NID2 and ELN

Number of citations of the paper that reports this interaction (PMID 10544250)
12

Data Source:
HPRD (in vitro)

		NID2	ELN
Gene Name		nidogen 2 (osteonidogen)	elastin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Basement Membrane Cell Surface Extracellular Matrix Extracellular Vesicular Exosome	Extracellular Region Proteinaceous Extracellular Matrix Elastic Fiber
	Molecular Function	Calcium Ion Binding Protein Binding Collagen Binding	Extracellular Matrix Structural Constituent Protein Binding
	Biological Process	Cell Adhesion Cell-matrix Adhesion Extracellular Matrix Organization Basement Membrane Organization	Respiratory Gaseous Exchange Blood Circulation Cell Proliferation Organ Morphogenesis Extracellular Matrix Disassembly Extracellular Matrix Organization
Pathways		Laminin interactions	Molecules associated with elastic fibres Elastic fibre formation Degradation of the extracellular matrix
Drugs			Rofecoxib
Diseases
GWAS		Pulmonary function ( 17903307)
Protein-Protein Interactions		9 interactors: COL13A1 COL1A1 COL4A1 ELN HSPG2 KRTAP10-3 LAMC1 PRELP SKIL	21 interactors: ASS1 BGN CKMT2 CLU DCN ELANE FBLN1 FBLN2 FBN1 FBN2 FCN1 FKBP10 LGALS3 LOX LOXL1 LYZ MAGEH1 MFAP2 NID2 PRTN3 SPINK1
Entrez ID		22795	2006
HPRD ID		05654	00556
Ensembl ID		ENSG00000087303	ENSG00000049540
Uniprot IDs		Q14112	B3KRT8 B4E3S4 E7EN65 E7ENM0 G3V0G6 G5E950 P15502 Q59H17 Q6ZUN2 Q8NBI4
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Disassembly Extracellular Matrix Organization Extracellular Structure Organization Endochondral Ossification Anatomical Structure Morphogenesis System Development Collagen Catabolic Process Collagen Metabolic Process Endochondral Bone Morphogenesis Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Development Multicellular Organismal Metabolic Process Anatomical Structure Development Tissue Development Protein Heterotrimerization Bone Morphogenesis Developmental Process Skeletal System Development Bone Development Protein Trimerization Cartilage Development Involved In Endochondral Bone Morphogenesis Skeletal System Morphogenesis Ossification Organ Development Catabolic Process Striated Muscle Tissue Development Muscle Tissue Development Glycosaminoglycan Catabolic Process Cellular Response To Amino Acid Stimulus Cell Differentiation Organ Morphogenesis Anatomical Structure Formation Involved In Morphogenesis Cellular Response To Fluoride Glycosaminoglycan Biosynthetic Process Blood Vessel Development Vasculature Development Response To Amino Acid Tooth Eruption Response To Fluoride Protein Heterooligomerization Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Positive Regulation Of Cell Morphogenesis Involved In Differentiation Embryonic Skeletal System Development Cellular Response To Acid Chemical Glycosaminoglycan Metabolic Process Retinal Blood Vessel Morphogenesis Cellular Response To Vitamin E Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta	Extracellular Matrix Organization Extracellular Structure Organization Extracellular Matrix Disassembly Sequestering Of TGFbeta In Extracellular Matrix Sequestering Of Extracellular Ligand From Receptor Response To Other Organism Response To Biotic Stimulus Peptide Cross-linking Via Chondroitin 4-sulfate Glycosaminoglycan Dermatan Sulfate Biosynthetic Process Response To Bacterium Dermatan Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Metabolic Process Chondroitin Sulfate Catabolic Process Extracellular Negative Regulation Of Signal Transduction Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin Chondroitin Sulfate Biosynthetic Process Regulation Of Calcium Ion Import Chondroitin Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Interleukin-8 Production Response To External Stimulus Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Lipid Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Peptide Cross-linking Defense Response Negative Regulation Of Endocytosis Multicellular Organismal Development Argininosuccinate Metabolic Process Negative Regulation Of Immunological Synapse Formation Positive Regulation Of Tau-protein Kinase Activity Regulation Of Neuronal Signal Transduction Microglial Cell Proliferation Proteoglycan Biosynthetic Process Glycosaminoglycan Catabolic Process Chondroitin Sulfate Metabolic Process Regulation Of Nitric Oxide Biosynthetic Process System Development Response To Stress Chaperone-mediated Protein Folding Regulation Of Reactive Oxygen Species Biosynthetic Process Collagen Catabolic Process Wound Healing Immune System Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Neurofibrillary Tangle Assembly Protein Deamination Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Cellular Response To Amine Stimulus Neutrophil Mediated Killing Of Fungus
Tagcloud ?			additive amounts bioactive compound cosmetics curcuma curcumin detroit elastic elastin enhance extract fbn1 fibers fibrillin fibroblast food foods generally herbal longa medicine mum polyphenol promoters rhizome spice tropoelastin yellow
Tagcloud (Difference) ?			additive amounts bioactive compound cosmetics curcuma curcumin detroit elastic elastin enhance extract fbn1 fibers fibrillin fibroblast food foods generally herbal longa medicine mum polyphenol promoters rhizome spice tropoelastin yellow
Tagcloud (Intersection) ?