UBOX5 and TRAIP

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		UBOX5	TRAIP
Gene Name		U-box domain containing 5	TRAF interacting protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Body	Nucleolus Perinuclear Region Of Cytoplasm
	Molecular Function	Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Ubiquitin-ubiquitin Ligase Activity	Ubiquitin-protein Transferase Activity Receptor Signaling Protein Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Protein Polyubiquitination	Apoptotic Process Signal Transduction Cell Proliferation Protein Ubiquitination Intracellular Signal Transduction
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: MLH1 NEDD4 TRAF6 TRAIP TRIM23 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2V1 UBE2W USP2 VCP	22 interactors: APP CYLD FLII MAPRE2 POLK RNF114 RNF4 TNFRSF1B TRAF1 TRAF2 TRIM23 TRIM41 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2H UBE2K UBE2U UBE2Z UBOX5 USP2
Entrez ID		22888	10293
HPRD ID		15605	05811
Ensembl ID		ENSG00000185019	ENSG00000183763
Uniprot IDs		O94941	Q9BWF2
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K63-linked Ubiquitination Cellular Macromolecule Catabolic Process Protein Catabolic Process Cellular Protein Metabolic Process Protein Metabolic Process Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Catabolic Process Cellular Response To Stress Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Protein Monoubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Innate Immune Response Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Innate Immune Response Positive Regulation Of Protein Ubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Stimulus ISG15-protein Conjugation Response To Stimulus Response To Stress Regulation Of Protein Ubiquitination Positive Regulation Of Protein Catabolic Process Immune Response-regulating Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Metabolic Process Cellular Response To DNA Damage Stimulus	Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Modification Process Cellular Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Pattern Recognition Receptor Signaling Pathway Protein Metabolic Process Innate Immune Response-activating Signal Transduction Catabolic Process Activation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway Proteolysis MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Protein K11-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Programmed Cell Death Cell Death Death Regulation Of Innate Immune Response Toll-like Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Apoptotic Process Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Proteolysis Cellular Metabolic Process Cellular Response To Stress Immune Response-regulating Signaling Pathway Innate Immune Response Cellular Response To Hypoxia Immune Response Cellular Response To Decreased Oxygen Levels Defense Response Positive Regulation Of Proteolysis Regulation Of Cell Cycle Cellular Response To Oxygen Levels Positive Regulation Of Immune Response Regulation Of Protein Catabolic Process Regulation Of Gene Expression
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Tagcloud (Difference) ?			anteroventral aromatization avpv bcl2 cyclic dense describing dictated estradiol fertility herein historical hypothalamus lh luteinizing males mammals nfkappab perinatal periventricular perspective proposing rodents surge testosterone tnfalpha tonic triggered update
Tagcloud (Intersection) ?