EP300 and CEBPA

Number of citations of the paper that reports this interaction (PubMedID 34189442)
73

Data Source:
BioGRID (proximity labelling technology, unspecified method)
HPRD (in vitro)

		EP300	CEBPA
Description		EP300 lysine acetyltransferase	CCAAT enhancer binding protein alpha
Image
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Chromosome Cytoplasm Cytosol Protein-containing Complex Protein-DNA Complex	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Nuclear Matrix Protein-containing Complex Rb-E2F Complex CHOP-C/EBP Complex RNA Polymerase II Transcription Regulator Complex C/EBP Complex
	Molecular Function	Transcription Coregulator Binding Transcription Coactivator Binding P53 Binding DNA Binding Chromatin Binding Damaged DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Histone Acetyltransferase Activity L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Protein Binding Beta-catenin Binding Zinc Ion Binding Histone H3 Acetyltransferase Activity Histone H4 Acetyltransferase Activity Acetyltransferase Activity Transferase Activity Acyltransferase Activity Nuclear Receptor Binding Chromatin DNA Binding Histone H3K18 Acetyltransferase Activity Histone H2B Acetyltransferase Activity Histone H3K27 Acetyltransferase Activity Metal Ion Binding Tau Protein Binding Nuclear Androgen Receptor Binding NF-kappaB Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Protein-lysine-acetyltransferase Activity Protein Propionyltransferase Activity Pre-mRNA Intronic Binding STAT Family Protein Binding Peptide 2-hydroxyisobutyryltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Histone Lactyltransferase (CoA-dependent) Activity Acetylation-dependent Protein Binding Peptide Crotonyltransferase Activity Peptide Butyryltransferase Activity Histone Crotonyltransferase Activity Histone Butyryltransferase Activity DNA-binding Transcription Factor Binding Histone Reader Activity Histone H3K122 Acetyltransferase Activity	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Kinase Binding Protein Domain Specific Binding Chromatin DNA Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Sequence-specific DNA Binding Protein-containing Complex Binding Protein Heterodimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding HMG Box Domain Binding STAT Family Protein Binding DNA-binding Transcription Factor Binding
	Biological Process	Autophagosome Assembly Negative Regulation Of Transcription By RNA Polymerase II Response To Hypoxia Somitogenesis Thigmotaxis Behavioral Defense Response Stimulatory C-type Lectin Receptor Signaling Pathway Gluconeogenesis Glycolytic Process Regulation Of Glycolytic Process Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Protein Acetylation Internal Protein Amino Acid Acetylation Apoptotic Process Canonical NF-kappaB Signal Transduction Cell Surface Receptor Signaling