EP300 and PIN1

Number of citations of the paper that reports this interaction (PubMedID 16227615)
60

Data Source:
BioGRID (pull down)

		EP300	PIN1
Description		EP300 lysine acetyltransferase	peptidylprolyl cis/trans isomerase, NIMA-interacting 1
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Chromosome Cytoplasm Cytosol Protein-containing Complex Protein-DNA Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Midbody Ciliary Basal Body Glutamatergic Synapse Postsynaptic Cytosol
	Molecular Function	Transcription Coregulator Binding Transcription Coactivator Binding P53 Binding DNA Binding Chromatin Binding Damaged DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Histone Acetyltransferase Activity L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Protein Binding Beta-catenin Binding Zinc Ion Binding Histone H3 Acetyltransferase Activity Histone H4 Acetyltransferase Activity Acetyltransferase Activity Transferase Activity Acyltransferase Activity Nuclear Receptor Binding Chromatin DNA Binding Histone H3K18 Acetyltransferase Activity Histone H2B Acetyltransferase Activity Histone H3K27 Acetyltransferase Activity Metal Ion Binding Tau Protein Binding Nuclear Androgen Receptor Binding NF-kappaB Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Protein-lysine-acetyltransferase Activity Protein Propionyltransferase Activity Pre-mRNA Intronic Binding STAT Family Protein Binding Peptide 2-hydroxyisobutyryltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Histone Lactyltransferase (CoA-dependent) Activity Acetylation-dependent Protein Binding Peptide Crotonyltransferase Activity Peptide Butyryltransferase Activity Histone Crotonyltransferase Activity Histone Butyryltransferase Activity DNA-binding Transcription Factor Binding Histone Reader Activity Histone H3K122 Acetyltransferase Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Cytoskeletal Motor Activity Protein Binding Beta-catenin Binding Isomerase Activity Cis-trans Isomerase Activity Mitogen-activated Protein Kinase Kinase Binding GTPase Activating Protein Binding Tau Protein Binding Phosphoserine Residue Binding Phosphothreonine Residue Binding Phosphoprotein Binding Ubiquitin Ligase Activator Activity
	Biological Process	Autophagosome Assembly Negative Regulation Of Transcription By RNA Polymerase II Response To Hypoxia Somitogenesis Thigmotaxis Behavioral Defense Response Stimulatory C-type Lectin Receptor Signaling Pathway Gluconeogenesis Glycolytic Process Regulation Of Glycolytic Process Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Protein Acetylation Internal Protein Amino Acid Acetylation Apoptotic Process Canonical NF-kappaB Signal Transduction Cell Surface Receptor Signaling Pathway Via JAK-STAT Nervous System Development Heart Development Skeletal Muscle Tissue Development Learning Or Memory Circadian Rhythm Lipid Biosynthetic Process Animal Organ Morphogenesis Regulation Of Autophagy Negative Regulation Of Autophagy Positive Regulation Of Gene Expression Regulation Of Mitochondrion Organization Positive Regulation Of Neuron Projection Development N-terminal Peptidyl-lysine Acetylation