STX2 and ENTPD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STX2	ENTPD3
Description		syntaxin 2	ectonucleoside triphosphate diphosphohydrolase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Endomembrane System Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Protein-containing Complex Intracellular Membrane-bounded Organelle Presynaptic Active Zone Membrane	Plasma Membrane Membrane
	Molecular Function	SNARE Binding Structural Molecule Activity SNAP Receptor Activity Protein Binding Identical Protein Binding Calcium-dependent Protein Binding	Nucleotide Binding Apyrase Activity GDP Phosphatase Activity Protein Binding ATP Binding Hydrolase Activity Nucleoside Diphosphate Phosphatase Activity Ribonucleoside Triphosphate Phosphatase Activity UDP Phosphatase Activity
	Biological Process	Intracellular Protein Transport Exocytosis Signal Transduction Acrosome Reaction Ectoderm Development Animal Organ Morphogenesis Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cellular Response To Oxidative Stress Vesicle Docking Cornified Envelope Assembly	Nucleoside Diphosphate Catabolic Process Nucleoside Triphosphate Catabolic Process
Pathways			Phosphate bond hydrolysis by NTPDase proteins
Drugs
Diseases
GWAS		Initial pursuit acceleration in psychotic disorders ( 29064472) Metabolite levels ( 23823483) Plasma plasminogen activator levels ( 24578379) vWF levels ( 30586737)	Eosinophil percentage of white cells ( 32888494) Neuroticism ( 29255261)
Interacting Genes		65 interacting genes: AARD ABI3 ANKRD46 APOL2 BET1 BLOC1S2 CD53 CDC23 CERT1 CPLX2 CTSA CYBC1 EBAG9 ENTPD3 FGA GET1 GIMAP5 MIP MRPL11 MTG1 NAPB NINJ2 PCGF2 PLN PLPP4 RMDN3 RNF4 RTP2 SEC22A SEC22B SERP1 SLC18A1 SNAP25 SNAP29 SNCA STRIT1 STX12 STX16 STX1A STX1B STX3 STX4 STX5 STX6 STX7 STX8 STXBP1 STXBP2 STXBP5L SYT1 SYT4 SYT7 TMEM120A TMEM120B TSPAN8 UBE2I UNC13B VAMP2 VAMP3 VAMP5 VAPB VTI1B ZCCHC12 ZFPL1 ZNF785	16 interacting genes: ARL13B CREB3L1 ERGIC3 FAM209A FNDC9 GGT6 GPA33 IFNGR2 LEUTX LHFPL5 LMNA MUC1 PTPN5 STX2 SYNE4 TMEM106A
Entrez ID		2054	956
HPRD ID		11816	16014
Ensembl ID		ENSG00000111450	ENSG00000168032
Uniprot IDs		A0A994J5V9 A0A994J840 P32856	O75355
PDB IDs
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity SNARE Complex Organelle Localization By Membrane Tethering SNARE Binding Membrane Docking Vesicle Docking Vesicle Fusion Organelle Membrane Fusion Membrane Fusion Organelle Fusion Vesicle Organization Membrane Organization Organelle Localization Syntaxin Binding Vesicle-mediated Transport Establishment Of Localization In Cell Synaptic Vesicle Exocytosis Exocytosis Calcium-ion Regulated Exocytosis Cellular Localization Syntaxin-1 Binding Secretion By Cell Regulated Exocytosis Vesicle Docking Involved In Exocytosis Vesicle-mediated Transport In Synapse Neurotransmitter Transport Calcium Ion-regulated Exocytosis Of Neurotransmitter Establishment Of Protein Localization Intracellular Transport Protein Transport Secretion Endomembrane System Signal Release SNARE Complex Assembly Synaptic Vesicle Membrane Membrane Regulation Of Exocytosis Regulation Of Secretion By Cell Regulation Of Synaptic Vesicle Priming Regulation Of Secretion Positive Regulation Of Exocytosis Intracellular Protein Transport Vesicle Intracellular Protein Localization Synaptic Vesicle Neuronal Dense Core Vesicle Exocytosis Regulation Of Vesicle Fusion Positive Regulation Of Synaptic Transmission Synaptic Vesicle Priming Positive Regulation Of Calcium Ion-dependent Exocytosis	Establishment Of Apical/basal Cell Polarity Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Membrane Polarized Epithelial Cell Differentiation Establishment Of Epithelial Cell Apical/basal Polarity Establishment Of Epithelial Cell Polarity
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