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DIO2 and UBE2G1
Number of citations of the paper that reports this interaction (PMID
17452445
)
22
Data Source:
BioGRID
(fluorescent resonance energy transfer, pull down)
DIO2
UBE2G1
Gene Name
deiodinase, iodothyronine, type II
ubiquitin-conjugating enzyme E2G 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Membrane
Integral Component Of Membrane
Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
Thyroxine 5'-deiodinase Activity
Selenium Binding
Ubiquitin Protein Ligase Binding
Ubiquitin-protein Transferase Activity
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Biological Process
Selenocysteine Incorporation
Thyroid Hormone Generation
Cellular Nitrogen Compound Metabolic Process
Thyroid Hormone Metabolic Process
Hormone Biosynthetic Process
Small Molecule Metabolic Process
Oxidation-reduction Process
Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Catabolic Process
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Pathways
Amine-derived hormones
Regulation of thyroid hormone activity
Thyroxine biosynthesis
Metabolism of amino acids and derivatives
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
6 interactors:
MARCH6
UBE2G1
UBE2J1
USP20
USP33
WSB1
13 interactors:
AMFR
APP
CBL
DIO2
HUWE1
ITCH
MARCH6
PARK2
RBCK1
RBX1
UBA1
UBE2E1
UBE3A
Entrez ID
1734
7326
HPRD ID
09027
03340
Ensembl ID
ENSG00000211448
ENSG00000132388
Uniprot IDs
A8K845
Q92813
Q9HCP7
P62253
PDB IDs
2AWF
Enriched GO Terms of Interacting Partners
?
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Catabolic Process
Protein K48-linked Deubiquitination
Cellular Protein Modification Process
Protein K63-linked Deubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Proteasomal Protein Catabolic Process
Protein K48-linked Ubiquitination
Cellular Protein Metabolic Process
Protein Metabolic Process
Proteolysis
Protein Deubiquitination
Protein Modification By Small Protein Removal
Catabolic Process
Protein Polyubiquitination
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Protein Catabolic Process
Cellular Metabolic Process
Protein K63-linked Ubiquitination
Centrosome Duplication
ER-associated Ubiquitin-dependent Protein Catabolic Process
Endocytosis
Regulation Of Proteolysis
Negative Regulation Of Protein Binding
Centrosome Cycle
Positive Regulation Of Protein Binding
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Polyubiquitination
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Protein K48-linked Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Cellular Protein Metabolic Process
Cellular Protein Modification Process
Catabolic Process
Protein Monoubiquitination
Protein Metabolic Process
Proteolysis
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Protein K29-linked Ubiquitination
Cellular Metabolic Process
Cellular Response To Stimulus
Regulation Of Protein Catabolic Process
Notch Signaling Pathway
Negative Regulation Of JNK Cascade
Protein K63-linked Ubiquitination
Intracellular Receptor Signaling Pathway
Viral Process
Regulation Of Protein Ubiquitination
Negative Regulation Of Stress-activated MAPK Cascade
Histone Ubiquitination
Positive Regulation Of Protein Catabolic Process
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Protein Autoubiquitination
Regulation Of Signal Transduction
Response To Stimulus
Regulation Of Cellular Protein Metabolic Process
Regulation Of Proteolysis
Learning Or Memory
Cognition
Positive Regulation Of Proteolysis
Regulation Of Signaling
Negative Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Protein Metabolic Process
Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Sperm Entry
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Mitochondrial Fusion
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Signaling
Tagcloud
?
cga
deiodinase
hypothalamic
hypothalamus
intra
intraperitoneal
ko
littermates
mct
mct8
nbr
neuromedin
paracrine
pituitary
releasing
slc16a2
slight
t3
t4
thrb
thyroid
thyroidal
thyrotropin
thyroxine
trh
trhr
triiodothyronine
tsh
tshb
Tagcloud (Difference)
?
cga
deiodinase
hypothalamic
hypothalamus
intra
intraperitoneal
ko
littermates
mct
mct8
nbr
neuromedin
paracrine
pituitary
releasing
slc16a2
slight
t3
t4
thrb
thyroid
thyroidal
thyrotropin
thyroxine
trh
trhr
triiodothyronine
tsh
tshb
Tagcloud (Intersection)
?