GRID1 and LILRB3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GRID1	LILRB3
Description		glutamate ionotropic receptor delta type subunit 1	leukocyte immunoglobulin like receptor B3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane AMPA Glutamate Receptor Complex Dendritic Spine Synapse Postsynaptic Membrane Extracellular Exosome Trans-synaptic Protein Complex Postsynaptic Density Membrane Glutamatergic Synapse GABA-ergic Synapse	Plasma Membrane Membrane Secretory Granule Membrane
	Molecular Function	AMPA Glutamate Receptor Activity Monoatomic Ion Channel Activity Protein Binding Ligand-gated Monoatomic Ion Channel Activity GABA Receptor Activity Signaling Receptor Activity Identical Protein Binding G Protein-coupled Receptor Activity Involved In Regulation Of Postsynaptic Membrane Potential Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	Amyloid-beta Binding Transmembrane Signaling Receptor Activity Protein Binding Inhibitory MHC Class I Receptor Activity Signaling Receptor Activity
	Biological Process	Monoatomic Ion Transport Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Synaptic Plasticity Monoatomic Ion Transmembrane Transport Social Behavior Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Synaptic Plasticity Modulation Of Chemical Synaptic Transmission Regulation Of Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Regulation Of Postsynapse Organization Synaptic Signaling Via Neuropeptide	Adaptive Immune Response Immune System Process Immune Response-regulating Signaling Pathway Defense Response Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Negative Regulation Of Osteoclast Differentiation
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Anorexia nervosa ( 23568457) Asthma ( 27611488) Asthma (childhood onset) ( 27611488) Balding ( 26926045) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body size at age 10 ( 32376654) Cardiac structure and function ( 19584346) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) Femur bone mineral density x serum urate levels interaction ( 34046847) HDL cholesterol levels ( 32109663) Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334) Non-del(5q) myelodysplastic syndromes ( 31738830) Pancreatic cancer ( 23180869) Periodontal microbiota ( 22699663) Post-traumatic stress disorder symptoms in trauma-exposed soldiers ( 30999091) Renal overload gout ( 32238385) Smoking status (ever vs never smokers) ( 30643258) Spontaneous preterm birth without premature rupture of membranes ( 31194736) Stearic acid (18:0) levels ( 23362303) Superior temporal sulcus banks volume ( 31530798)	Birth weight ( 31043758) Monocyte count ( 32888494) Takayasu arteritis ( 25604533)
Interacting Genes		5 interacting genes: DLG2 EML1 GOPC LILRB3 MTDH	3 interacting genes: CHRNA1 GRID1 RPL38
Entrez ID		2894	11025
HPRD ID		17078	11995
Ensembl ID		ENSG00000182771	ENSG00000204577
Uniprot IDs		A8KAN9 Q9ULK0	C9JWL8
PDB IDs		8BLJ 8BN2 8BN5
Enriched GO Terms of Interacting Partners?		Retrograde Axonal Protein Transport Negative Regulation Of Anion Channel Activity	Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential Synapse Regulation Of Postsynaptic Membrane Potential 90S Preribosome Assembly Eukaryotic 80S Initiation Complex Monoatomic Ion Channel Activity Postsynaptic Membrane G Protein-coupled Receptor Activity Involved In Regulation Of Postsynaptic Membrane Potential Negative Regulation Of Synaptic Plasticity Skeletal Muscle Tissue Growth Chemical Synaptic Transmission GABA Receptor Activity Trans-synaptic Protein Complex AMPA Glutamate Receptor Activity Axial Mesoderm Development Trans-synaptic Signaling Synaptic Signaling Acetylcholine Binding Synaptic Signaling Via Neuropeptide Regulation Of Membrane Potential Acetylcholine Receptor Activity Musculoskeletal Movement Acetylcholine-gated Monoatomic Cation-selective Channel Activity Modulation Of Chemical Synaptic Transmission Acetylcholine-gated Channel Complex Cell-cell Signaling Middle Ear Morphogenesis Synaptic Transmission, Cholinergic Signaling Muscle Cell Cellular Homeostasis Cell Communication AMPA Glutamate Receptor Complex Neuronal Action Potential Monoatomic Ion Transmembrane Transport Neuromuscular Synaptic Transmission Postsynaptic Specialization Membrane Ionotropic Glutamate Receptor Signaling Pathway Ligand-gated Monoatomic Ion Channel Activity Skeletal Muscle Contraction Extracellular Ligand-gated Monoatomic Ion Channel Activity Neuromuscular Junction Development Presynaptic Modulation Of Chemical Synaptic Transmission Response To Nicotine Acetylcholine Receptor Signaling Pathway Nervous System Process Synaptic Transmission, Glutamatergic Ligand-gated Ion Channel Signaling Pathway Monoatomic Ion Transport Postsynaptic Signal Transduction Glutamate Receptor Signaling Pathway
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