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NID2 and COL1A1
Number of citations of the paper that reports this interaction (PMID
9733643
)
43
Data Source:
BioGRID
(pull down)
NID2
COL1A1
Gene Name
nidogen 2 (osteonidogen)
collagen, type I, alpha 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Basement Membrane
Cell Surface
Extracellular Matrix
Extracellular Vesicular Exosome
Extracellular Region
Collagen Type I Trimer
Extracellular Space
Endoplasmic Reticulum Lumen
Golgi Apparatus
Secretory Granule
Extracellular Matrix
Molecular Function
Calcium Ion Binding
Protein Binding
Collagen Binding
Extracellular Matrix Structural Constituent
Protein Binding
Identical Protein Binding
Metal Ion Binding
Platelet-derived Growth Factor Binding
Biological Process
Cell Adhesion
Cell-matrix Adhesion
Extracellular Matrix Organization
Basement Membrane Organization
Skeletal System Development
Blood Vessel Development
Osteoblast Differentiation
Intramembranous Ossification
Endochondral Ossification
Receptor-mediated Endocytosis
Blood Coagulation
Visual Perception
Sensory Perception Of Sound
Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Cell-substrate Adhesion
Protein Transport
Extracellular Matrix Disassembly
Platelet Activation
Extracellular Matrix Organization
Collagen Fibril Organization
Positive Regulation Of Cell Migration
Collagen Catabolic Process
Response To Corticosteroid
Response To Estradiol
Collagen Biosynthetic Process
Protein Localization To Nucleus
Tooth Mineralization
Response To Drug
Response To Hydrogen Peroxide
Response To Peptide Hormone
Skin Morphogenesis
Cellular Response To Fibroblast Growth Factor Stimulus
Tooth Eruption
Positive Regulation Of Transcription, DNA-templated
Embryonic Skeletal System Development
Leukocyte Migration
Response To CAMP
Response To Hyperoxia
Face Morphogenesis
Bone Trabecula Formation
Cartilage Development Involved In Endochondral Bone Morphogenesis
Protein Heterotrimerization
Cellular Response To Amino Acid Stimulus
Cellular Response To Mechanical Stimulus
Cellular Response To Retinoic Acid
Cellular Response To Vitamin E
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Transforming Growth Factor Beta Stimulus
Positive Regulation Of Canonical Wnt Signaling Pathway
Cellular Response To Fluoride
Pathways
Laminin interactions
Platelet Adhesion to exposed collagen
Collagen formation
Collagen degradation
Anchoring fibril formation
Non-integrin membrane-ECM interactions
Degradation of the extracellular matrix
Assembly of collagen fibrils and other multimeric structures
Cell surface interactions at the vascular wall
Syndecan interactions
Crosslinking of collagen fibrils
ECM proteoglycans
GPVI-mediated activation cascade
Integrin cell surface interactions
Collagen biosynthesis and modifying enzymes
Platelet activation, signaling and aggregation
Scavenging by Class A Receptors
Drugs
Collagenase
Diseases
GWAS
Pulmonary function (
17903307
)
Breast cancer (
17903305
)
Response to taxane treatment (docetaxel) (
23006423
)
Protein-Protein Interactions
9 interactors:
COL13A1
COL1A1
COL4A1
ELN
HSPG2
KRTAP10-3
LAMC1
PRELP
SKIL
37 interactors:
ACHE
ATP13A2
BARD1
BGN
BMP1
BRCA1
CAPN1
CD36
CD44
CD93
COL7A1
DCN
DDR2
FGF7
FN1
HTRA1
IGFBP3
ITGA2
ITGA5
MAG
MATN2
MMP2
MMP9
NID1
NID2
P4HB
PAK1
PDGFA
PDGFB
PKD1
PRELP
SPARC
TGFBI
THBS1
TMPRSS6
TXN
VWF
Entrez ID
22795
1277
HPRD ID
05654
00362
Ensembl ID
ENSG00000087303
ENSG00000108821
Uniprot IDs
Q14112
P02452
PDB IDs
1Q7D
2LLP
3EJH
3GXE
Enriched GO Terms of Interacting Partners
?
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Extracellular Structure Organization
Endochondral Ossification
Anatomical Structure Morphogenesis
System Development
Collagen Catabolic Process
Collagen Metabolic Process
Endochondral Bone Morphogenesis
Multicellular Organismal Macromolecule Metabolic Process
Multicellular Organismal Development
Multicellular Organismal Metabolic Process
Anatomical Structure Development
Tissue Development
Protein Heterotrimerization
Bone Morphogenesis
Developmental Process
Skeletal System Development
Bone Development
Protein Trimerization
Cartilage Development Involved In Endochondral Bone Morphogenesis
Skeletal System Morphogenesis
Ossification
Organ Development
Catabolic Process
Striated Muscle Tissue Development
Muscle Tissue Development
Glycosaminoglycan Catabolic Process
Cellular Response To Amino Acid Stimulus
Cell Differentiation
Organ Morphogenesis
Anatomical Structure Formation Involved In Morphogenesis
Cellular Response To Fluoride
Glycosaminoglycan Biosynthetic Process
Blood Vessel Development
Vasculature Development
Response To Amino Acid
Tooth Eruption
Response To Fluoride
Protein Heterooligomerization
Skeletal Muscle Tissue Development
Skeletal Muscle Organ Development
Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Embryonic Skeletal System Development
Cellular Response To Acid Chemical
Glycosaminoglycan Metabolic Process
Retinal Blood Vessel Morphogenesis
Cellular Response To Vitamin E
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Extracellular Matrix Organization
Extracellular Structure Organization
Response To Wounding
Extracellular Matrix Disassembly
Wound Healing
Multicellular Organismal Development
Cell Adhesion
Anatomical Structure Development
Tissue Development
Platelet Degranulation
Developmental Process
System Development
Blood Coagulation
Hemostasis
Anatomical Structure Morphogenesis
Positive Regulation Of Epithelial Cell Migration
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Positive Regulation Of Cellular Component Movement
Regulation Of Cell Motility
Positive Regulation Of Locomotion
Positive Regulation Of Protein Metabolic Process
Regulation Of Locomotion
Regulation Of Cellular Amino Acid Metabolic Process
Response To Stress
Regulation Of Cellular Component Movement
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Body Fluid Levels
Regulation Of Cell Migration
Cell-substrate Adhesion
Regulation Of Epithelial Cell Migration
Regulation Of Cellular Ketone Metabolic Process
Positive Regulation Of Phosphorylation
Endodermal Cell Differentiation
Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Modification Process
Positive Regulation Of Protein Phosphorylation
Skeletal System Development
Regulation Of Cellular Protein Metabolic Process
Organ Development
Blood Vessel Morphogenesis
Regulation Of Phosphorus Metabolic Process
Platelet Activation
Organ Morphogenesis
Locomotion
Endoderm Formation
Angiogenesis
Regulation Of Protein Phosphorylation
Regulation Of Phosphorylation
Exocytosis
Tagcloud
?
archive
bcl6
cancerous
cebpb
checked
cufflinks
david
deg
degs
downloaded
exph5
fastqc
hg19
msx2
noiseq
paracancerous
ppp2r2c
read
samtools
sox4
srp009386
tophat
totally
transfa
trp53
uniquely
v1
vcftools
Tagcloud (Difference)
?
archive
bcl6
cancerous
cebpb
checked
cufflinks
david
deg
degs
downloaded
exph5
fastqc
hg19
msx2
noiseq
paracancerous
ppp2r2c
read
samtools
sox4
srp009386
tophat
totally
transfa
trp53
uniquely
v1
vcftools
Tagcloud (Intersection)
?