STX2 and EBAG9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STX2	EBAG9
Description		syntaxin 2	estrogen receptor binding site associated antigen 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Endomembrane System Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Protein-containing Complex Intracellular Membrane-bounded Organelle Presynaptic Active Zone Membrane	Golgi Membrane Golgi Apparatus Membrane Secretory Granule
	Molecular Function	SNARE Binding Structural Molecule Activity SNAP Receptor Activity Protein Binding Identical Protein Binding Calcium-dependent Protein Binding	Protein Binding Peptidase Activator Activity Involved In Apoptotic Process
	Biological Process	Intracellular Protein Transport Exocytosis Signal Transduction Acrosome Reaction Ectoderm Development Animal Organ Morphogenesis Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cellular Response To Oxidative Stress Vesicle Docking Cornified Envelope Assembly	Regulation Of Cell Growth T Cell Mediated Cytotoxicity Apoptotic Process Adaptive Immune Memory Response Involving T Cells And B Cells
Pathways			Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Initial pursuit acceleration in psychotic disorders ( 29064472) Metabolite levels ( 23823483) Plasma plasminogen activator levels ( 24578379) vWF levels ( 30586737)	Metabolite levels ( 23823483) Nicotine dependence and major depression (severity of comorbidity) ( 30287806)
Interacting Genes		65 interacting genes: AARD ABI3 ANKRD46 APOL2 BET1 BLOC1S2 CD53 CDC23 CERT1 CPLX2 CTSA CYBC1 EBAG9 ENTPD3 FGA GET1 GIMAP5 MIP MRPL11 MTG1 NAPB NINJ2 PCGF2 PLN PLPP4 RMDN3 RNF4 RTP2 SEC22A SEC22B SERP1 SLC18A1 SNAP25 SNAP29 SNCA STRIT1 STX12 STX16 STX1A STX1B STX3 STX4 STX5 STX6 STX7 STX8 STXBP1 STXBP2 STXBP5L SYT1 SYT4 SYT7 TMEM120A TMEM120B TSPAN8 UBE2I UNC13B VAMP2 VAMP3 VAMP5 VAPB VTI1B ZCCHC12 ZFPL1 ZNF785	30 interacting genes: ACSL5 APOL2 BNIP3 C14orf180 CFHR5 CIAO2A CLEC4G CLN6 GOLPH3 GOLPH3L MGLL NEDD4 OR10AG1 ORMDL1 PEX16 PRAF2 REEP6 SLC30A2 SLC35A1 SLC35A4 SLC35B4 SNAPIN STX1A STX2 STX3 TMEM107 TPRG1 TRAF3IP3 VAPA VAPB
Entrez ID		2054	9166
HPRD ID		11816	05775
Ensembl ID		ENSG00000111450	ENSG00000147654
Uniprot IDs		A0A994J5V9 A0A994J840 P32856	O00559
PDB IDs
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity SNARE Complex Organelle Localization By Membrane Tethering SNARE Binding Membrane Docking Vesicle Docking Vesicle Fusion Organelle Membrane Fusion Membrane Fusion Organelle Fusion Vesicle Organization Membrane Organization Organelle Localization Syntaxin Binding Vesicle-mediated Transport Establishment Of Localization In Cell Synaptic Vesicle Exocytosis Exocytosis Calcium-ion Regulated Exocytosis Cellular Localization Syntaxin-1 Binding Secretion By Cell Regulated Exocytosis Vesicle Docking Involved In Exocytosis Vesicle-mediated Transport In Synapse Neurotransmitter Transport Calcium Ion-regulated Exocytosis Of Neurotransmitter Establishment Of Protein Localization Intracellular Transport Protein Transport Secretion Endomembrane System Signal Release SNARE Complex Assembly Synaptic Vesicle Membrane Membrane Regulation Of Exocytosis Regulation Of Secretion By Cell Regulation Of Synaptic Vesicle Priming Regulation Of Secretion Positive Regulation Of Exocytosis Intracellular Protein Transport Vesicle Intracellular Protein Localization Synaptic Vesicle Neuronal Dense Core Vesicle Exocytosis Regulation Of Vesicle Fusion Positive Regulation Of Synaptic Transmission Synaptic Vesicle Priming Positive Regulation Of Calcium Ion-dependent Exocytosis	Membrane Membrane Docking Vesicle Organization Organelle Localization By Membrane Tethering Vesicle Budding From Membrane Pyrimidine Nucleotide-sugar Transmembrane Transport Endoplasmic Reticulum Membrane Nucleotide-sugar Transmembrane Transport Membrane Organization SNARE Binding Membrane Fusion FFAT Motif Binding Protein Targeting To Golgi Apparatus Golgi Membrane Golgi Vesicle Budding Cargo Adaptor Activity Cellular Localization Vesicle Fusion COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Pyrimidine Nucleotide-sugar Transmembrane Transporter Activity Organelle Membrane Fusion SNAP Receptor Activity Endoplasmic Reticulum Localization Protein Transport SNARE Complex Organelle Fusion Organophosphate Ester Transport Golgi Cisterna Organelle Localization Intracellular Protein Localization Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Intracellular Transport Host-mediated Activation Of Viral Genome Replication Organelle Organization Vesicle Fusion To Plasma Membrane Endoplasmic Reticulum Organization Host-mediated Perturbation Of Viral Genome Replication Sphingomyelin Biosynthetic Process Vesicle Docking Establishment Of Localization In Cell Host-mediated Suppression Of Viral Genome Replication Establishment Of Protein Localization Intracellular Chemical Homeostasis Intracellular Protein Transport Synaptic Vesicle Membrane Organization Carbohydrate Derivative Transport Zymogen Granule Membrane Exocytosis
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