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CLASP1
Description
cytoplasmic linker associated protein 1
Image
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Kinetochore
Chromosome
Cytoplasm
Golgi Apparatus
Centrosome
Microtubule Organizing Center
Spindle
Kinetochore Microtubule
Cytosol
Cytoskeleton
Microtubule
Spindle Microtubule
Cytoplasmic Microtubule
Focal Adhesion
Cell Cortex
Membrane
Cortical Microtubule Cytoskeleton
Centrosomal Corona
Microtubule Plus-end
Basal Cortex
Mitotic Spindle
Molecular Function
Dystroglycan Binding
Protein Binding
Microtubule Binding
Tubulin Binding
Kinetochore Binding
Microtubule Plus-end Binding
Biological Process
Microtubule Cytoskeleton Organization
Microtubule Bundle Formation
Vesicle Targeting
Microtubule Nucleation
Negative Regulation Of Microtubule Depolymerization
Golgi Organization
Mitotic Spindle Organization
Establishment Or Maintenance Of Cell Polarity
Exit From Mitosis
Regulation Of Gastrulation
Positive Regulation Of Epithelial Cell Migration
Regulation Of Epithelial To Mesenchymal Transition
Establishment Of Cell Polarity
Astral Microtubule Organization
Microtubule Organizing Center Organization
Negative Regulation Of Microtubule Polymerization Or Depolymerization
Positive Regulation Of Microtubule Polymerization
Microtubule Anchoring
Establishment Of Mitotic Spindle Localization
Positive Regulation Of Exocytosis
Establishment Of Spindle Orientation
Cell Division
Negative Regulation Of Stress Fiber Assembly
Regulation Of Focal Adhesion Assembly
Basement Membrane Organization
Positive Regulation Of Extracellular Matrix Disassembly
Mitotic Spindle Assembly
Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells
Positive Regulation Of Basement Membrane Assembly Involved In Embryonic Body Morphogenesis
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Role of ABL in ROBO-SLIT signaling
Anchoring of the basal body to the plasma membrane
RHO GTPases Activate Formins
Mitotic Prometaphase
AURKA Activation by TPX2
EML4 and NUDC in mitotic spindle formation
Drugs
Fostamatinib
Diseases
GWAS
Chloride levels (
29403010
)
Cough in response to angiotensin-converting enzyme inhibitor drugs (
28084903
)
HDL cholesterol x physical activity interaction (1df test) (
30670697
)
HDL cholesterol x physical activity interaction (2df test) (
30670697
)
Low density lipoprotein cholesterol levels (
32154731
)
Metabolite levels (
23823483
)
Potassium levels (
29403010
)
Triglyceride levels (
32154731
)
Novel Interacting Genes
1 novel interacting genes:
PRKRA
Interacting Genes
12 interacting genes:
CEBPA
CKAP5
EIF4ENIF1
JAKMIP2
MAP4
MAPRE1
MAPRE3
MARK3
MTNR1A
MTNR1B
SRPK2
YWHAG
Entrez ID
23332
HPRD ID
09322
Ensembl ID
ENSG00000074054
Uniprot IDs
A0A8V8TLP7
A0A8V8TRF6
Q7Z460
PDB IDs
4K92
6MQ5
6MQ7
Enriched GO Terms of Interacting Partners
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Microtubule Binding
Microtubule Polymerization
Microtubule Plus-end
Microtubule Plus-end Binding
Mitotic Spindle Astral Microtubule End
Microtubule Polymerization Or Depolymerization
Melatonin Receptor Activity
Spindle Organization
Microtubule Cytoskeleton Organization
Regulation Of Microtubule Polymerization
Protein Polymerization
Microtubule Cytoskeleton
Microtubule Organizing Center
Protein Localization To Microtubule
Kinase Binding
Regulation Of Microtubule Polymerization Or Depolymerization
Microtubule Cytoskeleton Organization Involved In Mitosis
Protein Serine/threonine Kinase Binding
Organelle Organization
Spindle Midzone
Microtubule-based Process
Regulation Of Microtubule Cytoskeleton Organization
Cell Division
Positive Regulation Of Microtubule Polymerization
RNA Binding
Establishment Of Spindle Orientation
Cytoskeleton Organization
Protein Localization To Cytoskeleton
RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Microtubule Plus End Polymerase
Protein Localization To Astral Microtubule
Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
Establishment Of Spindle Localization
Cellular Component Assembly
Cytoplasmic Microtubule
Regulation Of Microtubule-based Process
Tubulin Binding
Spindle Localization
Protein Localization To Organelle
Membraneless Organelle Assembly
Response To Vitamin B2
C/EBP Complex
Negative Regulation Of Non-motile Cilium Assembly
Microtubule Stabilizing Activity
Ciliary Basal Body
Protein Localization To Mitotic Spindle
Protein Localization To Spindle Microtubule
Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
Protein-containing Complex Assembly
Tagcloud
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