Pathway Via JAK-STAT Nervous System Development Heart Development Skeletal Muscle Tissue Development Learning Or Memory Circadian Rhythm Lipid Biosynthetic Process Animal Organ Morphogenesis Regulation Of Autophagy Negative Regulation Of Autophagy Positive Regulation Of Gene Expression Regulation Of Mitochondrion Organization Positive Regulation Of Neuron Projection Development N-terminal Peptidyl-lysine Acetylation Internal Peptidyl-lysine Acetylation B Cell Differentiation Platelet Formation Lung Development Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Protein-containing Complex Assembly Protein Destabilization Cellular Response To Nutrient Levels Negative Regulation Of Protein Oligomerization Cellular Response To UV Multicellular Organism Growth Megakaryocyte Development Endodermal Cell Differentiation Swimming TORC1 Signaling TORC2 Signaling Positive Regulation Of Protein Import Into Nucleus Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Response To Estrogen Host-mediated Activation Of Viral Transcription Fat Cell Differentiation Negative Regulation Of Gluconeogenesis Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Rhythmic Process Protein Stabilization Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Canonical Wnt Signaling Pathway Face Morphogenesis Regulation Of Androgen Receptor Signaling Pathway Peptidyl-lysine Propionylation Protein Localization To Chromatin Cellular Response To L-leucine Tricarboxylic Acid Metabolic Process T-helper 17 Cell Lineage Commitment Regulation Of Tubulin Deacetylation Peptidyl-lysine Crotonylation Peptidyl-lysine Butyrylation Regulation Of Cellular Response To Heat Positive Regulation Of Protein Localization To Nucleus Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of TORC1 Signaling Positive Regulation Of TORC2 Signaling Positive Regulation Of T-helper 17 Cell Lineage Commitment	Urea Cycle Negative Regulation Of Transcription By RNA Polymerase II Liver Development Embryonic Placenta Development Epithelial Cell Maturation Osteoblast Development Generation Of Precursor Metabolites And Energy DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase I Acute-phase Response Mitochondrion Organization Notch Signaling Pathway Response To Nutrient Memory Cholesterol Metabolic Process Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Cytokine-mediated Signaling Pathway Myeloid Cell Differentiation Cell Differentiation Macrophage Differentiation Lung Development Granulocyte Differentiation Animal Organ Regeneration Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Vitamin B2 Regulation Of Cell Population Proliferation Glucose Homeostasis Positive Regulation Of Macrophage Activation Fat Cell Differentiation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Cell Cycle Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Inner Ear Development Positive