RBP1 and MED26

Number of citations of the paper that reports this interaction (PubMedID 15175163)
0

Data Source:
HPRD (in vitro)

		RBP1	MED26
Description		retinol binding protein 1	mediator complex subunit 26
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Lipid Droplet Cytosol	Nucleus Nucleoplasm Mediator Complex Core Mediator Complex
	Molecular Function	Retinoid Binding Fatty Acid Binding Protein Binding Lipid Binding Retinal Binding Retinol Binding All-trans-retinol Binding	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding
	Biological Process	Retinoic Acid Biosynthetic Process Vitamin A Metabolic Process Fatty Acid Transport Lipid Homeostasis	Regulation Of Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription Elongation By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways		The canonical retinoid cycle in rods (twilight vision) Retinoid metabolism and transport Defective visual phototransduction due to LRAT loss of function	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions
Drugs		Acitretin
Diseases
GWAS			Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
Interacting Genes		18 interacting genes: BRMS1 BRMS1L CYTOR DHPS HDAC1 HDAC2 IKBKG ING1 LRAT LRP2 MED26 RBBP4 RBBP7 SAP30 SIN3A TNFRSF10D TTC19 UBE2J2	8 interacting genes: AURKA CDK8 CTDP1 MED12 MED8 MED9 RBP1 SREBF1
Entrez ID		5947	9441
HPRD ID		07036	05437
Ensembl ID		ENSG00000114115	ENSG00000105085
Uniprot IDs		A0A0A0MQT0 P09455	O95402
PDB IDs		5H8T 5H9A 5HA1 5HBS 5LJB 5LJC 5LJD 5LJE 5LJG 5LJH 5LJK 6E5L 6E5T 6E6M 8GD2 8GDM 8GEM 8GEU 8GEV 8GEY	5ODD 6ZV3 7EMF 7ENA 7ENC 7ENJ 8GXQ 8GXS
Enriched GO Terms of Interacting Partners?		Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Histone Deacetylase Complex Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Locomotion NuRD Complex Regulation Of Cell Fate Specification Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Positive Regulation Of Multicellular Organismal Process Negative Regulation Of Developmental Process Regulation Of Cell Fate Commitment Regulation Of Cell Migration Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Developmental Process Histone Deacetylase Binding Regulation Of Cell Motility Regulation Of Locomotion ESC/E(Z) Complex Negative Regulation Of Multicellular Organismal Process Regulation Of Stem Cell Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Lysine Delactylase Activity Fungiform Papilla Formation Negative Regulation Of RNA Metabolic Process NF-kappaB Binding Protein Decrotonylase Activity Histone Decrotonylase Activity Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleosomal DNA Binding Hair Follicle Placode Formation Cellular Response To Dopamine NURF Complex Response To Dopamine Regulation Of Multicellular Organismal Process Positive Regulation Of Gliogenesis Regulation Of Developmental Process Histone Deacetylase Activity, Hydrolytic Mechanism Regulation Of Signal Transduction	Mediator Complex CKM Complex Positive Regulation Of DNA-templated Transcription Initiation Positive Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Transcription Coregulator Activity Spindle Midzone Core Mediator Complex Nucleoplasm Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Elongation By RNA Polymerase II Response To Metformin Positive Regulation Of DNA-templated Transcription, Elongation Transcription Preinitiation Complex Assembly Positive Regulation Of Metabolic Process Nucleus Positive Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Positive Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Fatty Acid Metabolic Process Protein Modification Process TFIIF-class Transcription Factor Complex Binding Negative Regulation Of Developmental Growth Axis Elongation Involved In Somitogenesis Regulation Of Transcription Elongation By RNA Polymerase II All-trans-retinol Binding Sterol Response Element Binding Positive Regulation Of Oocyte Maturation Ubiquitin Ligase Complex Regulation Of DNA-templated Transcription Elongation Positive Regulation Of RNA Metabolic Process Spindle Assembly Involved In Female Meiosis I Germinal Vesicle Histone H3S10 Kinase Activity Regulation Of Ketone Metabolic Process Regulation Of Heart Rate By Chemical Signal Positive Regulation Of Lipid Metabolic Process Developmental Growth Involved In Morphogenesis GDF15-GFRAL Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Vitamin A Metabolic Process Retinoic Acid Biosynthetic Process Positive Regulation Of Small Molecule Metabolic Process Mitotic Cell Cycle Phase Transition
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