LCE1D and RAD54L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LCE1D	RAD54L2
Description		late cornified envelope 1D	RAD54 like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Perinuclear Region Of Cytoplasm	Nucleus Nuclear Body
	Molecular Function	Protein Binding Identical Protein Binding	Nucleotide Binding DNA Binding Transcription Coregulator Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity ATP-dependent Chromatin Remodeler Activity
	Biological Process	Epidermis Development Keratinization Cognition Cellular Response To Calcium Ion	Chromatin Organization Chromatin Remodeling Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)	Estimated glomerular filtration rate ( 31152163)
Interacting Genes		69 interacting genes: ADAMTSL4 ALPP AMOT CATSPER1 CHIC2 CRCT1 CYP21A2 CYSRT1 FBLN1 GRN HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE4A LCE5A MACO1 MDFI MEOX2 NBPF19 NOTCH2NLA NTAQ1 NUFIP2 PCSK5 PIAS4 RAD54L2 RGS17 RGS20 RNF4 SCARF1 SMCP SPRY1 TGFB1 TRIM42 UBE2I	44 interacting genes: AR ATN1 ATXN1 ATXN1L BANP BHLHE40 CBX3 CRK FAM118B FXR2 HMG20A HNRNPCL1 HOMER1 IMPDH1 KIFC3 KRTAP6-3 LCE1D LCE1F NR3C1 NR5A1 NR5A2 PAICS PIAS1 POU1F1 PPARG PSMA3 RAD51 RBPMS RUNX1T1 RXRA SIAH1 SQSTM1 SUMO1 SUMO2 SUMO3 TAX1BP1 TFAP2D THAP1 TRAF2 TRAF4 UBE2I VCX ZBTB26 ZC2HC1A
Entrez ID		353134	23132
HPRD ID		13968	10018
Ensembl ID		ENSG00000172155	ENSG00000164080
Uniprot IDs		Q5T752	B3KV54 Q9Y4B4
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Epidermis Development Keratinization Hair Cycle Tissue Development Identical Protein Binding Protein Binding Negative Regulation Of Protein Localization To Chromatin	Identical Protein Binding Enzyme Binding PML Body Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Transcription Coregulator Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Receptor Activity Nucleus Postsynaptic Cytosol Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Nucleobase-containing Compound Biosynthetic Process Protein Sumoylation Nucleoplasm Negative Regulation Of Macromolecule Biosynthetic Process Transcription By RNA Polymerase II 'de Novo' XMP Biosynthetic Process Presynaptic Cytosol Ubiquitin Protein Ligase Binding Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Intracellular Receptor Signaling Pathway Signaling Adaptor Activity Hormone-mediated Signaling Pathway Chromatin Regulation Of Primary Metabolic Process Chromatin Binding GMP Biosynthetic Process IMP Dehydrogenase Activity DNA-binding Transcription Factor Activity Negative Regulation Of Metabolic Process Protein Tag Activity Purine Ribonucleoside Monophosphate Biosynthetic Process Zinc Ion Binding Regulation Of Gene Expression SUMO Transferase Activity Sequence-specific DNA Binding Double-stranded DNA Binding RNA Polymerase II Transcription Regulator Complex Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Metabolic Process
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