Regulation Of Inflammatory Response White Fat Cell Differentiation Brown Fat Cell Differentiation Regulation Of Cell Cycle Lipid Homeostasis Interleukin-6-mediated Signaling Pathway White Fat Cell Proliferation Cellular Response To Lithium Ion Cellular Response To Tumor Necrosis Factor Hematopoietic Stem Cell Proliferation Cellular Response To Xenobiotic Stimulus Response To Dexamethasone Response To Phenylpropanoid Energy Homeostasis Integrated Stress Response Signaling Negative Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of DNA-templated Transcription Initiation
Pathways		Regulation of gene expression by Hypoxia-inducible Factor Polo-like kinase mediated events Pre-NOTCH Transcription and Translation Pre-NOTCH Transcription and Translation PPARA activates gene expression PPARA activates gene expression Formation of the beta-catenin:TCF transactivating complex Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells NOTCH1 Intracellular Domain Regulates Transcription NOTCH1 Intracellular Domain Regulates Transcription SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription NOTCH2 intracellular domain regulates transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production HATs acetylate histones Attenuation phase Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation SUMOylation of transcription cofactors B-WICH complex positively regulates rRNA expression Activation of anterior HOX genes in hindbrain development during early embryogenesis CD209 (DC-SIGN) signaling Metalloprotease DUBs TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest Regulation of TP53 Activity through Acetylation Regulation of TP53 Activity through Methylation PI5P Regulates TP53 Acetylation Activation of the TFAP2 (AP-2) family of transcription factors RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known RUNX3 regulates NOTCH signaling RUNX3 regulates NOTCH signaling Regulation of RUNX3 expression and activity RUNX3 regulates p14-ARF NOTCH3 Intracellular Domain Regulates Transcription NOTCH3 Intracellular Domain Regulates Transcription NOTCH4 Intracellular Domain Regulates Transcription Estrogen-dependent gene expression NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux NGF-stimulated transcription NGF-stimulated transcription TRAF3-dependent IRF activation pathway TRAF6 mediated IRF7 activation FOXO-mediated transcription of cell death genes Transcriptional regulation of granulopoiesis Transcriptional regulation of granulopoiesis Regulation of FOXO transcriptional activity by acetylation Regulation of FOXO transcriptional activity by acetylation STAT3 nuclear events downstream of ALK signaling Heme signaling SARS-CoV-1 targets host intracellular signalling and regulatory pathways Nuclear events mediated by NFE2L2 Formation of paraxial mesoderm NFE2L2 regulating inflammation associated genes