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STX2 and VAMP3
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
STX2
VAMP3
Description
syntaxin 2
vesicle associated membrane protein 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Plasma Membrane
Endomembrane System
Membrane
Basolateral Plasma Membrane
Lamellipodium
SNARE Complex
Protein-containing Complex
Intracellular Membrane-bounded Organelle
Presynaptic Active Zone Membrane
Endosome
Early Endosome
Cytosol
Plasma Membrane
Cell Surface
Membrane
Transport Vesicle
Clathrin-coated Vesicle
Secretory Granule
Clathrin-coated Endocytic Vesicle Membrane
Phagocytic Vesicle Membrane
SNARE Complex
Cytoplasmic Vesicle
Early Endosome Membrane
Trans-Golgi Network Membrane
Neuron Projection
Intracellular Membrane-bounded Organelle
Synapse
Phagocytic Vesicle
Perinuclear Region Of Cytoplasm
Recycling Endosome
Recycling Endosome Membrane
Molecular Function
SNARE Binding
Structural Molecule Activity
SNAP Receptor Activity
Protein Binding
Identical Protein Binding
Calcium-dependent Protein Binding
SNAP Receptor Activity
Protein Binding
Syntaxin-1 Binding
Biological Process
Intracellular Protein Transport
Exocytosis
Signal Transduction
Acrosome Reaction
Ectoderm Development
Animal Organ Morphogenesis
Vesicle-mediated Transport
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Cellular Response To Oxidative Stress
Vesicle Docking
Cornified Envelope Assembly
Positive Regulation Of Receptor Recycling
Positive Regulation Of Immunoglobulin Production
Exocytosis
Vesicle Docking Involved In Exocytosis
Vesicle Fusion
Protein Transport
Vesicle-mediated Transport
Calcium-ion Regulated Exocytosis
Substrate Adhesion-dependent Cell Spreading
SNARE Complex Assembly
Retrograde Transport, Endosome To Golgi
Golgi To Plasma Membrane Protein Transport
Establishment Of Localization In Cell
Membrane Fusion
Protein-containing Complex Assembly
Mucus Secretion
Cellular Response To Type II Interferon
Negative Regulation Of Secretion By Cell
Regulation Of Histamine Secretion By Mast Cell
Pathways
ER-Phagosome pathway
Retrograde transport at the Trans-Golgi-Network
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
RHOA GTPase cycle
RHOB GTPase cycle
RHOC GTPase cycle
CDC42 GTPase cycle
RAC1 GTPase cycle
RAC2 GTPase cycle
RHOD GTPase cycle
RHOQ GTPase cycle
RHOH GTPase cycle
RHOG GTPase cycle
RHOJ GTPase cycle
RAC3 GTPase cycle
RHOF GTPase cycle
Drugs
Diseases
GWAS
Initial pursuit acceleration in psychotic disorders (
29064472
)
Metabolite levels (
23823483
)
Plasma plasminogen activator levels (
24578379
)
vWF levels (
30586737
)
Crohn's disease (
21102463
28067908
)
DHEAS levels (
34748635
)
Inflammatory bowel disease (
28067908
)
Morning vs. evening chronotype (
26835600
)
Periodontal microbiota (
22699663
)
Ulcerative colitis (
28067908
)
Interacting Genes
65 interacting genes:
AARD
ABI3
ANKRD46
APOL2
BET1
BLOC1S2
CD53
CDC23
CERT1
CPLX2
CTSA
CYBC1
EBAG9
ENTPD3
FGA
GET1
GIMAP5
MIP
MRPL11
MTG1
NAPB
NINJ2
PCGF2
PLN
PLPP4
RMDN3
RNF4
RTP2
SEC22A
SEC22B
SERP1
SLC18A1
SNAP25
SNAP29
SNCA
STRIT1
STX12
STX16
STX1A
STX1B
STX3
STX4
STX5
STX6
STX7
STX8
STXBP1
STXBP2
STXBP5L
SYT1
SYT4
SYT7
TMEM120A
TMEM120B
TSPAN8
UBE2I
UNC13B
VAMP2
VAMP3
VAMP5
VAPB
VTI1B
ZCCHC12
ZFPL1
ZNF785
63 interacting genes:
ACAP1
AHNAK2
AIG1
APP
AQP6
ARL13B
BCAP31
BCL2L13
BIK
BSCL2
BSND
CD79A
CIAO2A
CLDN7
CLEC14A
COMT
DDB1
DNAJC5
EBP
ELOVL4
ERGIC3
FAM174A
FAM209A
FAM210B
GORAB
GPX8
HSD17B13
IKBKG
KCNK5
LHFPL5
LMNA
MGST2
MGST3
NELFE
NEMP1
PDZK1IP1
PLEKHO1
PTGES
RETREG3
RMDN3
SAR1A
SCN3B
SLC10A1
SLC10A6
SLC16A2
SNAP23
STX16
STX1A
STX2
STX3
STX4
TM4SF19
TM4SF20
TMEM237
TMEM31
TMEM35A
TMEM52B
TMEM86B
TMPPE
TMX2
VAMP2
VEGFD
VSIR
Entrez ID
2054
9341
HPRD ID
11816
04711
Ensembl ID
ENSG00000111450
ENSG00000049245
Uniprot IDs
A0A994J5V9
A0A994J840
P32856
Q15836
Q6FGG2
PDB IDs
Enriched GO Terms of Interacting Partners
?