Internal Peptidyl-lysine Acetylation B Cell Differentiation Platelet Formation Lung Development Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Protein-containing Complex Assembly Protein Destabilization Cellular Response To Nutrient Levels Negative Regulation Of Protein Oligomerization Cellular Response To UV Multicellular Organism Growth Megakaryocyte Development Endodermal Cell Differentiation Swimming TORC1 Signaling TORC2 Signaling Positive Regulation Of Protein Import Into Nucleus Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Response To Estrogen Host-mediated Activation Of Viral Transcription Fat Cell Differentiation Negative Regulation Of Gluconeogenesis Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Rhythmic Process Protein Stabilization Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Canonical Wnt Signaling Pathway Face Morphogenesis Regulation Of Androgen Receptor Signaling Pathway Peptidyl-lysine Propionylation Protein Localization To Chromatin Cellular Response To L-leucine Tricarboxylic Acid Metabolic Process T-helper 17 Cell Lineage Commitment Regulation Of Tubulin Deacetylation Peptidyl-lysine Crotonylation Peptidyl-lysine Butyrylation Regulation Of Cellular Response To Heat Positive Regulation Of Protein Localization To Nucleus Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of TORC1 Signaling Positive Regulation Of TORC2 Signaling Positive Regulation Of T-helper 17 Cell Lineage Commitment	Protein Peptidyl-prolyl Isomerization Response To Hypoxia Positive Regulation Of Protein Phosphorylation Protein Targeting To Mitochondrion Regulation Of Mitotic Nuclear Division Rho Protein Signal Transduction Regulation Of Gene Expression Neuron Differentiation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Stability Regulation Of Cytokinesis Negative Regulation Of Protein Catabolic Process Positive Regulation Of Transcription By RNA Polymerase II Microtubule Polymerization Synapse Organization Protein Stabilization Negative Regulation Of SMAD Protein Signal Transduction Negative Regulation Of ERK1 And ERK2 Cascade Cellular Response To Hypoxia Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Localization To Nucleus Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Cell Motility
Pathways		Regulation of gene expression by Hypoxia-inducible Factor Polo-like kinase mediated events Pre-NOTCH Transcription and Translation Pre-NOTCH Transcription and Translation PPARA activates gene expression PPARA activates gene expression Formation of the beta-catenin:TCF transactivating complex Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells NOTCH1 Intracellular Domain Regulates Transcription NOTCH1 Intracellular Domain Regulates Transcription SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription NOTCH2 intracellular domain regulates transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production HATs acetylate histones Attenuation phase Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation SUMOylation of transcription cofactors B-WICH complex positively regulates rRNA expression Activation of anterior HOX genes in hindbrain