NFE2L2 regulating anti-oxidant/detoxification enzymes NFE2L2 regulates pentose phosphate pathway genes NFE2L2 regulating tumorigenic genes NFE2L2 regulating MDR associated enzymes NFE2L2 regulating ER-stress associated genes Regulation of NFE2L2 gene expression Regulation of NFE2L2 gene expression Zygotic genome activation (ZGA) Evasion by RSV of host interferon responses TGFBR3 expression MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis Transcriptional and post-translational regulation of MITF-M expression and activity Transcriptional and post-translational regulation of MITF-M expression and activity Regulation of PD-L1(CD274) transcription Expression of BMAL (ARNTL), CLOCK, and NPAS2 RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression	Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of granulopoiesis Transcriptional regulation of granulopoiesis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases		Rubinstein-Taybi syndrome	Acute myeloid leukemia (AML)
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 22936669) General risk tolerance (MTAG) ( 30643258) Neuroticism ( 29255261) Red cell distribution width ( 32888494) Refractive error ( 32231278) Schizophrenia ( 25056061 28991256 29483656) Type 2 diabetes ( 30297969)	A body shape index ( 34021172) Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Apolipoprotein A1 levels ( 32203549) Asthma ( 34103634 31959851 30929738) Asthma (adult onset) ( 31036433 30929738) Asthma (childhood onset) ( 31036433 30929738) Basophil count ( 28031487) Birth weight ( 31043758) Hip index ( 34021172) Mastocytosis (KIT D816V positive) ( 33421400) Red blood cell count ( 29403010) Visceral adipose tissue volume ( 34128465) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500 25673412) White blood cell count (basophil) ( 29403010 28158719)
Interacting Genes		375 interacting genes: ABL1 ACSM5 ACTA2 AHR AKT1 ALKBH4 ALX1 APEX1 AR ARHGDIA ARNT ARSF ASCL1 ASH2L ATF4 ATF5 ATR BAG6 BCAS2 BCL3 BCL6 BMAL1 BRCA1 BRMS1 C1R CALCOCO1 CARM1 CCNB1 CCND1 CDC25A CDK2 CDT1 CDX2 CEBPA CEBPB CEBPD CFH CHD4 CITED1 CITED2 CITED4 CLOCK CNOT4 COPS2 COPS6 CREBBP CRX CTBP1 CTBP2 CTF1 CTNNB1 CXCL8 CXXC1 DAO DBP DDIT3 DDX24 DECR2 DEK DTX1 DUX4 E2F1 E2F5 EEF1A1 EGR1 EID1 EID2 ELF3 ELK1 ELL EMB EPAS1 EPO ESR1 ESR2 ETS1 ETS2 ETV1 ETV4 EZH2 FBXL5 FEN1 FHL2 FOSB FOSL1 FOSL2 FOXO3 FOXP3 GAA GABPA GABPB1 GATA4 GATA5 GATA6 GCKR GLUL GOLGA2 GPBP1 GPS2 GRB2 GRIP1 GTF2B H1-1 H1-3 H2AC20 H2AC21 H2AC4 H2AC8 H2BC21 H2BC3 H3-3A H3-4 H3C1 H3C14 H4C1 H4C14 H4C16 H4C7 H4C9 HAND2 HBP1 HDAC1 HDAC3 HDAC6 HEMGN HERC1 HIF1A HMGB1 HMGN1 HMGN2 HNF1A HNRNPU HNRNPUL1 HOXA10 HOXB1 HOXB2 HOXB3 HOXB4 HOXB6 HOXB7 HOXB9 HOXD10 HOXD4 HPS6 HSP90AA2P ILF2 ILF3 IMMT ING1 ING2 ING4 ING5 IRF1 IRF2 IRF3 IRF5 IRF7 ITIH3 JDP2 JMY JUN JUNB JUND KAT2A KAT2B KAT5 KCTD5 KDM2A KLF1 KLF13 KLF2 KLF5 KPNA2 KRT18 LEF1 MAF