UBOX5

Gene Name		U-box domain containing 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Body
	Molecular Function	Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Ubiquitin-ubiquitin Ligase Activity
	Biological Process	Protein Polyubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		19 interactors: MLH1 NEDD4 TRAF6 TRAIP TRIM23 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2V1 UBE2W USP2 VCP
Entrez ID		22888
HPRD ID		15605
Ensembl ID		ENSG00000185019
Uniprot IDs		O94941
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K63-linked Ubiquitination Cellular Macromolecule Catabolic Process Protein Catabolic Process Cellular Protein Metabolic Process Protein Metabolic Process Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Catabolic Process Cellular Response To Stress Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Protein Monoubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Innate Immune Response Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Innate Immune Response Positive Regulation Of Protein Ubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Stimulus ISG15-protein Conjugation Response To Stimulus Response To Stress Regulation Of Protein Ubiquitination Positive Regulation Of Protein Catabolic Process Immune Response-regulating Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Metabolic Process Cellular Response To DNA Damage Stimulus
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