OLFM2 and ROBO2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		OLFM2	ROBO2
Gene Name		olfactomedin 2	roundabout, axon guidance receptor, homolog 2 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Cell Junction Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Selective Glutamate Receptor Complex Synapse	Cell Surface Integral Component Of Membrane Axolemma Extracellular Vesicular Exosome
	Molecular Function		Protein Binding Axon Guidance Receptor Activity Identical Protein Binding
	Biological Process	Protein Secretion	Metanephros Development Ureteric Bud Development Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Central Nervous System Development Brain Development Axon Midline Choice Point Recognition Olfactory Bulb Interneuron Development Retinal Ganglion Cell Axon Guidance Cellular Response To Hormone Stimulus Positive Regulation Of Axonogenesis Negative Regulation Of Negative Chemotaxis Negative Regulation Of Synapse Assembly Apoptotic Process Involved In Luteolysis
Pathways			Axon guidance Regulation of Commissural axon pathfinding by Slit and Robo Signaling by Robo receptor
Drugs
Diseases
GWAS		Menarche (age at onset) ( 21102462)	Brain imaging in schizophrenia (interaction) ( 19023125) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000)
Protein-Protein Interactions		11 interactors: BLOC1S6 EIF1 FANCF GNB5 KRTAP10-3 NBAS PKM ROBO2 RPS6 SRSF5 ST13	16 interactors: BNIP3L CENPU CPE HLA-DPB1 NR1H2 NR4A1 OLFM2 PPP1R1B RDH11 ROBO1 RPS6KA5 SLIT2 SLIT3 SSRP1 TRIM13 UBQLN4
Entrez ID		93145	6092
HPRD ID		10127	11895
Ensembl ID		ENSG00000105088	ENSG00000185008
Uniprot IDs		K7EIS8 O95897	Q9HCK4
PDB IDs			1UEM 1UJT 2EDJ
Enriched GO Terms of Interacting Partners?		Ovulation Cycle Process Negative Regulation Of Negative Chemotaxis Female Gonad Development Reproductive Structure Development Reproductive System Development Ovulation Cycle Development Of Primary Female Sexual Characteristics MRNA Metabolic Process Apoptotic Process Involved In Luteolysis Negative Regulation Of Protein Refolding Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Negative Chemotaxis Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Axon Midline Choice Point Recognition Chaperone Cofactor-dependent Protein Refolding Luteolysis Ribonucleoprotein Complex Assembly Negative Regulation Of Voltage-gated Calcium Channel Activity Oogenesis Stage Activation-induced Cell Death Of T Cells Secretion Of Lysosomal Enzymes Intracellular Transport Cytoplasmic Transport RNA Catabolic Process Axon Choice Point Recognition Developmental Process Involved In Reproduction Pigment Granule Maturation Synaptic Vesicle Docking Endosome To Melanosome Transport Multicellular Organismal Reproductive Process Olfactory Bulb Interneuron Development T Cell Proliferation Involved In Immune Response Gonad Development Translational Initiation Development Of Primary Sexual Characteristics Cellular Pigment Accumulation Multicellular Organism Reproduction Ribosomal Small Subunit Assembly Dosage Compensation By Inactivation Of X Chromosome Golgi Vesicle Transport Dosage Compensation Positive Regulation Of Pigment Cell Differentiation	Roundabout Signaling Pathway Negative Regulation Of Chemokine-mediated Signaling Pathway Negative Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Response To Cytokine Stimulus Negative Chemotaxis Cell Migration Involved In Sprouting Angiogenesis Chemorepulsion Involved In Postnatal Olfactory Bulb Interneuron Migration Regulation Of Cytokine-mediated Signaling Pathway Apoptotic Process Involved In Luteolysis Blood Vessel Endothelial Cell Migration Regulation Of Negative Chemotaxis Luteolysis Response To Cortisol Sprouting Angiogenesis Mammary Duct Terminal End Bud Growth Signal Transduction Tangential Migration From The Subventricular Zone To The Olfactory Bulb Cellular Response To Stimulus Olfactory Bulb Interneuron Development Axon Extension Involved In Axon Guidance Signaling Endothelial Cell Migration Cell Communication Chemotaxis Cerebral Cortex Tangential Migration Positive Regulation Of Cell Death Epithelial Cell Migration Epithelium Migration Olfactory Bulb Interneuron Differentiation Response To External Stimulus Axon Guidance Developmental Growth Involved In Morphogenesis Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Chemotaxis Response To Stimulus Apoptotic Process Involved In Development Ameboidal-type Cell Migration Response To Steroid Hormone Regulation Of Cellular Process Regulation Of Protein Metabolic Process Forebrain Neuron Development Substrate-dependent Cell Migration Apoptotic Process Axonogenesis Olfactory Bulb Development Axon Extension Programmed Cell Death Cell Surface Receptor Signaling Pathway Olfactory Lobe Development Cell Death
Tagcloud ?			arhgap18 circuitry connectivity ctxn3 deeper dlpfc epistatic fgf17 forebrain glypican gpc1 gsea gwas leverages networks neuroimaging perturbed postmortem qt quantifying reorganization robo1 rsrc1 slc12a2 strengths tnik trait unanticipated visualizing
Tagcloud (Difference) ?			arhgap18 circuitry connectivity ctxn3 deeper dlpfc epistatic fgf17 forebrain glypican gpc1 gsea gwas leverages networks neuroimaging perturbed postmortem qt quantifying reorganization robo1 rsrc1 slc12a2 strengths tnik trait unanticipated visualizing
Tagcloud (Intersection) ?