MAGED1 MAML1 MAP2K1 MAP3K5 MAPK1 MAPK8 MAPT MAX MCM2 MCM3 MCM3AP MCM4 MCM5 MDC1 MDM2 MDM4 MEF2A MEF2C MEF2D MGMT MITF MLXIPL MN1 MORF4L1 MPG MRE11 MSH6 MSTO1 MTOR MYB MYBL2 MYC MYOD1 N4BP2 NAP1L1 NAP1L4 NBN NCOA1 NCOA2 NCOA3 NCOA6 NEDD1 NEDD4 NEIL2 NEUROD1 NFATC1 NFATC2 NFYA NFYB NOTCH1 NOXA1 NPAS2 NPM1 NR1H4 NR1I2 NR2F2 NR3C1 NR4A1 NUP98 NUPR1 OLIG2 ORC2 PAK2 PAX6 PAX8 PAXIP1 PCK2 PCNA PDHX PELP1 PIAS1 PIAS3 PIN1 PLAGL1 PLG PLSCR1 PLSCR2 PML POLB POLD2 POLI POU3F2 PPARA PPARD PPARG PPP2R5C PRKCA PRKCB PRKCD PRKDC PRMT1 PROX1 PTMA RACK1 RAD23A RAD50 RAN RB1 RBM14 RECQL4 REL RELA RORA RPL27 RPS6KA5 RPS6KB1 RPS6KB2 RUNX1 RUNX2 RUNX3 RUVBL2 SATB1 SAV1 SELENOP SENP3 SERTAD1 SET SETD1A SIK2 SIRT1 SIRT2 SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD7 SNIP1 SNW1 SOX9 SP1 SP3 SPHK1 SPIB SREBF1 SREBF2 SRY SS18 SS18L1 STAT1 STAT2 STAT3 STAT5A STAT5B STAT6 SUB1 SUMO2 SUV39H1 TACC2 TADA3 TAF1B TAL1 TCF12 TCF3 TCF4 TCF7L2 TDG TERF2 TFAP2A TGFB1I1 TGS1 THPO TINAGL1 TNIP2 TP53 TP53BP1 TP63 TP73 TRAF2 TRERF1 TRIP4 TSG101 TWIST1 UBC UBE2D1 UBE2I UBQLN1 UBTF USF2 VPS18 WDR59 WDR82 XRCC6 YWHAZ YY1 ZBTB16 ZBTB17 ZBTB48 ZBTB49 ZBTB5 ZBTB7B ZBTB8A ZC3H12A ZEB1 ZFPM2 ZNF106 ZNF148 ZNF76 ZRANB2	831 interacting genes: AARS1 ABCE1 ABCF1 ACLY ACSL1 ACTG1 ACTN1 ACTN4 ACTR1A ACTR2 ADAR AHCY AHSA1 AIMP2 AIP AK6 ALDOA ALKBH5 ALYREF ANAPC7 ANLN ANXA5 ANXA6 AP1B1 AP2B1 AP2M1 APEH APEX1 AR ARHGAP15 ARHGDIA ARHGDIB ARHGEF2 ARL6IP4 ARPC1B ARPC3 ASNS ATF2 ATF4 ATF5 ATIC ATP1A1 ATP2A2 ATXN2 ATXN2L AURKA BAG1 BAG6 BANF1 BATF BATF2 BATF3 BCAP31 BCAT1 BCL2L2 BCLAF1 BIN2 BLMH BTF3 BTF3L4 BUB3 BUD23 BUD31 BZW1 BZW2 C11orf58 C19orf53 C1QBP C2orf49 CAB39 CACYBP CAD CALU CAMK2G CAND1 CAP1 CAPG CAPRIN1 CAPZA1 CAPZB CC2D1A CCAR2 CCDC12 CCDC7 CCNB1 CCT2 CCT3 CCT4 CCT5 CCT6A CCT7 CCT8 CCZ1 CDC42 CDK1 CDK13 CDK2 CDK4 CDK7 CDK8 CDK9 CDKN1A CDKN2AIP CDKN3 CDX1 CEBPB CEBPD CEBPE CEBPG CELF1 CELF2 CEP170 CGGBP1 CHD4 CHD8 CHEK1 CHMP4B CHMP5 CHTOP CIAPIN1 CIRBP CIT CKAP5 CLASP1 CLIC1 CLINT1 CLTA CLTB CLTC CMSS1 CNOT1 COPS3 COPS4 COPS5 CORO1A CORO1C CPNE1 CPSF6 CPSF7 CREBBP CRIPT CSDE1 CSNK1A1 CSNK2A1 CSNK2A2 CSTF3 CTNNB1 CTPS1 CUL1 CUL3 CUTA CZIB DARS1 DAZAP1 DBP DCD DCPS DCXR DDX1 DDX17 DDX19B DDX23 DDX39A DDX3X DDX41 DDX49 DDX5 DDX55 DDX6 DEK DHX15 DIDO1 DIMT1 DNAJB1 DNAJC8 DNAJC9 DNM2 DNMT1 DOCK2 DOCK8 DPP3 DRG1 DTYMK DYNC1H1 DYNC1LI1 DYNLRB1 ECPAS EDC4 EDF1 EEF1A1 EEF1B2 EEF1D EEF1E1 EEF1G EEF2 EEFSEC EIF1 EIF2A EIF2S1 EIF2S2 EIF2S3 EIF4A1 EIF4A3 EIF4B EIF4E EIF4G2 EIF4H EIF5 EIF5B ELAVL1 ELMO1 ELOB ELOC EMG1 ENY2 EP300 EP400 EPRS1 ERGIC3 ERP29 ESR1 ETF1 ETV6 EVL EWSR1 EXOSC10 EZR FAM120A FAM136A FAM32A FAM76B FAM98B FANCI FARSB FASN FDPS FEN1 FIP1L1 FKBP3 FKBP4 FKBP5 FLNA FLYWCH2 FNBP1 FOS FOSL1 FOXK1 FRG1 FUBP1 FUBP3 FUS G3BP1 G3BP2 GABARAPL2 GABPA GABPB1 GAPDH GARS1 GATA2 GATAD2A GBE1 GDI2 GET4 GLO1 GLRX3 GLTP GMFG GMNN GMPS GOPC GRB2 GRWD1 GSK3B