MAPRE1 and TROAP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MAPRE1	TROAP
Gene Name		microtubule-associated protein, RP/EB family, member 1	trophinin associated protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Centrosome Spindle Cytosol Microtubule Cytoplasmic Microtubule Cortical Microtubule Cytoskeleton Cell Projection Membrane Microtubule Plus-end	Cytoplasm
	Molecular Function	Protein Binding Protein C-terminus Binding Poly(A) RNA Binding Microtubule Plus-end Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Cell Proliferation Negative Regulation Of Microtubule Polymerization Protein Localization To Microtubule Cell Division Positive Regulation Of Microtubule Plus-end Binding	Cell Adhesion
Pathways		Mitotic Prometaphase Organelle biogenesis and maintenance Separation of Sister Chromatids Assembly of the primary cilium G2/M Transition Mitotic Anaphase Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane M Phase Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Loss of Nlp from mitotic centrosomes Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: ABCB1 APC APC2 APP AURKB BCL3 CDK5RAP2 CLASP1 CLASP2 CLIP1 COPS5 COPS8 CSN3 CYLD DCTN1 HSPA1A IKBKG KAT2B KAT5 KIF2C LMO2 LRP1 MACF1 MAPRE2 MAPRE3 NAV1 NUPR1 PDE4DIP PIK3R4 POLE2 PQBP1 PSMA1 SPDYE2 STK11 TERF1 TRAF2 TRIO TROAP TUBA1A TUBB	13 interactors: BANP BYSL DYNLT1 DYRK1A DYRK1B KRT31 KRT40 KRT8 MAPRE1 MAPRE3 TRAF2 TRIM23 TRO
Entrez ID		22919	10024
HPRD ID		04379	04849
Ensembl ID		ENSG00000101367	ENSG00000135451
Uniprot IDs		B4DM33 Q15691	F8VSF9 Q12815
PDB IDs		1PA7 1TXQ 1UEG 1VKA 1WU9 1YIB 1YIG 2HKQ 2HL3 2HL5 2QJZ 2R8U 3GJO 3TQ7
Enriched GO Terms of Interacting Partners?		Cell Cycle Process Mitotic Cell Cycle Process Cell Cycle Mitotic Cell Cycle Mitotic Nuclear Division Regulation Of Microtubule-based Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Division Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Cycle G2/M Transition Of Mitotic Cell Cycle Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Cell Cycle Microtubule Cytoskeleton Organization Microtubule-based Process Response To Stimulus Organelle Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Protein Complex Assembly Regulation Of Cytoskeleton Organization Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Microtubule Depolymerization Regulation Of Chromosome Segregation Cullin Deneddylation Cellular Localization Regulation Of Wnt Signaling Pathway Establishment Or Maintenance Of Cell Polarity Response To Radiation Protein Deneddylation Negative Regulation Of Microtubule Polymerization Or Depolymerization Cellular Component Assembly Spindle Checkpoint Positive Regulation Of Microtubule Polymerization Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Component Organization Microtubule Bundle Formation Response To Light Stimulus Cellular Protein Complex Assembly Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Positive Regulation Of Metabolic Process Regulation Of Apoptotic Process Cellular Response To Stimulus Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Positive Regulation Of Transferase Activity	Positive Regulation Of Microtubule Plus-end Binding Positive Regulation Of Protein Binding Positive Regulation Of Binding Regulation Of Protein Binding Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Binding Cell Cycle Mitotic Cell Cycle Mitotic Nuclear Division Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Cellular Response To Tumor Necrosis Factor Cell Division Developmental Process Response To Tumor Necrosis Factor Viral Process Intracellular Transport Of Viral Protein In Host Cell Negative Regulation Of Glial Cell Apoptotic Process Multicellular Organismal Development Response To Hydrostatic Pressure Protein Localization To Microtubule Mitotic Cell Cycle Process
Tagcloud ?		akap450 akap9 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant	adenocarcinomas aimed biomarkers blot capg carcinomas clu deceased differently expressed expressions ihc immunohistochemistry insufficient itgb3 localize microarray muc5b none ovarian prame prediction prognostic qpcr semiquantitative serous survivors tacc1 tumors
Tagcloud (Difference) ?		akap450 akap9 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant	adenocarcinomas aimed biomarkers blot capg carcinomas clu deceased differently expressed expressions ihc immunohistochemistry insufficient itgb3 localize microarray muc5b none ovarian prame prediction prognostic qpcr semiquantitative serous survivors tacc1 tumors
Tagcloud (Intersection) ?