DPYSL2 and CRMP1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (in vivo)

		DPYSL2	CRMP1
Gene Name		dihydropyrimidinase-like 2	collapsin response mediator protein 1
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol Microtubule Membrane Dendrite Growth Cone Neuronal Cell Body Terminal Bouton Extracellular Vesicular Exosome	Cytoplasm Microtubule Organizing Center Spindle Cytosol Dendrite Neuronal Cell Body
	Molecular Function	Dihydropyrimidinase Activity Protein Binding Protein Kinase Binding	Protein Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides
	Biological Process	Response To Amphetamine Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Endocytosis Cytoskeleton Organization Signal Transduction Nervous System Development Axon Guidance Regulation Of Neuron Projection Development Positive Regulation Of Glutamate Secretion Spinal Cord Development Olfactory Bulb Development Response To Cocaine Response To Drug Synaptic Vesicle Transport	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Nervous System Development Axon Guidance
Pathways		Axon guidance Semaphorin interactions L1CAM interactions CRMPs in Sema3A signaling Recycling pathway of L1	Axon guidance Semaphorin interactions CRMPs in Sema3A signaling
Drugs
Diseases
GWAS			Blood trace element (Zn levels) ( 23720494)
Protein-Protein Interactions		14 interactors: AP2A1 CRMP1 DISC1 DPYSL3 DPYSL4 DPYSL5 GORASP2 GSK3B LEF1 NUMB PLD2 ROCK1 TNIK TUBB	78 interactors: AGR2 ALDH2 AMFR ANXA7 AP3M1 ARL15 AXIN1 BID BTBD2 CACNA1A CCDC106 CCL18 CCT7 CDK5RAP2 CDK5RAP3 DDX18 DNAJB11 DPYSL2 DPYSL3 DUSP4 EEF1D EIF2S2 EPN1 EXOSC8 FAS FTH1 FUBP1 FXR1 GNE GOLGA2 HDHD2 HGS HMGB1 HNRNPH1 HNRNPH3 HNRNPUL1 HSPE1 HTT IL33 KLHL20 LRRC1 LSM2 MAPK8IP2 MCM3AP MOB4 MRPS12 NAT9 NDUFV2 NVL PAFAH1B3 PFN1 PLA2G2A PMF1 PPP1R8 PSMD11 RGL2 RGS2 ROCK1 RPA2 RPS6KA5 RTN4 SAT1 SEPHS1 SERPINB9 SNRPG SPRY2 SRC TFG TK1 TRIP13 TSC22D1 UBE2A UBE2B VCP VIM YAE1D1 ZAK ZNF24
Entrez ID		1808	1400
HPRD ID		03914	03913
Ensembl ID		ENSG00000092964	ENSG00000072832
Uniprot IDs		Q16555 Q59GB4	B3KT07 E9PD68 Q14194 Q96I11
PDB IDs		2GSE 2VM8	4B3Z
Enriched GO Terms of Interacting Partners?		Pyrimidine Nucleobase Catabolic Process Chemotaxis Axon Guidance Movement Of Cell Or Subcellular Component Generation Of Neurons Cell Morphogenesis Involved In Differentiation Neurogenesis Locomotion Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Morphogenesis Cell Morphogenesis Neuron Differentiation Nervous System Development Cell Projection Organization Neuron Projection Development Pyrimidine Nucleobase Metabolic Process Cell Projection Morphogenesis Cell Part Morphogenesis Neuron Development Cell Development Response To External Stimulus Cell Differentiation System Development Anatomical Structure Morphogenesis Multicellular Organismal Development Regulation Of Cell Development Anatomical Structure Development Positive Regulation Of Cell Development Response To Stimulus Regulation Of Cell Differentiation Wnt Signaling Pathway Developmental Process Telencephalon Development Canonical Wnt Signaling Pathway Cytoskeleton Organization Forebrain Neuroblast Division Neural Precursor Cell Proliferation Regulation Of Neurogenesis Regulation Of Cellular Component Organization Regulation Of Neuron Projection Development Regulation Of Epithelial Cell Differentiation Positive Regulation Of Neurogenesis Positive Regulation Of Cell Differentiation Forebrain Development Somatic Stem Cell Division Cell Surface Receptor Signaling Pathway Organelle Organization Regulation Of Cell Projection Organization	Cell Death Death Developmental Process Apoptotic Process Programmed Cell Death Anatomical Structure Development Regulation Of Cellular Protein Metabolic Process Cell Differentiation Catabolic Process Regulation Of Apoptotic Process Regulation Of Protein Metabolic Process Cellular Response To Stress Regulation Of Cell Death Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Proteolysis Regulation Of Cysteine-type Endopeptidase Activity Response To Stimulus Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Cellular Protein Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Organic Substance Protein Homooligomerization Response To Stress Protein Polyubiquitination Positive Regulation Of Protein Complex Assembly Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Nitrogen Compound Metabolic Process Cellular Response To Stimulus Multicellular Organismal Development Cytoskeleton Organization Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Proteolysis Cellular Process Stress-activated MAPK Cascade Nervous System Development Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Metabolic Process Cellular Component Assembly Positive Regulation Of Cysteine-type Endopeptidase Activity System Development Positive Regulation Of Catalytic Activity Postreplication Repair Regulation Of Cellular Component Organization Protein Oligomerization Cellular Macromolecule Catabolic Process Positive Regulation Of Endopeptidase Activity Regulation Of Protein Complex Assembly Heterocycle Metabolic Process
Tagcloud ?		24months 2de 8months astrocytic avenues coactosin creatine diamond dihydropyrimidinase dynamin e693delta glutamic glyoxalase illuminate isocitrate littermates oligomers pea phosphoprotein phosphoproteins possessed presumed profilin ruby sh3 sypro transgenic triphosphatase vacuolar	aldh1a1 anxa1 bcar1 cldn1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Difference) ?		24months 2de 8months astrocytic avenues coactosin creatine diamond dihydropyrimidinase dynamin e693delta glutamic glyoxalase illuminate isocitrate littermates oligomers pea phosphoprotein phosphoproteins possessed presumed profilin ruby sh3 sypro transgenic triphosphatase vacuolar	aldh1a1 anxa1 bcar1 cldn1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Intersection) ?