GSN GSPT1 GSTP1 GTF2F1 GTF2F2 GTF2I GTPBP1 GTSF1 H1-2 H1-5 H2AC20 H2BC15 H3-3A H4C1 HADHA HADHB HAT1 HCFC1 HDAC1 HDAC2 HDGF HDLBP HEATR3 HEBP2 HELLS HEXIM1 HLTF HMGA1 HMGB1 HMGB2 HMGB3 HMGCS1 HMGN1 HMGN2 HMGN4 HMMR HNF1A HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPAB HNRNPD HNRNPDL HNRNPK HNRNPL HNRNPLL HNRNPR HNRNPU HNRNPUL1 HOMER3 HPCAL1 HPRT1 HSD17B4 HSPA1B HSPA4 HSPH1 HYOU1 IARS1 IFI16 IGF2BP1 IGF2BP2 IGF2BP3 IK ILF2 ILF3 ILK IMPDH2 INPP5D INTS12 IPO11 IPO7 IQGAP1 IRF2BP1 IRF2BP2 ITPA KARS1 KAT2A KAT8 KCNAB2 KHDRBS1 KHSRP KIF11 KIF2A KIF2C KIF4A KIF5B KIFC1 KNTC1 KPNB1 LARP1 LARS1 LASP1 LCP1 LDHA LDHB LIG1 LIMD2 LMAN1 LRWD1 LSM12 LSM14A LSM14B LSM2 LSM5 LSM6 LSM7 MAGOHB MAP2K7 MAP4 MAP7D1 MAPK1 MAPK8 MARS1 MAT2A MAT2B MBNL1 MCM4 MCM5 MCM7 MCTS1 MED1 MED10 MED12 MED14 MED15 MED16 MED17 MED21 MED22 MED23 MED24 MED27 MED28 MED29 MED4 MED6 MED8 METAP2 MIF MITD1 MKI67 MLKL MNDA MORC2 MORF4L1 MPO MRE11 MRTO4 MSH2 MSH6 MSN MSX2 MTA2 MTHFD1 MTPN MTREX MVK MYC MYCBP2 MYL6 MZT2B NAA10 NAA15 NAA50 NAE1 NARS1 NCAPD3 NCAPG2 NCF1 NCOA6 NEDD1 NEK6 NELFA NELFB NELFE NFYA NHERF1 NIFK NME2 NOC4L NOLC1 NONO NOP14 NOP2 NOP58 NOSIP NPEPPS NR3C1 NSFL1C NSUN2 NSUN5 NTPCR NUCKS1 NUDC NUDT16L1 NUDT21 NUP153 NUP50 NUP93 NUSAP1 NUTF2 NXF1 OLA1 ORC3 ORC5 ORC6 OTUB1 PA2G4 PABPC1 PABPC4 PAF1 PAICS PAK2 PARP1 PCBP2 PCLAF PCM1 PCMT1 PCNP PDAP1 PDCD5 PDCD6 PDIA3 PDIA4 PDS5A PDS5B PEBP1 PES1 PFDN1 PFDN2 PFDN5 PFDN6 PFKL PFKM PGAM1 PGK1 PHF6 PHGDH PIAS1 PIN1 PIN4 PKM PLIN3 PLK1 PLRG1 PNP POLDIP3 POLR1D PPA1 PPAT PPIB PPIH PPIL2 PPME1 PPP2CA PPP3CA PPP4R2 PPP4R3A PPP5C PQBP1 PRAM1 PRC1 PRDX1 PRKDC PRKRIP1 PRMT1 PRPF19 PRPF3 PRPF31 PRPF38B PRPF39 PRPF4 PRPF6 PRPS1 PRRC2A PRRC2C PSIP1 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB7 PSMC1 PSMC3 PSMC4 PSMC6 PSMD10 PSMD11 PSMD12 PSMD14 PSMD6 PSMD7 PSME1 PSME2 PSME3 PSMG1 PSPC1 PTBP1 PUF60 PUM3 PURB PYGL QKI RAB10 RAB2A RAB3GAP2 RAC1 RAD23A RAD23B RAD50 RAE1 RANBP1 RANBP2 RARA RARB RARS1 RASGRF1 RASGRP2 RAVER1 RB1 RBL1 RBM14 RBM15 RBM17 RBM22 RBM26 RBM27 RBM28 RBM3 RBM33 RBM39 RBMX RCC1 RCC2 RCOR1 RECQL RFC1 RFC2 RFC3 RFC4 RFC5 RHOA RHOG RNGTT RNH1 RPA1 RPA2 RPL9 RPP30 RPS28 RPS29 RRM1 RSL1D1 RTCB RTRAF RUNX1 RUVBL2 S100A11 S100P SAE1 SAFB SAFB2 SAR1A SARNP SART1 SBDS SCAF4 SCP2 SEH1L SEPTIN14 SEPTIN2 SEPTIN6 SEPTIN9 SERF2 SF1 SF3A1 SF3A2 SF3B6 SFPQ SIN3A SKP2 SLAIN2 SLBP SLC25A5 SLC3A2 SLFN11 SMAD3 SMAD4 SMARCA2 SMARCA4 SMARCC2 SMARCD2 SMARCE1 SMC1A SMC2 SMC3 SMC4 SMCHD1 SMNDC1 SMS SMU1 SND1 SNRNP200 SNRNP40 SNRNP70 SNRPA SNRPA1 SNRPB2 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNW1 SNX9 SORD SOX10 SOX8 SPAST SPI1 SPR SRA1 SRM SRP14 SRP19 SRP54 SRP68 SRP72 SRP9 SRRM2 SRSF7 SSB SSBP1 SSRP1 STAT1 STAU1 STEEP1 STK10 STMN1 STRAP SUB1 SUGP1 SUGP2 SUGT1 SUMO1 SUMO2 SUMO3 SURF4 SYK SYNCRIP TADA3 TALDO1 TAOK3 TARS1 TBCA TBL1XR1 TCEA1 TCERG1 TCP1 TEX30 THAP11 THOC2 THRAP3 