ERBB2 and UBB

  • Number of citations of the paper that reports this interaction (PMID 12239347)
  • 106
  • Data Source:
  • HPRD (in vivo)

ERBB2

UBB

Gene Name erb-b2 receptor tyrosine kinase 2 ubiquitin B
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 110 interactors: ABL1 ABL2 ACPP ANKS1A ANKS1B APBB1 APBB3 BCAR3 BLK BLNK BMX BTC CAV1 CBL CD82 CHN1 CISH CLNK CRK CRKL CTNNB1 DAB1 DLG4 DOK1 DOK4 DOK6 EGF EGFR ERBB2IP ERBB3 ERBB4 ERRFI1 ESR1 FER FGR GRAP2 GRB2 GRB7 HDAC6 HLA-A HSP90AA1 HSP90B1 IL6ST IRS1 IRS4 ITGA5 ITGB4 ITK JAK1 JAK2 JUP MAPK8IP1 MAPK8IP2 MATK MUC1 MUC4 NCK2 NF2 NRG1 PAK1 PICK1 PIK3C2A PIK3C2B PIK3R1 PIK3R2 PIK3R3 PLCG1 PLCG2 PTK2 PTK2B PTPN11 PTPN18 RASA1 RIN1 RIN2 SERPINA3 SH2B2 SH2B3 SH2D1B SH2D2A SH2D3A SH2D5 SH3BGRL3 SH3BP2 SHC1 SHC2 SHC3 SLA SLA2 SOCS1 SOS1 SRC SRPK1 STAT1 STAT3 STUB1 SUPT6H SYK TEC TGFA TLN1 TNS2 TNS3 TOB1 TXK UBB USP2 VAV1 VAV2 VAV3 67 interactors: APP ATXN3 BIRC2 BRCA1 CALCOCO2 CDC25A CDC34 CDKN1B CDT1 CDX2 CHEK1 DAZAP2 DUSP1 ECT2 EGFR ELF4 EPS15 ERBB2 FANCD2 FSHR HDAC6 HGS HLA-A IKBKB IKBKG JUN LIG4 LYN MAPT MDM2 MYBL2 MYC NR3C1 NTRK1 NTRK2 PARK2 PCNA PIN1 POLI PSMD4 RABGEF1 RAD23A RAD23B RNF11 SENP8 SH3KBP1 SKP2 SMAD4 SMURF1 SNCA SNCAIP SQSTM1 STUB1 SYK TGFBR1 TP53 TRAF6 TRIM37 TRIM5 UBASH3A UBASH3B UBE2N UBE3A UBQLN1 USP1 WWOX XIAP
Entrez ID 2064 7314
HPRD ID 01281 06771
Ensembl ID ENSG00000141736 ENSG00000170315
Uniprot IDs P04626 P0CG47 Q5U5U6
PDB IDs 1MFG 1MFL 1MW4 1N8Z 1OVC 1QR1 1S78 2A91 2JWA 2KS1 2L4K 3BE1 3H3B 3MZW 3N85 3PP0 3RCD 4GFU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
almost  amount  attenuation  consequently  display  downregulated  downregulation  effectively  every  hypothesized  inducible  inhibiting  kd  knockdown  oncogenic  overcome  polyubiquitin  reports  sensitization  sirna  stabilization  stress  suppressor  taken  tnfalpha  ubiquitin  ubiquitination  weakening  xenograft 
Tagcloud (Difference) ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
almost  amount  attenuation  consequently  display  downregulated  downregulation  effectively  every  hypothesized  inducible  inhibiting  kd  knockdown  oncogenic  overcome  polyubiquitin  reports  sensitization  sirna  stabilization  stress  suppressor  taken  tnfalpha  ubiquitin  ubiquitination  weakening  xenograft 
Tagcloud (Intersection) ?