DIAPH2 and NCKIPSD

Number of citations of the paper that reports this interaction (PMID 11509578)
22

Data Source:
HPRD (in vitro, in vivo)

		DIAPH2	NCKIPSD
Gene Name		diaphanous-related formin 2	NCK interacting protein with SH3 domain
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Mitochondrion Early Endosome Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle	Cytosol Intermediate Filament COP9 Signalosome
	Molecular Function	Actin Binding Receptor Binding Rho GTPase Binding	Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding
	Biological Process	Cytokinesis Multicellular Organismal Development Female Gamete Generation Actin Filament Polymerization Oogenesis	NLS-bearing Protein Import Into Nucleus Cytoskeleton Organization Signal Transduction Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response
Pathways			Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: APBB1 CDC42 CENPA NCKIPSD RHOD TCERG1	19 interactors: ARHGEF7 BAIAP2 DIAPH2 DIAPH3 DLG4 DMRTB1 FASLG GRB2 ITGB1 KHDRBS1 MAPK3 NCK1 NCK2 PSMD9 SORBS3 STAC WAS WASL YWHAG
Entrez ID		1730	51517
HPRD ID		02117	09450
Ensembl ID		ENSG00000147202	ENSG00000213672
Uniprot IDs		O60879 Q17R91	Q9NZQ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Actin Filament Bundle Assembly Cellular Protein Localization Adherens Junction Organization Organelle Organization Negative Regulation Of Thymidylate Synthase Biosynthetic Process Positive Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of DNA Metabolic Process Protein Localization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Establishment Of Localization In Cell Actin Filament Branching Submandibular Salivary Gland Formation Establishment Or Maintenance Of Cell Polarity Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Regulation Of Cell-substrate Adhesion Cell-cell Junction Organization Cellular Localization Establishment Of Golgi Localization Positive Regulation Of Metalloenzyme Activity Phagocytosis Fc Receptor Signaling Pathway Cell Projection Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Neuron Fate Determination Epithelial-mesenchymal Cell Signaling Cell Projection Assembly Regulation Of Protein Heterodimerization Activity Actin Filament Organization Keratinocyte Development Regulation Of Synapse Structural Plasticity Establishment Of Organelle Localization Protein Localization To Chromosome, Centromeric Region Positive Regulation Of Pseudopodium Assembly Nuclear Migration Cardiac Conduction System Development Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Golgi Localization Axon Guidance Filopodium Assembly Organelle Localization Protein Targeting Intracellular Transport Hair Follicle Placode Formation Macrophage Differentiation NLS-bearing Protein Import Into Nucleus	Actin Cytoskeleton Organization Actin Filament-based Process Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Axon Guidance Positive Regulation Of Organelle Organization Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Actin Filament Organization Regulation Of Cytoskeleton Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Cellular Component Organization Cytoskeleton Organization Neuron Projection Development Cell Projection Morphogenesis Regulation Of Actin Cytoskeleton Organization Cell Part Morphogenesis Positive Regulation Of Cytoskeleton Organization Chemotaxis Positive Regulation Of Signal Transduction Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Neuron Development Cell Development Cellular Component Assembly Regulation Of Signaling Cell Morphogenesis Phagocytosis Fc Receptor Signaling Pathway Neuron Differentiation Immune Response-activating Cell Surface Receptor Signaling Pathway Generation Of Neurons Cell Projection Organization Neurogenesis Immune System Process Regulation Of Signal Transduction Signal Transduction Response To External Stimulus Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Endocytosis Regulation Of ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Organelle Organization Protein Complex Assembly Signaling Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation
Tagcloud ?			2d 3d 4ebp1 adenocarcinomas atr atrip clearer concordant discordant egr emphasized gliomas growths gsk3alphabeta hypoxia look mek1 monolayer nfkappabetap65 normoxia phosphoprotein reflective s6 ser235 ser240 ser423 ser65 smad3 vegfr2
Tagcloud (Difference) ?			2d 3d 4ebp1 adenocarcinomas atr atrip clearer concordant discordant egr emphasized gliomas growths gsk3alphabeta hypoxia look mek1 monolayer nfkappabetap65 normoxia phosphoprotein reflective s6 ser235 ser240 ser423 ser65 smad3 vegfr2
Tagcloud (Intersection) ?