THYN1 TIAL1 TIPRL TKT TLN1 TM9SF3 TMA16 TMA7 TMED10 TMPO TNPO2 TNPO3 TOGARAM2 TOMM34 TOP1 TOP2A TOP2B TP53 TP53BP1 TPI1 TPP2 TPT1 TPX2 TRIB2 TRIM25 TRIM33 TRIM4 TRIR TRRAP TSN TSNAX TTC9C TTF2 TTLL12 TUBB4A TUBB4B TUBG1 TUBGCP2 TUBGCP3 TWF2 TXLNA TXLNG TXN TXNDC5 TXNL1 TXNRD1 U2SURP UBA1 UBA2 UBE2I UBE2K UBQLN1 UBR5 UBTF UBXN1 UCHL3 UNG UPF1 UPF3B USP14 USP22 USP39 VARS1 VASP WARS1 WBP11 WDR74 WDR82 WIPF1 WRNIP1 XPO1 XPO5 XPOT XRCC5 XRCC6 XRN2 YBX1 YY1 ZBTB16 ZC3H11A ZC3H15 ZFR ZMAT2 ZNF207 ZRANB2 ZW10 ZYX
Entrez ID		2033	1050
HPRD ID		04078	00296
Ensembl ID		ENSG00000100393	ENSG00000245848
Uniprot IDs		A0A669KB12 Q09472 Q7Z6C1	P49715
PDB IDs		1L3E 1P4Q 2K8F 2MH0 2MZD 3BIY 3I3J 3IO2 3P57 3T92 4BHW 4PZR 4PZS 4PZT 5BT3 5KJ2 5LKT 5LKU 5LKX 5LKZ 5LPK 5LPM 5NU5 5XZC 6DS6 6FGN 6FGS 6GYR 6GYT 6K4N 6PF1 6PGU 6V8B 6V8K 6V8N 6V90 7LJE 7QGS 7SS8 7SSK 7SZQ 7UGI 7VHY 7VHZ 7VI0 7W9V 7XEZ 7XFG 8E1D 8FVF 8GZC 8HAG 8HAH 8HAI 8HAJ 8HAK 9JEJ 9JUT	6DC0 8K8C
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Nucleoplasm Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Positive Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Transcription Cis-regulatory Region Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding Regulation Of Developmental Process Transcription Regulator Complex Regulation Of Cell Differentiation Positive Regulation Of Developmental Process DNA-binding Transcription Factor Binding Chromatin Binding RNA Polymerase II Transcription Regulator Complex Chromatin Organization Cellular Response To Stress Regulation Of Cell Population Proliferation RNA Polymerase II-specific DNA-binding Transcription Factor Binding	RNA Binding Nucleoplasm Nucleus Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Cytosol Cytoplasm MRNA Metabolic Process Macromolecule Metabolic Process MRNA Processing RNA Splicing RNA Processing Spliceosomal Complex RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Nucleic Acid Binding Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Protein Binding MRNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Protein-containing Complex Organization Catalytic Step 2 Spliceosome Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Nucleotide Binding ATP Binding Positive Regulation Of Macromolecule Biosynthetic Process Extracellular Exosome Protein-containing Complex Assembly Positive Regulation Of RNA Metabolic Process Ribonucleoprotein Complex Positive Regulation Of Biosynthetic Process Cadherin Binding Regulation Of DNA Metabolic Process Chromatin Binding Ficolin-1-rich Granule Lumen Nucleolus Regulation Of Gene Expression Cellular Component Assembly Proteasome Complex Nuclear Speck Negative Regulation Of Macromolecule Metabolic Process Cytoplasmic Stress Granule ATP Hydrolysis Activity Positive Regulation Of RNA Biosynthetic Process
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