STK16 and CSKMT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STK16	CSKMT
Description		serine/threonine kinase 16	citrate synthase lysine methyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Membrane Nuclear Body Perinuclear Region Of Cytoplasm	Mitochondrion Mitochondrial Matrix
	Molecular Function	Nucleotide Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	Protein Binding Methyltransferase Activity Lysine N-methyltransferase Activity Protein-lysine N-methyltransferase Activity Transferase Activity
	Biological Process	Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus	Tricarboxylic Acid Cycle Protein Methylation Peptidyl-lysine Trimethylation Peptidyl-lysine Monomethylation Peptidyl-lysine Dimethylation Methylation
Pathways			Maturation of TCA enzymes and regulation of TCA cycle
Drugs		Fostamatinib
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		84 interacting genes: ADAMTSL4 AGR2 ARNT2 ATP23 BHLHA9 CALCOCO2 CBX3 CCDC33 CFP CRX CSKMT CSNK2B CYSRT1 DDIT4L DNAJA3 DRG1 EFEMP2 EFHC2 ELK1 FLACC1 FRS3 FXR1 GABPA IKZF3 INCA1 KCTD14 KCTD17 KLHL20 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP13-1 KRTAP13-2 KRTAP26-1 KRTAP6-3 MBP MEOX2 MGAT5B MIER3 MIIP MTUS2 NAA80 NAGK NBPF19 NIF3L1 NOTCH2NLA PCSK5 PKNOX2 PLA2G10 PLSCR1 PLSCR3 PRDM6 PRKAR1B PTH1R REL RFX6 RPIA RSPO4 SAXO1 SKIL SOCS2 SPRY2 SSC4D TCF12 TCF4 TLE5 TNFAIP1 TRAF3IP2 TRIM27 TRIM42 TRIP6 USP54 YPEL3 ZMAT1 ZNF330 ZNF343 ZNF774	6 interacting genes: BPIFA1 KRTAP11-1 KRTAP13-2 KRTAP19-6 STK16 TEKT5
Entrez ID		8576	751071
HPRD ID		05281	18960
Ensembl ID		ENSG00000115661	ENSG00000214756
Uniprot IDs		B4DPS1 B8ZZI5 O75716	A8MUP2
PDB IDs		2BUJ
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Lead Ion Binding Response To Peptide Response To Cytokine Identical Protein Binding Mercury Ion Binding PML Body	Intermediate Filament Immune Response In Nasopharyngeal-associated Lymphoid Tissue Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Keratin Filament Immune Response In Gut-associated Lymphoid Tissue Structural Molecule Activity
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