development during early embryogenesis CD209 (DC-SIGN) signaling Metalloprotease DUBs TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest Regulation of TP53 Activity through Acetylation Regulation of TP53 Activity through Methylation PI5P Regulates TP53 Acetylation Activation of the TFAP2 (AP-2) family of transcription factors RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known RUNX3 regulates NOTCH signaling RUNX3 regulates NOTCH signaling Regulation of RUNX3 expression and activity RUNX3 regulates p14-ARF NOTCH3 Intracellular Domain Regulates Transcription NOTCH3 Intracellular Domain Regulates Transcription NOTCH4 Intracellular Domain Regulates Transcription Estrogen-dependent gene expression NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux NGF-stimulated transcription NGF-stimulated transcription TRAF3-dependent IRF activation pathway TRAF6 mediated IRF7 activation FOXO-mediated transcription of cell death genes Transcriptional regulation of granulopoiesis Transcriptional regulation of granulopoiesis Regulation of FOXO transcriptional activity by acetylation Regulation of FOXO transcriptional activity by acetylation STAT3 nuclear events downstream of ALK signaling Heme signaling SARS-CoV-1 targets host intracellular signalling and regulatory pathways Nuclear events mediated by NFE2L2 Formation of paraxial mesoderm NFE2L2 regulating inflammation associated genes NFE2L2 regulating anti-oxidant/detoxification enzymes NFE2L2 regulates pentose phosphate pathway genes NFE2L2 regulating tumorigenic genes NFE2L2 regulating MDR associated enzymes NFE2L2 regulating ER-stress associated genes Regulation of NFE2L2 gene expression Regulation of NFE2L2 gene expression Zygotic genome activation (ZGA) Evasion by RSV of host interferon responses TGFBR3 expression MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis Transcriptional and post-translational regulation of MITF-M expression and activity Transcriptional and post-translational regulation of MITF-M expression and activity Regulation of PD-L1(CD274) transcription Expression of BMAL (ARNTL), CLOCK, and NPAS2 RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression	ISG15 antiviral mechanism RHO GTPases Activate NADPH Oxidases Regulation of TP53 Activity through Phosphorylation PI5P Regulates TP53 Acetylation Negative regulators of DDX58/IFIH1 signaling
Drugs			Beta-(2-Naphthyl)-Alanine 3,6,9,12,15,18-HEXAOXAICOSANE
Diseases		Rubinstein-Taybi syndrome
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 22936669) General risk tolerance (MTAG) ( 30643258) Neuroticism ( 29255261) Red cell distribution width ( 32888494) Refractive error ( 32231278) Schizophrenia ( 25056061 28991256 29483656) Type 2 diabetes ( 30297969)	Sleep duration ( 25469926)
