane Early Endosome Membrane Regulation Of Amyloid-beta Formation Protein Transport Protein Localization To Cell Periphery Regulation Of Amyloid Precursor Protein Catabolic Process Histone H3T45 Kinase Activity Establishment Of Protein Localization Endosome Membrane Small GTPase Binding Golgi Vesicle Transport Protein Localization To Membrane Regulation Of Amide Metabolic Process Actin Filament Ribonucleoprotein Complex Regulation Of Supramolecular Fiber Organization Endoplasmic Reticulum Signal Peptide Binding Regulation Of Protein-containing Complex Assembly Negative Regulation Of Heterochromatin Formation Negative Regulation Of Protein-containing Complex Assembly Regulation Of Neurofibrillary Tangle Assembly Splicing Factor Binding Origin Recognition Complex Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Intracellular Protein Localization Regulation Of Actin Filament Length 1-phosphatidylinositol-3-kinase Regulator Activity Signal Recognition Particle SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Box C/D Methylation Guide SnoRNP Complex Regulation Of Microvillus Length Anion Binding Positive Regulation Of Lysosomal Protein Catabolic Process Regulation Of Cytoskeleton Organization Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Supramolecular Fiber Organization 7S RNA Binding	Vesicle-mediated Transport Intracellular Protein Transport Cellular Localization Clathrin-coated Vesicle Endosome Establishment Of Localization In Cell Intracellular Transport Protein Transport Establishment Of Protein Localization Endosome Membrane Intracellular Protein Localization Early Endosome Golgi Apparatus AP-1 Adaptor Complex Endocytosis Trans-Golgi Network Membrane Trans-Golgi Network Lysosomal Transport Early Endosome Membrane Perinuclear Region Of Cytoplasm Import Into Cell Vacuolar Transport Autophagy Ubiquitin Protein Ligase Binding Endosome To Lysosome Transport Alpha2-adrenergic Receptor Activity Protein-containing Complex Golgi Membrane Protein Localization To Organelle Clathrin-coated Endocytic Vesicle Membrane Endocytic Vesicle Clathrin-coated Pit Disordered Domain Specific Binding Lysosomal Membrane Late Endosome Endomembrane System Negative Regulation Of Epinephrine Secretion Golgi Vesicle Transport Negative Regulation Of Norepinephrine Secretion Epinephrine Binding Clathrin Coat Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Clathrin Coat Of Trans-Golgi Network Vesicle CORVET Complex Ubiquitin Binding Post-Golgi Vesicle-mediated Transport Vesicle Organization Protein Localization To Ciliary Membrane Regulation Of Uterine Smooth Muscle Contraction Adrenergic Receptor Activity
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