MYC and BCL2

  • Number of citations of the paper that reports this interaction (PMID 15210690)
  • 27
  • Data Source:
  • BioGRID (affinity chromatography technology, imaging technique)
  • HPRD (in vitro)

MYC

BCL2

Gene Name v-myc avian myelocytomatosis viral oncogene homolog B-cell CLL/lymphoma 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 126 interactors: ACTL6A ATAD2 AXIN1 BCL2 BIN1 BRCA1 BRD3 BTRC CCNH CCNT1 CDC6 CDCA7L CDK1 CDK4 CDK6 CDK8 CDKN2A CEBPA CEBPB CEP57 CREB1 CREBBP CSNK2A1 CSNK2A2 DNMT3A EFNB1 ELF3 EP300 EP400 FBXO8 FBXW7 FBXW8 GCN1L1 GPX2 GSK3A GSK3B GTF2B GTF2F1 GTF2I HNRNPD HSP90AA1 HUWE1 ING4 KAT2A KAT2B KAT5 KDM1A KIAA1524 KIDINS220 KPNA2 LDOC1 MAP2K1 MAPK1 MAPK3 MAPK7 MAPK8 MAX MED1 MED12 MED14 MED16 MEN1 MINA MLH1 MOK MXD1 MXI1 MYCBP MYCBP2 NEK11 NFYB NFYC NMI NOTCH3 NUCB1 PAK2 PARP10 PFDN5 PLAU PML POLR2A PRDX1 PSMC3 RAF1 RB1 RBL1 RELA RUVBL1 SAP130 SF3B1 SKP1 SKP2 SMAD2 SMAD3 SMARCA2 SMARCA4 SMARCB1 SMARCC1 SNIP1 SNRNP70 SP1 SPAG9 SUPT3H TADA2A TAF1B TAF5 TAF9 TBP TFAP2A TFAP2B TIAM1 TONSL TP73 TRIM6 TRRAP TUBA1A TUBA1B TUBA3C TUBA4A TUBA8 UBB USP37 YEATS4 YY1 ZBTB17 ZNF281 83 interactors: ATP2A2 BAD BAG1 BAG3 BAG4 BAK1 BAX BBC3 BCAP31 BCL2L1 BCL2L10 BCL2L11 BCL2L14 BCLAF1 BECN1 BFAR BID BIK BLK BMF BNIP1 BNIP2 BNIP3 BNIP3L BNIPL CAPN2 CASP3 CASP8 CDK1 CDK2 CPT1A CYCS EPHB2 FKBP8 HNRNPD HRAS HRK HSPA1A ITM2B ITPR1 KRAS MAPK1 MAPK11 MAPK14 MAPK3 MAPK8 MEX3D MOAP1 MYC NLRP1 NMT2 NR4A1 NRAS PARP1 PIN1 PKMYT1 PMAIP1 PML PPID PPP1CA PPP2CA PPP2R4 PPP2R5A PPP3CA PPP3CC PRKACA PRKCA PSEN1 PXN RAD9A RAF1 RRAS RTN4 SF1 SMN1 SOD1 SPNS1 SQSTM1 TMBIM6 TOMM20 TP53 TP53AIP1 TP53BP2
Entrez ID 4609 596
HPRD ID 01818 01045
Ensembl ID ENSG00000136997 ENSG00000171791
Uniprot IDs P01106 C9JHD5 P10415
PDB IDs 1A93 1EE4 1MV0 1NKP 2A93 2OR9 1G5M 1GJH 1YSW 2O21 2O22 2O2F 2W3L 2XA0 4AQ3 4IEH 4LVT 4LXD 4LXE
Enriched GO Terms of Interacting Partners?
Tagcloud ?
augment  augments  bait  cbp  coactivator  coil  coiled  enhances  except  hybrid  ifngamma  instead  interactor  interacts  interestingly  intrinsic  lacks  nmi  potentiate  recruitment  reveal  screen  stat  stat1  stat2  stat5  stat5b  stats  yeast 
adenocarcinomas  anthracene  carcinogenic  chorionic  dawley  dimethylbenz  dmba  elevation  exists  glands  gonadotropin  hcg  ice  iu  makes  mammary  modulated  myc  ovaries  phenomenon  probed  programmed  rnas  sprague  trpm2  virgin  xl  xs 
Tagcloud (Difference) ?
augment  augments  bait  cbp  coactivator  coil  coiled  enhances  except  hybrid  ifngamma  instead  interactor  interacts  interestingly  intrinsic  lacks  nmi  potentiate  recruitment  reveal  screen  stat  stat1  stat2  stat5  stat5b  stats  yeast 
adenocarcinomas  anthracene  carcinogenic  chorionic  dawley  dimethylbenz  dmba  elevation  exists  glands  gonadotropin  hcg  ice  iu  makes  mammary  modulated  ovaries  phenomenon  probed  programmed  rnas  sprague  trpm2  virgin  xl  xs 
Tagcloud (Intersection) ?
myc