Interacting Genes		375 interacting genes: ABL1 ACSM5 ACTA2 AHR AKT1 ALKBH4 ALX1 APEX1 AR ARHGDIA ARNT ARSF ASCL1 ASH2L ATF4 ATF5 ATR BAG6 BCAS2 BCL3 BCL6 BMAL1 BRCA1 BRMS1 C1R CALCOCO1 CARM1 CCNB1 CCND1 CDC25A CDK2 CDT1 CDX2 CEBPA CEBPB CEBPD CFH CHD4 CITED1 CITED2 CITED4 CLOCK CNOT4 COPS2 COPS6 CREBBP CRX CTBP1 CTBP2 CTF1 CTNNB1 CXCL8 CXXC1 DAO DBP DDIT3 DDX24 DECR2 DEK DTX1 DUX4 E2F1 E2F5 EEF1A1 EGR1 EID1 EID2 ELF3 ELK1 ELL EMB EPAS1 EPO ESR1 ESR2 ETS1 ETS2 ETV1 ETV4 EZH2 FBXL5 FEN1 FHL2 FOSB FOSL1 FOSL2 FOXO3 FOXP3 GAA GABPA GABPB1 GATA4 GATA5 GATA6 GCKR GLUL GOLGA2 GPBP1 GPS2 GRB2 GRIP1 GTF2B H1-1 H1-3 H2AC20 H2AC21 H2AC4 H2AC8 H2BC21 H2BC3 H3-3A H3-4 H3C1 H3C14 H4C1 H4C14 H4C16 H4C7 H4C9 HAND2 HBP1 HDAC1 HDAC3 HDAC6 HEMGN HERC1 HIF1A HMGB1 HMGN1 HMGN2 HNF1A HNRNPU HNRNPUL1 HOXA10 HOXB1 HOXB2 HOXB3 HOXB4 HOXB6 HOXB7 HOXB9 HOXD10 HOXD4 HPS6 HSP90AA2P ILF2 ILF3 IMMT ING1 ING2 ING4 ING5 IRF1 IRF2 IRF3 IRF5 IRF7 ITIH3 JDP2 JMY JUN JUNB JUND KAT2A KAT2B KAT5 KCTD5 KDM2A KLF1 KLF13 KLF2 KLF5 KPNA2 KRT18 LEF1 MAF MAGED1 MAML1 MAP2K1 MAP3K5 MAPK1 MAPK8 MAPT MAX MCM2 MCM3 MCM3AP MCM4 MCM5 MDC1 MDM2 MDM4 MEF2A MEF2C MEF2D MGMT MITF MLXIPL MN1 MORF4L1 MPG MRE11 MSH6 MSTO1 MTOR MYB MYBL2 MYC MYOD1 N4BP2 NAP1L1 NAP1L4 NBN NCOA1 NCOA2 NCOA3 NCOA6 NEDD1 NEDD4 NEIL2 NEUROD1 NFATC1 NFATC2 NFYA NFYB NOTCH1 NOXA1 NPAS2 NPM1 NR1H4 NR1I2 NR2F2 NR3C1 NR4A1 NUP98 NUPR1 OLIG2 ORC2 PAK2 PAX6 PAX8 PAXIP1 PCK2 PCNA PDHX PELP1 PIAS1 PIAS3 PIN1 PLAGL1 PLG PLSCR1 PLSCR2 PML POLB POLD2 POLI POU3F2 PPARA PPARD PPARG PPP2R5C PRKCA PRKCB PRKCD PRKDC PRMT1 PROX1 PTMA RACK1 RAD23A RAD50 RAN RB1 RBM14 RECQL4 REL RELA RORA RPL27 RPS6KA5 RPS6KB1 RPS6KB2 RUNX1 RUNX2 RUNX3 RUVBL2 SATB1 SAV1 SELENOP SENP3 SERTAD1 SET SETD1A SIK2 SIRT1 SIRT2 SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD7 SNIP1 SNW1 SOX9 SP1 SP3 SPHK1 SPIB SREBF1 SREBF2 SRY SS18 SS18L1 STAT1 STAT2 STAT3 STAT5A STAT5B STAT6 SUB1 SUMO2 SUV39H1 TACC2 TADA3 TAF1B TAL1 TCF12 TCF3 TCF4 TCF7L2 TDG TERF2 TFAP2A TGFB1I1 TGS1 THPO TINAGL1 TNIP2 TP53 TP53BP1 TP63 TP73 TRAF2 TRERF1 TRIP4 TSG101 TWIST1 UBC UBE2D1 UBE2I UBQLN1 UBTF USF2 VPS18 WDR59 WDR82 XRCC6 YWHAZ YY1 ZBTB16 ZBTB17 ZBTB48 ZBTB49 ZBTB5 ZBTB7B ZBTB8A ZC3H12A ZEB1 ZFPM2 ZNF106 ZNF148 ZNF76 ZRANB2	272 interacting genes: ABI2 ADAMTSL4 ADARB1 AJUBA AMOT ANKRD40 AP2A1 APLP1 APP ARHGEF15 ARID5A ATCAY ATN1 ATP5F1B ATP5MJ BAG6 BARD1 BCL11A BCL2 BCL6 BCLAF1 BRCA1 BRD8 BTG2 C3orf36 CAPRIN1 CARHSP1 CASP6 CBFA2T3 CBS CBY2 CCDC184 CCDC33 CCDC6 CCDC88B CCDC90B CCNB1 CCNE1 CCNK CDC25A CDC25C CDC27 CDK1 CDK11A CDK11B CDK12 CDK2 CDK9 CDKN1B CEBPA CENPB CEP55 CEP76 CHAMP1 CHPF CNKSR1 COL11A2 CPEB1 CPNE6 CSAD CSNK2A1 CSNK2A2 CSNK2B CTNNB1 DAB1 DAB2 DDAH2 DDB1 DDX17 DDX24 DDX3X DDX5 DEAF1 DHX15 DMPK DRC12 DYNC1I1 E2F4 EFS EFTUD2 EIF3G EP300 EYA2 FAAP20 FADD FASLG FHL5 FOS FOSL1 FOXI1 FOXN1 FOXO4 FOXP2 FRS2 FUCA2 G3BP1 G3BP2 GGA2 GMEB2 GOLGA2 GOLGA6L9 GPAA1 GPHN GPR152 GRSF1 HADHA HEXIM2 HNRNPC HNRNPH1 HNRNPK HNRNPU HOMEZ HOXA1 IKZF1 IKZF3 INCENP INO80E JAKMIP2 JUN KCTD7 KIF20B KIF5A KIFC3 KLHL20 KMT2B KRT31 KRT34 KRT37 KRT38 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-9 LCN2 LEPR LRIF1 MAP1S MAP3K11 MAPT MCL1 MDFI MED1 MEOX1 MEOX2 MLLT6 MOCS1 MTFR1 MTUS2 MYF5 MYT1 NAB2 NCKIPSD NCOA3 NCOR2 NEK2 NEK6 NELFA NEUROD4 NFATC2 NHERF1 NONO NR4A3 NUP35 NUP62 PABPC1 PAX6 PBX1 PDLIM7 PKIB PKM PKMYT1 PLAGL2 PLEKHG2 PLK1 PML PNMA1 POLR2A PPP1R2 PRPF8 PRRC1 PTOV1 PTPN1 QARS1 RAB4A RAF1 RAI1 RARA RBBP8 RBBP8NL RBPMS RELA REPS1 RNF208 RNPS1 RPL4 RPS6KB1 RUNX2 SCAI SCYL1 SELENOV SEPTIN9 SFPQ SGK1 SHKBP1 SMAD3 SNCAIP SNRNP200 SOCS3 SREK1 SRRM1 SRRM2 SRSF11 SSBP2 SSBP3 SSBP4 SSC5D STIL STK3 SUPT5H TAB3 TBC1D4 TCF12 TCF4 TFG TFPT THAP7 THRAP3 TLE3 TNS2 TOP2A TOX3 TP53 TP63 TP73 TRAF1 TRAF2 TRIM27 TRIM59 TRIP6 TRMT2A TSC2 TSC22D4 TUT1 U2AF2 UBB UBQLN2 UBQLN4 UBXN2B UNC119 VIRMA WEE1 WIZ WRNIP1 XRCC6 ZBTB14 ZBTB2 ZBTB22 ZBTB42 ZBTB7B ZBTB9 ZCCHC10 ZMIZ2 ZNF446 ZNF449 ZNF526 ZNF768 ZNF783
