RSPH9 and TSPO2

Data Source: HiPPIP (Novel)

		RSPH9	TSPO2
Name		radial spoke head component 9	translocator protein 2
Structure			No pdb structure
GO Annotations	Cellular Component	Radial Spoke Radial Spoke Head Cytoplasm Cytoskeleton Cilium Axoneme Motile Cilium Sperm Flagellum Cell Projection Kinocilium 9+2 Motile Cilium Radial Spoke Head 1 Radial Spoke Head 3	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Organelle Membrane
	Molecular Function	Protein Binding	Protein Binding Cholesterol Binding 5-aminolevulinic Acid Transmembrane Transporter Activity
	Biological Process	Cilium Movement Cell Projection Organization Axoneme Assembly Motile Cilium Assembly Cilium Movement Involved In Cell Motility Radial Spoke Assembly Axonemal Central Apparatus Assembly	Intracellular Cholesterol Transport Lipid Droplet Organization Enucleate Erythrocyte Differentiation Import Across Plasma Membrane 5-aminolevulinic Acid Import Across Plasma Membrane
Diseases		Primary ciliary dyskinesia, including: Primary ciliary dyskinesia; Kartagener syndrome	None
GWAS		Intracranial aneurysm ( 29531279 ) Waist-to-hip ratio adjusted for BMI ( 26426971 ) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )	Gastric cancer ( 26129866 ) Non-cardia gastric cancer ( 26129866 )
Novel Interactors		9 novel interactors: ADCY10P1 DRC5 KLHDC3 LINC03040 LRRC73 OARD1 SPATS1 TAF8 TSPO2	1 novel interactors: RSPH9
Interacting Genes		2 interacting genes: HMG20A PNMA1	62 interacting genes: AHNAK2 AQP6 ARL13B ASGR2 ASZ1 BIK CD53 CD69 CD79A CERS4 CLDN4 CNR2 COL4A5 CPLX4 CREB3L1 DKK4 EBP EFNA5 EMP1 ERGIC3 ERP29 FCER1G FCGR1A FFAR2 FKBP7 FNDC9 FXYD3 GGT7 GJB5 GPR152 GPR42 GPX8 IGFBP5 KCNJ6 KLRC1 LRRC59 MAL MARCHF2 MFF MFSD6 MS4A1 PDZK1IP1 PLEKHO1 PSCA RELL2 RETREG3 RPRM SLC10A1 SLC10A6 SLC16A2 SLC18A1 SLC34A2 SLC35H1 SLC41A3 SLC7A1 SPAG4 STOM SYT2 TMEM140 TMEM54 TMEM80 VSIR
Entrez ID		221421	222642
HPRD ID		12875	16569
Ensembl ID		ENSG00000172426	ENSG00000112212
Uniprot IDs		Q9H1X1	Q5TGU0
PDB IDs		8J07	Not available
GO Terms Enriched among Interactors		DNA-templated Transcription Open Complex Formation ADP-ribosyl-[dinitrogen Reductase] Hydrolase Activity 5-aminolevulinic Acid Import Across Plasma Membrane 5-aminolevulinic Acid Transmembrane Transporter Activity	Membrane Plasma Membrane Protein Binding Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I External Side Of Plasma Membrane Positive Regulation Of Type III Hypersensitivity Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Type IIa Hypersensitivity Positive Regulation Of Acute Inflammatory Response Bile Acid:sodium Symporter Activity Transmembrane Transport Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Hypersensitivity Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Antigen Processing And Presentation Of Exogenous Peptide Antigen Sodium Ion Transport Regulation Of Acute Inflammatory Response Antigen Processing And Presentation Of Exogenous Antigen Immune Response-regulating Signaling Pathway Serotonin Transport