SNAP Receptor Activity
SNARE Complex
Organelle Localization By Membrane Tethering
SNARE Binding
Membrane Docking
Vesicle Docking
Vesicle Fusion
Organelle Membrane Fusion
Membrane Fusion
Organelle Fusion
Vesicle Organization
Membrane Organization
Organelle Localization
Syntaxin Binding
Vesicle-mediated Transport
Establishment Of Localization In Cell
Synaptic Vesicle Exocytosis
Exocytosis
Calcium-ion Regulated Exocytosis
Cellular Localization
Syntaxin-1 Binding
Secretion By Cell
Regulated Exocytosis
Vesicle Docking Involved In Exocytosis
Vesicle-mediated Transport In Synapse
Neurotransmitter Transport
Calcium Ion-regulated Exocytosis Of Neurotransmitter
Establishment Of Protein Localization
Intracellular Transport
Protein Transport
Secretion
Endomembrane System
Signal Release
SNARE Complex Assembly
Synaptic Vesicle Membrane
Membrane
Regulation Of Exocytosis
Regulation Of Secretion By Cell
Regulation Of Synaptic Vesicle Priming
Regulation Of Secretion
Positive Regulation Of Exocytosis
Intracellular Protein Transport
Vesicle
Intracellular Protein Localization
Synaptic Vesicle
Neuronal Dense Core Vesicle Exocytosis
Regulation Of Vesicle Fusion
Positive Regulation Of Synaptic Transmission
Synaptic Vesicle Priming
Positive Regulation Of Calcium Ion-dependent Exocytosis
Membrane
SNAP Receptor Activity
SNARE Complex
Vesicle Fusion
Organelle Membrane Fusion
SNARE Binding
Protein Binding
Organelle Fusion
Glutathione Peroxidase Activity
Membrane Fusion
Vesicle Docking
Exocytosis
Organelle Localization By Membrane Tethering
SNARE Complex Assembly
Secretion By Cell
Specific Granule
Vesicle Organization
Membrane Docking
Endoplasmic Reticulum Membrane
Signal Release
Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex
Positive Regulation Of Protein Localization To Cell Surface
Endomembrane System
Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex
Synaptobrevin 2-SNAP-25-syntaxin-1a Complex
Endoplasmic Reticulum
Secretion
Membrane Organization
Leukotriene-C4 Synthase Activity
Bile Acid:sodium Symporter Activity
Glutathione Transferase Activity
Positive Regulation Of Synaptic Transmission
Cornified Envelope Assembly
Cellular Oxidant Detoxification
Synaptic Vesicle Exocytosis
ATP-dependent Protein Binding
Prostanoid Metabolic Process
Establishment Of Localization In Cell
Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
Vesicle-mediated Transport In Synapse
Unsaturated Fatty Acid Metabolic Process
Regulation Of Protein Localization To Cell Surface
Icosanoid Metabolic Process
Protein Transport
Icosanoid Biosynthetic Process
Plasma Membrane
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Glutathione Binding
Cellular Detoxification
Nuclear Envelope Lumen
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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