ERBB2 and NRG1

  • Number of citations of the paper that reports this interaction (PMID 7592681)
  • 13

ERBB2

NRG1

Gene Name erb-b2 receptor tyrosine kinase 2 neuregulin 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 110 interactors: ABL1 ABL2 ACPP ANKS1A ANKS1B APBB1 APBB3 BCAR3 BLK BLNK BMX BTC CAV1 CBL CD82 CHN1 CISH CLNK CRK CRKL CTNNB1 DAB1 DLG4 DOK1 DOK4 DOK6 EGF EGFR ERBB2IP ERBB3 ERBB4 ERRFI1 ESR1 FER FGR GRAP2 GRB2 GRB7 HDAC6 HLA-A HSP90AA1 HSP90B1 IL6ST IRS1 IRS4 ITGA5 ITGB4 ITK JAK1 JAK2 JUP MAPK8IP1 MAPK8IP2 MATK MUC1 MUC4 NCK2 NF2 NRG1 PAK1 PICK1 PIK3C2A PIK3C2B PIK3R1 PIK3R2 PIK3R3 PLCG1 PLCG2 PTK2 PTK2B PTPN11 PTPN18 RASA1 RIN1 RIN2 SERPINA3 SH2B2 SH2B3 SH2D1B SH2D2A SH2D3A SH2D5 SH3BGRL3 SH3BP2 SHC1 SHC2 SHC3 SLA SLA2 SOCS1 SOS1 SRC SRPK1 STAT1 STAT3 STUB1 SUPT6H SYK TEC TGFA TLN1 TNS2 TNS3 TOB1 TXK UBB USP2 VAV1 VAV2 VAV3 7 interactors: ADAM19 EGF ERBB2 ERBB3 ERBB4 IKZF4 LIMK1
Entrez ID 2064 3084
HPRD ID 01281 00802
Ensembl ID ENSG00000141736 ENSG00000157168
Uniprot IDs P04626 A6MW55 A6MW56 B0FWZ3 B0FYA7 B0FYA8 B0FYA9 B7Z1D7 B7Z1E3 Q02297 Q6PK61 Q7RTW3 Q7RTW5
PDB IDs 1MFG 1MFL 1MW4 1N8Z 1OVC 1QR1 1S78 2A91 2JWA 2KS1 2L4K 3BE1 3H3B 3MZW 3N85 3PP0 3RCD 4GFU 1HAE 1HAF 1HRE 1HRF 3U7U
Enriched GO Terms of Interacting Partners?
Tagcloud ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
appreciated  cardiac  cardiomyocyte  cardiomyocytes  cardiomyopathy  chamber  conscious  contractility  dilatation  dilated  dilation  echocardiography  ecs  ejection  erbb  fractional  hearts  isoproterenol  mechanistically  neuregulin  normalization  normalized  paracrine  pecam  proper  shortening  systolic  tightly 
Tagcloud (Difference) ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
appreciated  cardiac  cardiomyocyte  cardiomyocytes  cardiomyopathy  chamber  conscious  contractility  dilatation  dilated  dilation  echocardiography  ecs  ejection  erbb  fractional  hearts  isoproterenol  mechanistically  neuregulin  normalization  normalized  paracrine  pecam  proper  shortening  systolic  tightly 
Tagcloud (Intersection) ?