CMYA5 and MYBPC2

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		CMYA5	MYBPC2
Description		cardiomyopathy associated 5	myosin binding protein C2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Sarcoplasmic Reticulum M Band Perinuclear Region Of Cytoplasm	Cytosol M Band Myosin Filament
	Molecular Function		Actin Binding Protein Binding Structural Constituent Of Muscle
	Biological Process		Cell Adhesion Sarcomere Organization
Pathways			Striated Muscle Contraction
Drugs
Diseases
GWAS		Bone mineral content ( 31790847) Hepatitis B surface antigen seroclearance in chronic hepatitis B infection ( 29975729) Obesity ( 23818313) Toenail selenium levels ( 25343990)	Primary biliary cholangitis ( 26394269)
Interacting Genes		10 interacting genes: CAPN3 CLIP4 DTNBP1 DYSF HSPB2 IL6ST MYBPC2 OPTN PKNOX1 SNAPIN	31 interacting genes: ACTN2 AMOT AOC3 CCT6A CMYA5 COL12A1 DST DYSF FLNB FLNC FSD2 GABARAP GAS7 HSPA1B ITGB5 MAD2L2 MSN MYBPC1 MYBPH MYH8 MYOM2 NF2 PCDH12 PDE4DIP RANBP2 SDCBP SGCG TRIM63 TRIP11 TTN TULP3
Entrez ID		202333	4606
HPRD ID		16728	01184
Ensembl ID		ENSG00000164309	ENSG00000086967
Uniprot IDs		Q8N3K9	A0A140VJQ0 Q14324
PDB IDs			2E7C 2EDK 2EDN
Enriched GO Terms of Interacting Partners?		Regulation Of Neurotransmitter Secretion Anterograde Synaptic Vesicle Transport BLOC-1 Complex Synaptic Vesicle Membrane Structural Constituent Of Muscle T-tubule Sarcomere Organization Vesicle Transport Along Microtubule Synaptic Vesicle Transport Anterograde Axonal Transport Melanosome Organization Pigment Granule Organization Regulation Of Synaptic Vesicle Exocytosis Calcium-dependent Self Proteolysis Monocyte Activation Involved In Immune Response Vesicle Cytoskeletal Trafficking Positive Regulation Of Late Endosome To Lysosome Transport Axon Cytoplasm Axonal Transport Ligase Regulator Activity Positive Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Actin Cytoskeleton Organization Response To Unfolded Protein Interleukin-27 Receptor Activity Leukemia Inhibitory Factor Receptor Activity Interleukin-6 Binding Interleukin-6 Receptor Activity Oncostatin-M Receptor Complex Cytoplasmic Vesicle Axo-dendritic Transport Organelle Transport Along Microtubule Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Organelle Organization Actin Filament-based Process Cytoskeleton Organization Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Oncostatin-M Receptor Activity Interleukin-6 Receptor Complex Ciliary Neurotrophic Factor Receptor Complex Establishment Of Vesicle Localization Actomyosin Structure Organization Sarcolemma Somatic Muscle Development Ciliary Neurotrophic Factor Receptor Activity Leukemia Inhibitory Factor Signaling Pathway Interleukin-11 Receptor Activity Oncostatin-M-mediated Signaling Pathway Interleukin-11 Binding Vesicle Localization Regulation Of Regulated Secretory Pathway	Actin Filament-based Process M Band Actin Cytoskeleton Organization Cytoskeleton Organization Sarcomere Organization Structural Constituent Of Muscle Actomyosin Structure Organization Myosin Filament Z Disc Cytoskeletal Protein Binding Organelle Organization Actin Binding Cytoskeleton Focal Adhesion Titin Binding Positive Regulation Of Organelle Organization Cytoplasm Positive Regulation Of Supramolecular Fiber Organization Cell Adhesion Positive Regulation Of Cytoskeleton Organization Actin Filament Binding Myofibril Positive Regulation Of Microtubule Nucleation Positive Regulation Of Early Endosome To Late Endosome Transport Actin Cytoskeleton Integrin Binding Positive Regulation Of Protein Localization To Early Endosome Regulation Of Organelle Organization Positive Regulation Of Protein Localization To Endosome Positive Regulation Of Cellular Component Biogenesis Muscle Filament Sliding Phosphatidylinositol-4,5-bisphosphate Binding Filopodium Pseudopodium Actin-myosin Filament Sliding Regulation Of Early Endosome To Late Endosome Transport Muscle Contraction Stress Fiber Regulation Of Microtubule Nucleation Regulation Of Supramolecular Fiber Organization Extracellular Exosome Calcium Ion Binding Positive Regulation Of Cellular Component Organization Plasma Membrane Enzyme Binding Muscle Cell Development Sarcolemma Muscle System Process Regulation Of Organelle Assembly Regulation Of Intracellular Transport
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?