Entrez ID		2033	5300
HPRD ID		04078	03031
Ensembl ID		ENSG00000100393	ENSG00000127445
Uniprot IDs		A0A669KB12 Q09472 Q7Z6C1	Q13526
PDB IDs		1L3E 1P4Q 2K8F 2MH0 2MZD 3BIY 3I3J 3IO2 3P57 3T92 4BHW 4PZR 4PZS 4PZT 5BT3 5KJ2 5LKT 5LKU 5LKX 5LKZ 5LPK 5LPM 5NU5 5XZC 6DS6 6FGN 6FGS 6GYR 6GYT 6K4N 6PF1 6PGU 6V8B 6V8K 6V8N 6V90 7LJE 7QGS 7SS8 7SSK 7SZQ 7UGI 7VHY 7VHZ 7VI0 7W9V 7XEZ 7XFG 8E1D 8FVF 8GZC 8HAG 8HAH 8HAI 8HAJ 8HAK 9JEJ 9JUT	1F8A 1I6C 1I8G 1I8H 1NMV 1NMW 1PIN 1ZCN 2F21 2ITK 2KBU 2KCF 2LB3 2M8I 2M8J 2M9E 2M9F 2M9I 2M9J 2N1O 2Q5A 2RUC 2RUD 2RUQ 2RUR 2XP3 2XP4 2XP5 2XP6 2XP7 2XP8 2XP9 2XPA 2XPB 2ZQS 2ZQT 2ZQU 2ZQV 2ZR4 2ZR5 2ZR6 3I6C 3IK8 3IKD 3IKG 3JYJ 3KAB 3KAC 3KAD 3KAF 3KAG 3KAH 3KAI 3KCE 3NTP 3ODK 3OOB 3TC5 3TCZ 3TDB 3WH0 4GWT 4GWV 4QIB 4TNS 4TYO 4U84 4U85 4U86 5B3W 5B3X 5B3Y 5B3Z 5BMY 5GPH 5UY9 5VTI 5VTJ 5VTK 6DUN 6O33 6O34 6SVC 6SVE 6SVH 6VAJ 7AOG 7AXN 7AYF 7AZ1 7AZ2 7BDP 7BDT 7BDY 7BFW 7BG3 7BGQ 7BGR 7BGV 7BGW 7EFJ 7EFX 7EKV 7F0M 7NIF 7NIG 7NJ6 7NJ8 7NJA 7NRK 7NRL 7OQ9 7OQA 7SA5 7SUQ 7SUR 8C2G 8C3C 8SG2 8VJD 8VJE 8VJF 8VJG 9INR 9IT1
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Nucleoplasm Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Positive Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Transcription Cis-regulatory Region Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding Regulation Of Developmental Process Transcription Regulator Complex Regulation Of Cell Differentiation Positive Regulation Of Developmental Process DNA-binding Transcription Factor Binding Chromatin Binding RNA Polymerase II Transcription Regulator Complex Chromatin Organization Cellular Response To Stress Regulation Of Cell Population Proliferation RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Regulation Of Primary Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Metabolic Process Nucleoplasm Identical Protein Binding Protein Binding Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Negative Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process DNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Regulation Of Mitotic Cell Cycle Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cytosol Positive Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Nucleic Acid Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Apoptotic Signaling Pathway Chromatin Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Transcription Regulator Complex Regulation Of Cell Cycle Process Negative Regulation Of Biosynthetic Process Cell Death Apoptotic Process RNA Metabolic Process Programmed Cell Death Promoter-specific Chromatin Binding MRNA Metabolic Process Transcription Cis-regulatory Region Binding Nuclear Speck
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