CLASP1

Gene Name		cytoplasmic linker associated protein 1
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Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Golgi Apparatus Centrosome Kinetochore Microtubule Cytosol Spindle Microtubule Cytoplasmic Microtubule Cell Cortex Membrane Cortical Microtubule Cytoskeleton Centrosomal Corona Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Microtubule Binding Kinetochore Binding Microtubule Plus-end Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Bundle Formation Organelle Organization Microtubule Nucleation Negative Regulation Of Microtubule Depolymerization Establishment Or Maintenance Of Cell Polarity Axon Guidance Exit From Mitosis Microtubule Organizing Center Organization Negative Regulation Of Microtubule Polymerization Or Depolymerization Microtubule Anchoring Establishment Of Spindle Orientation Cell Division
Pathways		Role of Abl in Robo-Slit signaling Mitotic Prometaphase Organelle biogenesis and maintenance Axon guidance Separation of Sister Chromatids Assembly of the primary cilium G2/M Transition Mitotic Anaphase Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane M Phase Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Loss of Nlp from mitotic centrosomes Centrosome maturation Signaling by Robo receptor Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: CLIP2 JAKMIP2 MAPRE1 MAPRE3 YWHAG
Entrez ID		23332
HPRD ID		09322
Ensembl ID		ENSG00000074054
Uniprot IDs		A2RU21 B7ZLX3 Q7Z460
PDB IDs		4K92
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Microtubule Plus-end Binding Positive Regulation Of Protein Binding Mitotic Cell Cycle Process Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Binding Cell Cycle Process Regulation Of Protein Binding Cell Cycle Regulation Of Binding Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Nuclear Division Protein Localization To Microtubule Cell Division Negative Regulation Of Microtubule Polymerization Organelle Organization Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Localization To Cytoskeleton Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Microtubule Polymerization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Organelle Organization Regulation Of Protein Phosphorylation Negative Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of Mitochondrion Organization Regulation Of Phosphorylation Regulation Of Microtubule Polymerization Or Depolymerization Cellular Protein Localization Negative Regulation Of Protein Polymerization Regulation Of Phosphorus Metabolic Process Regulation Of Mitochondrion Organization Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Tagcloud ?		clip1 cranial cytoskeleton ectoderm ectodermal embryogenesis gastrulation glued hemisphere involuting laevis lis1 maternally mesoderm microtubule microtubules movements nerves neurogenesis p150 persists platforms progresses stim1 tip tips tracking vertebrate xenopus