GRID1

Description		glutamate ionotropic receptor delta type subunit 1
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GO Annotations	Cellular Component	Plasma Membrane Membrane AMPA Glutamate Receptor Complex Dendritic Spine Synapse Postsynaptic Membrane Extracellular Exosome Trans-synaptic Protein Complex Postsynaptic Density Membrane Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	AMPA Glutamate Receptor Activity Monoatomic Ion Channel Activity Protein Binding Ligand-gated Monoatomic Ion Channel Activity GABA Receptor Activity Signaling Receptor Activity Identical Protein Binding G Protein-coupled Receptor Activity Involved In Regulation Of Postsynaptic Membrane Potential Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Monoatomic Ion Transport Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Synaptic Plasticity Monoatomic Ion Transmembrane Transport Social Behavior Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Synaptic Plasticity Modulation Of Chemical Synaptic Transmission Regulation Of Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Regulation Of Postsynapse Organization Synaptic Signaling Via Neuropeptide
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Anorexia nervosa ( 23568457) Asthma ( 27611488) Asthma (childhood onset) ( 27611488) Balding ( 26926045) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body size at age 10 ( 32376654) Cardiac structure and function ( 19584346) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) Femur bone mineral density x serum urate levels interaction ( 34046847) HDL cholesterol levels ( 32109663) Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334) Non-del(5q) myelodysplastic syndromes ( 31738830) Pancreatic cancer ( 23180869) Periodontal microbiota ( 22699663) Post-traumatic stress disorder symptoms in trauma-exposed soldiers ( 30999091) Renal overload gout ( 32238385) Smoking status (ever vs never smokers) ( 30643258) Spontaneous preterm birth without premature rupture of membranes ( 31194736) Stearic acid (18:0) levels ( 23362303) Superior temporal sulcus banks volume ( 31530798)
Interacting Genes		5 interacting genes: DLG2 EML1 GOPC LILRB3 MTDH
Entrez ID		2894
HPRD ID		17078
Ensembl ID		ENSG00000182771
Uniprot IDs		A8KAN9 Q9ULK0
PDB IDs		8BLJ 8BN2 8BN5
Enriched GO Terms of Interacting Partners?		Retrograde Axonal Protein Transport Negative Regulation Of Anion Channel Activity
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