RSPH9 and DRC5

Data Source: HiPPIP (Novel)

		RSPH9	DRC5
Name		radial spoke head component 9	dynein regulatory complex subunit 5
Structure
GO Annotations	Cellular Component	Radial Spoke Radial Spoke Head Cytoplasm Cytoskeleton Cilium Axoneme Motile Cilium Sperm Flagellum Cell Projection Kinocilium 9+2 Motile Cilium Radial Spoke Head 1 Radial Spoke Head 3	Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Cilium Movement Cell Projection Organization Axoneme Assembly Motile Cilium Assembly Cilium Movement Involved In Cell Motility Radial Spoke Assembly Axonemal Central Apparatus Assembly	Microtubule-based Movement Flagellated Sperm Motility
Diseases		Primary ciliary dyskinesia, including: Primary ciliary dyskinesia; Kartagener syndrome	None
GWAS		Intracranial aneurysm ( 29531279 ) Waist-to-hip ratio adjusted for BMI ( 26426971 ) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )	No GWAS studies recorded
Interacting Genes		2 interacting genes: HMG20A PNMA1	None recorded
Entrez ID		221421	202500
HPRD ID		12875	14568
Ensembl ID		ENSG00000172426	ENSG00000146221
Uniprot IDs		Q9H1X1	Q5JU00
PDB IDs		8J07	8J07
GO Terms Enriched among Interactors		DNA-templated Transcription Open Complex Formation ADP-ribosyl-[dinitrogen Reductase] Hydrolase Activity 5-aminolevulinic Acid Import Across Plasma Membrane 5-aminolevulinic Acid Transmembrane Transporter Activity	DNA-templated Transcription Open Complex Formation Radial Spoke Head 1 Radial Spoke Assembly Radial Spoke Head 3 Axonemal Central Apparatus Assembly Radial Spoke Head